ProfileGDS5420 / 201259_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 62% 89% 93% 92% 80% 91% 88% 84% 56% 92% 91% 92% 88% 90% 92% 91% 86% 60% 57% 64% 88% 81% 93% 91% 81% 85% 90% 83% 87% 89% 38% 91% 86% 84% 82% 92% 88% 86% 79% 87% 86% 85% 49% 82% 73% 81% 52% 75% 79% 73% 67% 76% 74% 61% 88% 85% 88% 84% 90% 94% 76% 73% 88% 80% 81% 74% 55% 50% 83% 62% 79% 87% 88% 89% 62% 88% 84% 72% 55% 89% 63% 83% 81% 52% 88% 86% 86% 79% 80% 84% 87% 83% 75% 60% 82% 84% 58% 86% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose357.6362
GSM1296119B_lesional_pre-dose1995.8789
GSM1296076C_lesional_pre-dose3003.9293
GSM1296092D_lesional_pre-dose2631.2692
GSM1296103E_lesional_pre-dose1063.9780
GSM1296078F_lesional_pre-dose2696.8691
GSM1296107G_lesional_pre-dose1846.3588
GSM1296109H_lesional_pre-dose1296.6684
GSM1296080I_lesional_pre-dose236.5256
GSM1296090J_lesional_pre-dose2685.3892
GSM1296074K_lesional_pre-dose273191
GSM1296111L_lesional_pre-dose2414.192
GSM1296099M_lesional_pre-dose1790.7188
GSM1296086O_lesional_pre-dose2220.790
GSM1296117P_lesional_pre-dose2486.0192
GSM1296113Q_lesional_pre-dose2111.8791
GSM1296096R_lesional_pre-dose1579.5886
GSM1296105S_lesional_pre-dose321.3460
GSM1296098T_lesional_pre-dose268.1157
GSM1296101U_lesional_pre-dose408.6764
GSM1296121V_lesional_pre-dose1794.0188
GSM1296088W_lesional_pre-dose1127.4981
GSM1296082X_lesional_pre-dose3063.3893
GSM1296115Y_lesional_pre-dose2411.191
GSM1296084Z_lesional_pre-dose1162.781
GSM1296072B_lesional_day81408.5685
GSM1296069L_lesional_day82031.7390
GSM1296071P_lesional_day81246.4183
GSM1296070Y_lesional_day81642.6587
GSM1296073V_lesional_day82136.0789
GSM1296034A_lesional_day1585.3938
GSM1296041G_lesional_day152346.7491
GSM1296035R_lesional_day151658.8886
GSM1296038U_lesional_day151408.0184
GSM1296047B_lesional_day151155.7782
GSM1296039E_lesional_day152674.592
GSM1296042H_lesional_day151800.1588
GSM1296043L_lesional_day151484.0686
GSM1296037M_lesional_day15961.6179
GSM1296046P_lesional_day151650.387
GSM1296044Q_lesional_day151481.5186
GSM1296045Y_lesional_day151377.7185
GSM1296025C_lesional_day15155.7349
GSM1296033D_lesional_day151187.3382
GSM1296027I_lesional_day15710.5973
GSM1296032J_lesional_day151118.0481
GSM1296024K_lesional_day15189.3852
GSM1296031W_lesional_day15783.1175
GSM1296028X_lesional_day151010.0779
GSM1296029Z_lesional_day15710.9173
GSM1296026F_lesional_day15475.9267
GSM1296030O_lesional_day15820.0676
GSM1296040S_lesional_day15727.5774
GSM1296036T_lesional_day15364.8861
GSM1296048V_lesional_day151789.4288
GSM1296059A_lesional_day431451.0285
GSM1296066G_lesional_day431830.988
GSM1296060R_lesional_day431342.5184
GSM1296063U_lesional_day432114.9790
GSM1296064E_lesional_day433715.7794
GSM1296067H_lesional_day43838.6276
GSM1296062M_lesional_day43694.1873
GSM1296068Q_lesional_day431646.988
GSM1296050C_lesional_day431075.6180
GSM1296057D_lesional_day431115.881
GSM1296052I_lesional_day43744.5774
GSM1296054J_lesional_day43246.4155
GSM1296049K_lesional_day43171.7350
GSM1296055W_lesional_day431271.8783
GSM1296053X_lesional_day43362.3162
GSM1296058Z_lesional_day431041.7779
GSM1296051F_lesional_day431773.1587
GSM1296056O_lesional_day431916.0588
GSM1296065S_lesional_day431922.0189
GSM1296061T_lesional_day43374.3962
GSM1296095A_non-lesional_pre-dose1940.1188
GSM1296120B_non-lesional_pre-dose133984
GSM1296077C_non-lesional_pre-dose644.572
GSM1296093D_non-lesional_pre-dose253.9555
GSM1296104E_non-lesional_pre-dose2119.2389
GSM1296079F_non-lesional_pre-dose362.7963
GSM1296108G_non-lesional_pre-dose1300.0383
GSM1296110H_non-lesional_pre-dose1090.5881
GSM1296081I_non-lesional_pre-dose177.252
GSM1296091J_non-lesional_pre-dose1819.2288
GSM1296075K_non-lesional_pre-dose1652.2186
GSM1296112L_non-lesional_pre-dose1425.6286
GSM1296100M_non-lesional_pre-dose960.1979
GSM1296087O_non-lesional_pre-dose1064.4680
GSM1296118P_non-lesional_pre-dose1355.8584
GSM1296114Q_non-lesional_pre-dose1603.5787
GSM1296097R_non-lesional_pre-dose1306.5383
GSM1296106S_non-lesional_pre-dose786.275
GSM1296102U_non-lesional_pre-dose332.760
GSM1296122V_non-lesional_pre-dose1172.8382
GSM1296089W_non-lesional_pre-dose1313.6384
GSM1296083X_non-lesional_pre-dose282.458
GSM1296116Y_non-lesional_pre-dose1520.1886
GSM1296085Z_non-lesional_pre-dose543.269