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    Tgap1l6 GTPase activating protein testicular GAP1 like 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499607, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tgap1l6provided by RGD
    Official Full Name
    GTPase activating protein testicular GAP1 like 6provided by RGD
    Primary source
    RGD:1564926
    See related
    AllianceGenome:RGD:1564926
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    AABR07010907.1
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in regulation of Rho protein signal transduction and signal transduction. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 67.0) See more
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    Genomic context

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    See Tgap1l6 in Genome Data Viewer
    Location:
    2q26
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (133748985..133798563)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (131750076..131797706)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (133075993..133123187)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC134478921 Neighboring gene uncharacterized LOC134485905 Neighboring gene prohibitin 1, pseudogene 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel testicular RhoGAP-domain protein induces apoptosis. Modarressi MH, et al. Biol Reprod, 2004 Dec. PMID 15306557, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein Tgap1l6
    Names
    rho GTPase-activating protein 20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      133748985..133798563
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282877.1 → XP_063138947.1  uncharacterized protein Tgap1l6 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZY49

    2. XM_063282878.1 → XP_063138948.1  uncharacterized protein Tgap1l6 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZY49
    Nucleotide Protein Strain
    Heading Accession and Version

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