ProfileGDS5420 / 1561640_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 70% 77% 66% 56% 64% 73% 79% 69% 53% 62% 59% 79% 71% 61% 77% 76% 73% 68% 71% 67% 78% 63% 64% 79% 59% 78% 76% 79% 77% 74% 61% 79% 68% 71% 79% 72% 79% 84% 65% 83% 78% 77% 56% 53% 53% 53% 51% 62% 57% 52% 63% 49% 64% 68% 74% 64% 79% 68% 70% 72% 76% 60% 76% 66% 68% 56% 56% 55% 69% 50% 57% 65% 62% 74% 62% 73% 79% 55% 56% 75% 56% 82% 80% 42% 63% 63% 80% 67% 52% 77% 78% 74% 76% 62% 74% 69% 49% 80% 55% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose576.9770
GSM1296119B_lesional_pre-dose889.0277
GSM1296076C_lesional_pre-dose420.1566
GSM1296092D_lesional_pre-dose221.1256
GSM1296103E_lesional_pre-dose398.8864
GSM1296078F_lesional_pre-dose667.773
GSM1296107G_lesional_pre-dose997.7679
GSM1296109H_lesional_pre-dose539.2669
GSM1296080I_lesional_pre-dose198.0553
GSM1296090J_lesional_pre-dose334.1662
GSM1296074K_lesional_pre-dose271.1459
GSM1296111L_lesional_pre-dose953.7779
GSM1296099M_lesional_pre-dose614.571
GSM1296086O_lesional_pre-dose307.9361
GSM1296117P_lesional_pre-dose856.1777
GSM1296113Q_lesional_pre-dose809.5276
GSM1296096R_lesional_pre-dose678.2473
GSM1296105S_lesional_pre-dose515.1268
GSM1296098T_lesional_pre-dose626.2671
GSM1296101U_lesional_pre-dose489.9967
GSM1296121V_lesional_pre-dose903.6778
GSM1296088W_lesional_pre-dose362.3963
GSM1296082X_lesional_pre-dose389.364
GSM1296115Y_lesional_pre-dose958.9879
GSM1296084Z_lesional_pre-dose295.659
GSM1296072B_lesional_day8936.2778
GSM1296069L_lesional_day8795.2876
GSM1296071P_lesional_day8983.9479
GSM1296070Y_lesional_day8876.7477
GSM1296073V_lesional_day8700.8874
GSM1296034A_lesional_day15356.3861
GSM1296041G_lesional_day151008.1679
GSM1296035R_lesional_day15503.6168
GSM1296038U_lesional_day15629.3471
GSM1296047B_lesional_day15994.7979
GSM1296039E_lesional_day15621.372
GSM1296042H_lesional_day15985.2779
GSM1296043L_lesional_day151292.8984
GSM1296037M_lesional_day15438.9665
GSM1296046P_lesional_day151221.5783
GSM1296044Q_lesional_day15896.8978
GSM1296045Y_lesional_day15845.7677
GSM1296025C_lesional_day15236.6756
GSM1296033D_lesional_day15212.353
GSM1296027I_lesional_day15191.7953
GSM1296032J_lesional_day15207.1953
GSM1296024K_lesional_day15173.5951
GSM1296031W_lesional_day15373.0562
GSM1296028X_lesional_day15257.6457
GSM1296029Z_lesional_day15190.0952
GSM1296026F_lesional_day15363.5463
GSM1296030O_lesional_day15140.9749
GSM1296040S_lesional_day15424.4564
GSM1296036T_lesional_day15531.6668
GSM1296048V_lesional_day15720.474
GSM1296059A_lesional_day43403.0364
GSM1296066G_lesional_day43970.6779
GSM1296060R_lesional_day43526.8368
GSM1296063U_lesional_day4355270
GSM1296064E_lesional_day43640.572
GSM1296067H_lesional_day43835.7476
GSM1296062M_lesional_day43338.4560
GSM1296068Q_lesional_day43814.1376
GSM1296050C_lesional_day43450.9566
GSM1296057D_lesional_day43507.6168
GSM1296052I_lesional_day43242.5356
GSM1296054J_lesional_day43264.1756
GSM1296049K_lesional_day43233.3255
GSM1296055W_lesional_day43552.7269
GSM1296053X_lesional_day43173.7850
GSM1296058Z_lesional_day43260.1457
GSM1296051F_lesional_day43415.5165
GSM1296056O_lesional_day43338.4362
GSM1296065S_lesional_day43746.1574
GSM1296061T_lesional_day43370.6762
GSM1296095A_non-lesional_pre-dose683.1373
GSM1296120B_non-lesional_pre-dose954.1479
GSM1296077C_non-lesional_pre-dose231.5955
GSM1296093D_non-lesional_pre-dose270.9756
GSM1296104E_non-lesional_pre-dose771.9175
GSM1296079F_non-lesional_pre-dose234.1756
GSM1296108G_non-lesional_pre-dose1184.0982
GSM1296110H_non-lesional_pre-dose1010.7280
GSM1296081I_non-lesional_pre-dose94.5842
GSM1296091J_non-lesional_pre-dose366.6163
GSM1296075K_non-lesional_pre-dose348.8563
GSM1296112L_non-lesional_pre-dose1033.7380
GSM1296100M_non-lesional_pre-dose511.2567
GSM1296087O_non-lesional_pre-dose168.2952
GSM1296118P_non-lesional_pre-dose851.2277
GSM1296114Q_non-lesional_pre-dose913.7578
GSM1296097R_non-lesional_pre-dose735.5174
GSM1296106S_non-lesional_pre-dose849.1276
GSM1296102U_non-lesional_pre-dose389.9862
GSM1296122V_non-lesional_pre-dose721.0174
GSM1296089W_non-lesional_pre-dose570.3269
GSM1296083X_non-lesional_pre-dose161.8649
GSM1296116Y_non-lesional_pre-dose1012.8580
GSM1296085Z_non-lesional_pre-dose235.8355