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    Disp2 dispatched RND transporter family member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311324, updated on 9-Dec-2024

    Summary

    Official Symbol
    Disp2provided by RGD
    Official Full Name
    dispatched RND transporter family member 2provided by RGD
    Primary source
    RGD:1309569
    See related
    EnsemblRapid:ENSRNOG00000026787 AllianceGenome:RGD:1309569
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in smoothened signaling pathway. Predicted to be active in membrane. Orthologous to human DISP2 (dispatched RND transporter family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 208.8) and Adrenal (RPKM 50.5) See more
    Orthologs
    NEW
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    Genomic context

    See Disp2 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (126216194..126231724)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (105762303..105777826)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (110574383..110589909)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 9B Neighboring gene proline, histidine and glycine rich 1 Neighboring gene kinetochore-localized astrin/SPAG5 binding protein Neighboring gene isovaleryl-CoA dehydrogenase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in smoothened signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein dispatched homolog 2
    Names
    dispatched homolog 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107759.2NP_001101229.2  protein dispatched homolog 2

      See identical proteins and their annotated locations for NP_001101229.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I6G3K8, A6HPC5, A6HPC6, D3ZBZ6
      Related
      ENSRNOP00000029640.3, ENSRNOT00000031231.7
      Conserved Domains (1) summary
      cl21543
      Location:448598
      MMPL; MMPL family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      126216194..126231724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234756.5XP_006234818.1  protein dispatched homolog 2 isoform X1

      See identical proteins and their annotated locations for XP_006234818.1

      UniProtKB/TrEMBL
      A0A8I6G3K8, A6HPC5, A6HPC6, D3ZBZ6
      Conserved Domains (1) summary
      cl21543
      Location:448598
      MMPL; MMPL family