ProfileGDS5242 / 8122259
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 50% 64% 90% 79% 98% 93% 94% 78% 97% 94% 93% 97% 98% 97% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.963950
GSM1248749naïve B cells CD40L/IL-21; donor 14.64564
GSM1248746naïve B cells CD40L alone; donor 26.00190
GSM1248750naïve B cells CD40L/IL-21; donor 25.371479
GSM1248747naïve B cells CD40L alone; donor 37.143598
GSM1248751naïve B cells CD40L/IL-21; donor 36.133793
GSM1248748naïve B cells CD40L alone; donor 46.48494
GSM1248752naïve B cells CD40L/IL-21; donor 45.215278
GSM1248753naïve B cells CD40L alone; AD-HIES pt 16.749497
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 16.256794
GSM1248754naïve B cells CD40L alone; AD-HIES pt 26.130493
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 26.483197
GSM1248755naïve B cells CD40L alone; AD-HIES pt 37.42698
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 36.989197