ProfileGDS5242 / 8035648
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 52% 48% 66% 59% 86% 71% 60% 59% 72% 72% 80% 59% 90% 85% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.050452
GSM1248749naïve B cells CD40L/IL-21; donor 13.82348
GSM1248746naïve B cells CD40L alone; donor 24.714866
GSM1248750naïve B cells CD40L/IL-21; donor 24.395259
GSM1248747naïve B cells CD40L alone; donor 35.430486
GSM1248751naïve B cells CD40L/IL-21; donor 34.900371
GSM1248748naïve B cells CD40L alone; donor 44.422460
GSM1248752naïve B cells CD40L/IL-21; donor 44.415559
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.832472
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.931872
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.257380
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.447359
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.719590
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 35.452785