ProfileGDS5242 / 8094717
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 62% 55% 10% 13% 6% 12% 9% 25% 13% 8% 8% 9% 5% 12% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.539562
GSM1248749naïve B cells CD40L/IL-21; donor 14.179755
GSM1248746naïve B cells CD40L alone; donor 22.061310
GSM1248750naïve B cells CD40L/IL-21; donor 22.235713
GSM1248747naïve B cells CD40L alone; donor 32.07386
GSM1248751naïve B cells CD40L/IL-21; donor 32.476412
GSM1248748naïve B cells CD40L alone; donor 42.119
GSM1248752naïve B cells CD40L/IL-21; donor 43.015425
GSM1248753naïve B cells CD40L alone; AD-HIES pt 12.784713
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 12.01358
GSM1248754naïve B cells CD40L alone; AD-HIES pt 22.05368
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 22.73529
GSM1248755naïve B cells CD40L alone; AD-HIES pt 31.90225
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 32.529512