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    GRIN1 glutamate ionotropic receptor NMDA type subunit 1 [ Macaca nemestrina (pig-tailed macaque) ]

    Gene ID: 105471967, updated on 13-Mar-2024

    Summary

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    Gene symbol
    GRIN1
    Gene description
    glutamate ionotropic receptor NMDA type subunit 1
    See related
    Ensembl:ENSMNEG00000031771
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca nemestrina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GRIN1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012014799.1 (10412414..10443189)

    NW_012014799.1Genomic Context describing neighboring genes Neighboring gene dipeptidyl peptidase 7 Neighboring gene small nucleolar RNA U13 Neighboring gene leucine rich repeat containing 26 Neighboring gene transmembrane protein 210 Neighboring gene anaphase promoting complex subunit 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012014799 Unplaced Scaffold Reference Mnem_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NMDA glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ionotropic glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NMDA selective glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor ionotropic, NMDA 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mnem_1.0

    Genomic

    1. NW_012014799.1 Reference Mnem_1.0

      Range
      10412414..10443189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011724873.2 → XP_011723175.1  glutamate receptor ionotropic, NMDA 1 isoform X10

      UniProtKB/TrEMBL
      A0A2K6BVF5, A0A2K6BVX4
      Related
      ENSMNEP00000015396.1, ENSMNET00000039604.1
      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    2. XM_011724864.2 → XP_011723166.1  glutamate receptor ionotropic, NMDA 1 isoform X1

      UniProtKB/TrEMBL
      A0A2K6BVN0, A0A2K6BVX4
      Related
      ENSMNEP00000015471.1, ENSMNET00000039680.1
      Conserved Domains (6) summary
      cd06379
      Location:8 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:582 → 845
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:42 → 378
      ANF_receptor; Receptor family ligand binding region
      pfam07885
      Location:623 → 677
      Ion_trans_2; Ion channel
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    3. XM_011724865.2 → XP_011723167.1  glutamate receptor ionotropic, NMDA 1 isoform X2

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Conserved Domains (5) summary
      cd06379
      Location:8 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:561 → 824
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:42 → 357
      ANF_receptor; Receptor family ligand binding region
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    4. XM_011724866.2 → XP_011723168.1  glutamate receptor ionotropic, NMDA 1 isoform X3

      UniProtKB/TrEMBL
      A0A2K6BVR1, A0A2K6BVX4
      Related
      ENSMNEP00000015503.1, ENSMNET00000039712.1
      Conserved Domains (6) summary
      cd06379
      Location:8 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:582 → 845
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:42 → 378
      ANF_receptor; Receptor family ligand binding region
      pfam07885
      Location:623 → 677
      Ion_trans_2; Ion channel
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    5. XM_011724868.2 → XP_011723170.1  glutamate receptor ionotropic, NMDA 1 isoform X5

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    6. XM_011724870.2 → XP_011723172.1  glutamate receptor ionotropic, NMDA 1 isoform X7

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    7. XM_011724867.2 → XP_011723169.1  glutamate receptor ionotropic, NMDA 1 isoform X4

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Conserved Domains (5) summary
      cd06379
      Location:8 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:582 → 845
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:42 → 378
      ANF_receptor; Receptor family ligand binding region
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    8. XM_011724872.2 → XP_011723174.1  glutamate receptor ionotropic, NMDA 1 isoform X9

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Conserved Domains (3) summary
      cd13719
      Location:395 → 799
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06379
      Location:25 → 383
      PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      pfam10562
      Location:835 → 863
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    9. XM_011724869.2 → XP_011723171.1  glutamate receptor ionotropic, NMDA 1 isoform X6

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Related
      ENSMNEP00000015571.1, ENSMNET00000039780.1
      Conserved Domains (6) summary
      cd06379
      Location:8 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:582 → 845
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:42 → 378
      ANF_receptor; Receptor family ligand binding region
      pfam07885
      Location:623 → 677
      Ion_trans_2; Ion channel
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    10. XM_011724871.2 → XP_011723173.1  glutamate receptor ionotropic, NMDA 1 isoform X8

      UniProtKB/TrEMBL
      A0A2K6BVX4
      Conserved Domains (5) summary
      cd06379
      Location:8 → 404
      PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
      cd13719
      Location:416 → 820
      PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam00060
      Location:582 → 845
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:42 → 378
      ANF_receptor; Receptor family ligand binding region
      pfam10562
      Location:856 → 884
      CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

    RNA

    1. XR_981418.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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