ProfileGDS5242 / 8171203
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 37% 38% 49% 47% 80% 71% 76% 52% 66% 65% 51% 72% 86% 72% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.382537
GSM1248749naïve B cells CD40L/IL-21; donor 13.356138
GSM1248746naïve B cells CD40L alone; donor 24.090649
GSM1248750naïve B cells CD40L/IL-21; donor 23.916647
GSM1248747naïve B cells CD40L alone; donor 35.121980
GSM1248751naïve B cells CD40L/IL-21; donor 34.885471
GSM1248748naïve B cells CD40L alone; donor 45.028776
GSM1248752naïve B cells CD40L/IL-21; donor 44.178752
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.651466
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.688265
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.253651
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.849472
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.507386
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.932472