ProfileGDS5242 / 8003283
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 78% 74% 65% 62% 34% 48% 58% 77% 40% 63% 78% 77% 60% 80% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 15.448178
GSM1248749naïve B cells CD40L/IL-21; donor 15.234374
GSM1248746naïve B cells CD40L alone; donor 24.652265
GSM1248750naïve B cells CD40L/IL-21; donor 24.508262
GSM1248747naïve B cells CD40L alone; donor 33.769634
GSM1248751naïve B cells CD40L/IL-21; donor 34.187248
GSM1248748naïve B cells CD40L alone; donor 44.334958
GSM1248752naïve B cells CD40L/IL-21; donor 45.165977
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.956540
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.639563
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.189178
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.023877
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.589460
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 35.243980