ProfileGDS5242 / 8018906
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 88% 81% 95% 92% 98% 98% 96% 92% 97% 96% 98% 99% 99% 98% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.132288
GSM1248749naïve B cells CD40L/IL-21; donor 15.701981
GSM1248746naïve B cells CD40L alone; donor 26.77895
GSM1248750naïve B cells CD40L/IL-21; donor 26.578692
GSM1248747naïve B cells CD40L alone; donor 37.281198
GSM1248751naïve B cells CD40L/IL-21; donor 37.446598
GSM1248748naïve B cells CD40L alone; donor 46.945396
GSM1248752naïve B cells CD40L/IL-21; donor 46.411292
GSM1248753naïve B cells CD40L alone; AD-HIES pt 16.957797
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 16.604196
GSM1248754naïve B cells CD40L alone; AD-HIES pt 27.541698
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 27.535599
GSM1248755naïve B cells CD40L alone; AD-HIES pt 38.036699
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 37.299898