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    Cdk2 cyclin dependent kinase 2 [ Rattus rattus (black rat) ]

    Gene ID: 116906352, updated on 18-Mar-2024

    Summary

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    Gene symbol
    Cdk2
    Gene description
    cyclin dependent kinase 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus rattus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Orthologs
    human mouse all
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    Genomic context

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    See Cdk2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    100 current Rrattus_CSIRO_v1 (GCF_011064425.1) 1 NC_046154.1 (156174352..156182293, complement)

    Chromosome 1 - NC_046154.1Genomic Context describing neighboring genes Neighboring gene sulfite oxidase Neighboring gene RAB5B, member RAS oncogene family Neighboring gene premelanosome protein Neighboring gene diacylglycerol kinase alpha Neighboring gene ragulator complex protein LAMTOR2-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_046154.1 Chromosome 1 Reference Rrattus_CSIRO_v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A variant form of cyclin-dependent kinase 2 (Cdk2) in a malignantly transformed rat thyroid (FRTL-Tc) cell line. Kotani S, et al. Oncogene, 1995 Feb 16. PMID 7862443
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of G2/M transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cyclin-dependent protein kinase holoenzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 2
    Names
    cyclin dependent kinase 2-alpha
    cyclin dependent kinase 2-beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Rattus rattus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rrattus_CSIRO_v1 Primary Assembly

    Genomic

    1. NC_046154.1 Reference Rrattus_CSIRO_v1 Primary Assembly

      Range
      156174352..156182293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032909216.1 → XP_032765107.1  cyclin-dependent kinase 2 isoform X2

      UniProtKB/TrEMBL
      Q63700
      Conserved Domains (1) summary
      cd07860
      Location:3 → 286
      STKc_CDK2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase 2 and 3

    2. XM_032909215.1 → XP_032765106.1  cyclin-dependent kinase 2 isoform X1

      UniProtKB/TrEMBL
      Q63700
      Conserved Domains (1) summary
      cd07860
      Location:3 → 334
      STKc_CDK2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase 2 and 3

    3. XM_032909214.1 → XP_032765105.1  cyclin-dependent kinase 2 isoform X1

      UniProtKB/TrEMBL
      Q63700
      Conserved Domains (1) summary
      cd07860
      Location:3 → 334
      STKc_CDK2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase 2 and 3

    RNA

    1. XR_004388647.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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