PRNP prion protein (Kanno blood group) [Ochotona princeps (American pika)] - Gene

Summary

Gene symbol: PRNP
Gene description: prion protein (Kanno blood group)
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Ochotona princeps
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_07	current	mOchPri1.hap1 (GCF_030435755.1)	22	NC_080853.1 (35583806..35598612, complement)
102	previous assembly	OchPri4.0 (GCF_014633375.1)	4A	NC_050562.1 (1397568..1398326)

Chromosome 22 - NC_080853.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in protein homooligomerization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prion protein (Kanno blood group); prion protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001279818.1 → NP_001266747.1 prion protein (Kanno blood group) precursor

See identical proteins and their annotated locations for NP_001266747.1

Status: PROVISIONAL

Source sequence(s)

EU555402

UniProtKB/TrEMBL

B2CYC1, Q866W7

Conserved Domains (3) summary

smart00157
Location:23 → 239

PRP; Major prion protein

pfam00377
Location:133 → 250

Prion; Prion/Doppel alpha-helical domain

pfam11587
Location:4 → 28

Prion_bPrPp; Major prion protein bPrPp - N terminal