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    Ccdc33 coiled-coil domain containing 33 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315712, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc33provided by RGD
    Official Full Name
    coiled-coil domain containing 33provided by RGD
    Primary source
    RGD:1561126
    See related
    EnsemblRapid:ENSRNOG00000008219 AllianceGenome:RGD:1561126
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in peroxisome. Orthologous to human CCDC33 (coiled-coil domain containing 33). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 16.4), Spleen (RPKM 7.7) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc33 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (67331519..67430194, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (58434798..58534338, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (62809768..62910520, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480058 Neighboring gene uncharacterized LOC103693105 Neighboring gene cytochrome P450, family 11, subfamily a, polypeptide 1 Neighboring gene uncharacterized LOC120094173 Neighboring gene signaling receptor and transporter of retinol STRA6 Neighboring gene immunoglobulin superfamily containing leucine-rich repeat

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Ccdc33, a predominantly testis-expressed gene, encodes a putative peroxisomal protein. Kaczmarek K, et al. Cytogenet Genome Res, 2009. PMID 20068295
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 33

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014091.2 → NP_001014113.1  coiled-coil domain-containing protein 33 isoform 1

      See identical proteins and their annotated locations for NP_001014113.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q5XIR4
      UniProtKB/TrEMBL
      A0A8I5ZL14
      Related
      ENSRNOP00000055287.2, ENSRNOT00000058490.4
      Conserved Domains (1) summary
      cd00030
      Location:37 → 132
      C2; C2 domain

    2. NM_001413792.1 → NP_001400721.1  coiled-coil domain-containing protein 33 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A8I5ZL14

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      67331519..67430194 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265488.1 → XP_063121558.1  coiled-coil domain-containing protein 33 isoform X14

      UniProtKB/TrEMBL
      A0A8I6GE34

    2. XM_063265482.1 → XP_063121552.1  coiled-coil domain-containing protein 33 isoform X8

      UniProtKB/TrEMBL
      A0A8I5ZL14

    3. XM_017595656.3 → XP_017451145.1  coiled-coil domain-containing protein 33 isoform X6

      UniProtKB/TrEMBL
      A0A8I5ZL14

    4. XM_039081473.2 → XP_038937401.1  coiled-coil domain-containing protein 33 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZL14
      Conserved Domains (2) summary
      cd00030
      Location:37 → 132
      C2; C2 domain
      TIGR02168
      Location:384 → 713
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. XM_063265484.1 → XP_063121554.1  coiled-coil domain-containing protein 33 isoform X9

      UniProtKB/TrEMBL
      A0A8I5ZL14

    6. XM_039081476.2 → XP_038937404.1  coiled-coil domain-containing protein 33 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZL14
      Conserved Domains (2) summary
      cd00030
      Location:37 → 132
      C2; C2 domain
      TIGR02168
      Location:384 → 701
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    7. XM_063265481.1 → XP_063121551.1  coiled-coil domain-containing protein 33 isoform X7

      UniProtKB/TrEMBL
      A0A8I5ZL14

    8. XM_039081477.2 → XP_038937405.1  coiled-coil domain-containing protein 33 isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZL14
      Conserved Domains (2) summary
      cd00030
      Location:37 → 132
      C2; C2 domain
      TIGR02168
      Location:384 → 662
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    9. XM_039081474.2 → XP_038937402.1  coiled-coil domain-containing protein 33 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZL14
      Conserved Domains (2) summary
      cd00030
      Location:37 → 132
      C2; C2 domain
      TIGR02168
      Location:384 → 714
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    10. XM_039081478.2 → XP_038937406.1  coiled-coil domain-containing protein 33 isoform X10

      UniProtKB/TrEMBL
      A0A8I5ZL14
      Conserved Domains (1) summary
      TIGR02168
      Location:326 → 656
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    11. XM_063265485.1 → XP_063121555.1  coiled-coil domain-containing protein 33 isoform X11

    12. XM_063265486.1 → XP_063121556.1  coiled-coil domain-containing protein 33 isoform X12

    13. XM_063265487.1 → XP_063121557.1  coiled-coil domain-containing protein 33 isoform X13

    14. XM_039081475.2 → XP_038937403.1  coiled-coil domain-containing protein 33 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZL14
      Conserved Domains (2) summary
      cd00030
      Location:37 → 132
      C2; C2 domain
      TIGR02168
      Location:384 → 705
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_005487820.2 RNA Sequence

    2. XR_005487821.2 RNA Sequence

    3. XR_005487819.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XIR4.1 GenPept UniProtKB/Swiss-Prot:Q5XIR4

    Gene LinkOut

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