ProfileGDS5242 / 8000823
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 98% 98% 95% 95% 94% 89% 98% 94% 96% 95% 89% 66% 71% 68% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 18.526298
GSM1248749naïve B cells CD40L/IL-21; donor 18.684298
GSM1248746naïve B cells CD40L alone; donor 26.904595
GSM1248750naïve B cells CD40L/IL-21; donor 27.049395
GSM1248747naïve B cells CD40L alone; donor 36.099594
GSM1248751naïve B cells CD40L/IL-21; donor 35.703189
GSM1248748naïve B cells CD40L alone; donor 47.734598
GSM1248752naïve B cells CD40L/IL-21; donor 46.711894
GSM1248753naïve B cells CD40L alone; AD-HIES pt 16.403196
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 16.459595
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.75589
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.631766
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.93971
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.829168