ProfileGDS5420 / 1556990_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 74% 69% 71% 62% 65% 69% 76% 73% 57% 62% 66% 75% 72% 62% 75% 79% 71% 59% 77% 70% 74% 59% 67% 78% 62% 73% 75% 71% 73% 71% 65% 77% 68% 68% 72% 72% 76% 76% 63% 77% 79% 72% 53% 61% 50% 46% 52% 55% 51% 51% 53% 45% 68% 69% 70% 71% 80% 70% 68% 73% 65% 60% 75% 54% 66% 55% 52% 51% 60% 48% 59% 60% 70% 71% 68% 79% 70% 52% 57% 73% 53% 74% 82% 55% 60% 61% 75% 61% 50% 70% 81% 69% 76% 62% 55% 60% 57% 77% 49% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose762.4174
GSM1296119B_lesional_pre-dose538.6169
GSM1296076C_lesional_pre-dose601.1371
GSM1296092D_lesional_pre-dose335.4162
GSM1296103E_lesional_pre-dose434.2265
GSM1296078F_lesional_pre-dose509.0669
GSM1296107G_lesional_pre-dose812.2476
GSM1296109H_lesional_pre-dose707.7173
GSM1296080I_lesional_pre-dose25457
GSM1296090J_lesional_pre-dose349.162
GSM1296074K_lesional_pre-dose419.2166
GSM1296111L_lesional_pre-dose778.7875
GSM1296099M_lesional_pre-dose648.0572
GSM1296086O_lesional_pre-dose339.8262
GSM1296117P_lesional_pre-dose761.2275
GSM1296113Q_lesional_pre-dose974.0279
GSM1296096R_lesional_pre-dose624.8871
GSM1296105S_lesional_pre-dose304.2559
GSM1296098T_lesional_pre-dose901.4477
GSM1296101U_lesional_pre-dose593.0270
GSM1296121V_lesional_pre-dose714.1674
GSM1296088W_lesional_pre-dose288.1459
GSM1296082X_lesional_pre-dose463.8367
GSM1296115Y_lesional_pre-dose939.3278
GSM1296084Z_lesional_pre-dose360.3262
GSM1296072B_lesional_day8687.4273
GSM1296069L_lesional_day8767.2775
GSM1296071P_lesional_day8610.6271
GSM1296070Y_lesional_day8673.0773
GSM1296073V_lesional_day859571
GSM1296034A_lesional_day15443.1565
GSM1296041G_lesional_day15873.4977
GSM1296035R_lesional_day15518.9968
GSM1296038U_lesional_day15505.0468
GSM1296047B_lesional_day15635.0672
GSM1296039E_lesional_day15626.0772
GSM1296042H_lesional_day15820.4576
GSM1296043L_lesional_day15807.3476
GSM1296037M_lesional_day15390.5363
GSM1296046P_lesional_day15874.3977
GSM1296044Q_lesional_day15967.9779
GSM1296045Y_lesional_day15634.7572
GSM1296025C_lesional_day15203.8153
GSM1296033D_lesional_day15344.3261
GSM1296027I_lesional_day15159.2250
GSM1296032J_lesional_day15136.2446
GSM1296024K_lesional_day15189.5652
GSM1296031W_lesional_day15240.9155
GSM1296028X_lesional_day15178.9851
GSM1296029Z_lesional_day15180.4951
GSM1296026F_lesional_day15194.8953
GSM1296030O_lesional_day15107.7545
GSM1296040S_lesional_day15517.9668
GSM1296036T_lesional_day15576.7369
GSM1296048V_lesional_day15566.2570
GSM1296059A_lesional_day43623.3371
GSM1296066G_lesional_day431003.9780
GSM1296060R_lesional_day43572.7270
GSM1296063U_lesional_day43493.8368
GSM1296064E_lesional_day43657.0973
GSM1296067H_lesional_day43450.865
GSM1296062M_lesional_day43324.2960
GSM1296068Q_lesional_day43782.1775
GSM1296050C_lesional_day43212.9854
GSM1296057D_lesional_day43450.2266
GSM1296052I_lesional_day43214.255
GSM1296054J_lesional_day43204.6952
GSM1296049K_lesional_day43178.9551
GSM1296055W_lesional_day43335.960
GSM1296053X_lesional_day43148.6448
GSM1296058Z_lesional_day43303.7759
GSM1296051F_lesional_day43304.4760
GSM1296056O_lesional_day43579.7670
GSM1296065S_lesional_day43629.9971
GSM1296061T_lesional_day43527.0368
GSM1296095A_non-lesional_pre-dose987.5979
GSM1296120B_non-lesional_pre-dose565.5470
GSM1296077C_non-lesional_pre-dose191.0552
GSM1296093D_non-lesional_pre-dose273.557
GSM1296104E_non-lesional_pre-dose687.4873
GSM1296079F_non-lesional_pre-dose201.4253
GSM1296108G_non-lesional_pre-dose712.6474
GSM1296110H_non-lesional_pre-dose1156.2882
GSM1296081I_non-lesional_pre-dose224.3355
GSM1296091J_non-lesional_pre-dose301.3660
GSM1296075K_non-lesional_pre-dose314.0761
GSM1296112L_non-lesional_pre-dose785.8575
GSM1296100M_non-lesional_pre-dose340.1961
GSM1296087O_non-lesional_pre-dose147.9450
GSM1296118P_non-lesional_pre-dose575.2870
GSM1296114Q_non-lesional_pre-dose1116.0181
GSM1296097R_non-lesional_pre-dose532.9469
GSM1296106S_non-lesional_pre-dose847.3976
GSM1296102U_non-lesional_pre-dose378.7162
GSM1296122V_non-lesional_pre-dose245.4355
GSM1296089W_non-lesional_pre-dose337.5260
GSM1296083X_non-lesional_pre-dose264.5357
GSM1296116Y_non-lesional_pre-dose875.5377
GSM1296085Z_non-lesional_pre-dose159.5949