ProfileGDS5420 / 1555480_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 46% 43% 30% 33% 47% 36% 41% 52% 43% 36% 35% 49% 51% 48% 45% 46% 43% 41% 54% 38% 46% 26% 40% 45% 44% 43% 48% 48% 43% 45% 54% 46% 47% 28% 42% 49% 43% 46% 49% 43% 37% 35% 11% 24% 32% 30% 23% 35% 30% 30% 32% 36% 48% 38% 46% 51% 37% 47% 38% 47% 48% 43% 40% 28% 44% 30% 32% 10% 42% 24% 48% 31% 50% 43% 45% 45% 39% 19% 29% 45% 29% 32% 43% 37% 29% 33% 45% 57% 24% 45% 37% 47% 44% 36% 45% 35% 32% 40% 34% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose130.2146
GSM1296119B_lesional_pre-dose115.6543
GSM1296076C_lesional_pre-dose48.5230
GSM1296092D_lesional_pre-dose51.2533
GSM1296103E_lesional_pre-dose142.0147
GSM1296078F_lesional_pre-dose65.236
GSM1296107G_lesional_pre-dose104.8641
GSM1296109H_lesional_pre-dose210.4352
GSM1296080I_lesional_pre-dose97.3543
GSM1296090J_lesional_pre-dose65.136
GSM1296074K_lesional_pre-dose56.8135
GSM1296111L_lesional_pre-dose174.9249
GSM1296099M_lesional_pre-dose185.7251
GSM1296086O_lesional_pre-dose138.3348
GSM1296117P_lesional_pre-dose137.3745
GSM1296113Q_lesional_pre-dose156.7446
GSM1296096R_lesional_pre-dose110.0943
GSM1296105S_lesional_pre-dose101.1441
GSM1296098T_lesional_pre-dose223.3154
GSM1296101U_lesional_pre-dose85.2838
GSM1296121V_lesional_pre-dose140.9246
GSM1296088W_lesional_pre-dose34.4626
GSM1296082X_lesional_pre-dose82.5440
GSM1296115Y_lesional_pre-dose136.7145
GSM1296084Z_lesional_pre-dose11844
GSM1296072B_lesional_day8117.9143
GSM1296069L_lesional_day8174.2548
GSM1296071P_lesional_day8172.5448
GSM1296070Y_lesional_day8134.7343
GSM1296073V_lesional_day8125.2345
GSM1296034A_lesional_day15241.6954
GSM1296041G_lesional_day15139.8746
GSM1296035R_lesional_day15138.3847
GSM1296038U_lesional_day1539.3928
GSM1296047B_lesional_day15116.4342
GSM1296039E_lesional_day15156.5949
GSM1296042H_lesional_day15129.8243
GSM1296043L_lesional_day15158.6746
GSM1296037M_lesional_day15171.3649
GSM1296046P_lesional_day15133.3743
GSM1296044Q_lesional_day1589.3437
GSM1296045Y_lesional_day1581.9935
GSM1296025C_lesional_day1512.4911
GSM1296033D_lesional_day1530.0924
GSM1296027I_lesional_day1545.7232
GSM1296032J_lesional_day1546.5630
GSM1296024K_lesional_day1527.9923
GSM1296031W_lesional_day1570.6835
GSM1296028X_lesional_day1544.3530
GSM1296029Z_lesional_day1546.1330
GSM1296026F_lesional_day1555.2732
GSM1296030O_lesional_day1558.4136
GSM1296040S_lesional_day15154.1348
GSM1296036T_lesional_day1584.9538
GSM1296048V_lesional_day15144.5346
GSM1296059A_lesional_day43179.8351
GSM1296066G_lesional_day4387.837
GSM1296060R_lesional_day43138.5947
GSM1296063U_lesional_day4384.7138
GSM1296064E_lesional_day43138.1247
GSM1296067H_lesional_day43169.748
GSM1296062M_lesional_day43110.1343
GSM1296068Q_lesional_day43113.3840
GSM1296050C_lesional_day4344.7628
GSM1296057D_lesional_day43121.3844
GSM1296052I_lesional_day4340.1130
GSM1296054J_lesional_day4355.732
GSM1296049K_lesional_day4310.7210
GSM1296055W_lesional_day43109.6642
GSM1296053X_lesional_day4330.1424
GSM1296058Z_lesional_day43148.4948
GSM1296051F_lesional_day4348.9431
GSM1296056O_lesional_day43160.3950
GSM1296065S_lesional_day43111.6143
GSM1296061T_lesional_day43132.945
GSM1296095A_non-lesional_pre-dose121.7245
GSM1296120B_non-lesional_pre-dose95.3939
GSM1296077C_non-lesional_pre-dose21.6719
GSM1296093D_non-lesional_pre-dose45.2729
GSM1296104E_non-lesional_pre-dose124.6645
GSM1296079F_non-lesional_pre-dose44.5229
GSM1296108G_non-lesional_pre-dose60.0332
GSM1296110H_non-lesional_pre-dose132.0843
GSM1296081I_non-lesional_pre-dose66.6937
GSM1296091J_non-lesional_pre-dose40.3329
GSM1296075K_non-lesional_pre-dose54.6233
GSM1296112L_non-lesional_pre-dose153.9645
GSM1296100M_non-lesional_pre-dose271.4557
GSM1296087O_non-lesional_pre-dose26.9524
GSM1296118P_non-lesional_pre-dose149.6645
GSM1296114Q_non-lesional_pre-dose88.9637
GSM1296097R_non-lesional_pre-dose143.0647
GSM1296106S_non-lesional_pre-dose130.9244
GSM1296102U_non-lesional_pre-dose73.4836
GSM1296122V_non-lesional_pre-dose135.7645
GSM1296089W_non-lesional_pre-dose74.1135
GSM1296083X_non-lesional_pre-dose50.7832
GSM1296116Y_non-lesional_pre-dose110.5240
GSM1296085Z_non-lesional_pre-dose60.5234