ProfileGDS5420 / 226756_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 56% 74% 74% 65% 63% 74% 69% 65% 62% 76% 79% 70% 64% 74% 70% 71% 67% 69% 49% 64% 67% 67% 64% 72% 69% 73% 84% 77% 73% 71% 59% 68% 76% 70% 72% 68% 71% 75% 67% 74% 71% 76% 79% 66% 78% 71% 83% 79% 68% 78% 83% 74% 65% 56% 76% 61% 69% 69% 77% 67% 79% 69% 73% 83% 77% 74% 65% 82% 83% 70% 77% 80% 76% 67% 60% 61% 71% 79% 65% 64% 81% 71% 71% 77% 62% 79% 76% 67% 75% 73% 73% 69% 73% 66% 80% 72% 84% 72% 68% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose252.7956
GSM1296119B_lesional_pre-dose707.8174
GSM1296076C_lesional_pre-dose711.7174
GSM1296092D_lesional_pre-dose402.0365
GSM1296103E_lesional_pre-dose375.9263
GSM1296078F_lesional_pre-dose717.7574
GSM1296107G_lesional_pre-dose536.6869
GSM1296109H_lesional_pre-dose429.2565
GSM1296080I_lesional_pre-dose358.2562
GSM1296090J_lesional_pre-dose846.4676
GSM1296074K_lesional_pre-dose1000.7979
GSM1296111L_lesional_pre-dose563.8170
GSM1296099M_lesional_pre-dose419.6664
GSM1296086O_lesional_pre-dose739.9574
GSM1296117P_lesional_pre-dose561.1570
GSM1296113Q_lesional_pre-dose616.5771
GSM1296096R_lesional_pre-dose478.5767
GSM1296105S_lesional_pre-dose564.2369
GSM1296098T_lesional_pre-dose165.5849
GSM1296101U_lesional_pre-dose417.864
GSM1296121V_lesional_pre-dose468.1467
GSM1296088W_lesional_pre-dose469.7367
GSM1296082X_lesional_pre-dose370.464
GSM1296115Y_lesional_pre-dose647.872
GSM1296084Z_lesional_pre-dose529.469
GSM1296072B_lesional_day8685.4873
GSM1296069L_lesional_day81284.2384
GSM1296071P_lesional_day8882.5477
GSM1296070Y_lesional_day8673.1673
GSM1296073V_lesional_day8589.7971
GSM1296034A_lesional_day15324.859
GSM1296041G_lesional_day15509.8668
GSM1296035R_lesional_day15844.6576
GSM1296038U_lesional_day15557.8570
GSM1296047B_lesional_day15652.8372
GSM1296039E_lesional_day1548968
GSM1296042H_lesional_day15604.4371
GSM1296043L_lesional_day15753.3775
GSM1296037M_lesional_day15493.9967
GSM1296046P_lesional_day15725.7574
GSM1296044Q_lesional_day15601.0971
GSM1296045Y_lesional_day15832.676
GSM1296025C_lesional_day151036.0979
GSM1296033D_lesional_day15463.2466
GSM1296027I_lesional_day15948.1278
GSM1296032J_lesional_day15637.1971
GSM1296024K_lesional_day151311.5183
GSM1296031W_lesional_day151020.0479
GSM1296028X_lesional_day15507.6568
GSM1296029Z_lesional_day15931.0478
GSM1296026F_lesional_day151261.4683
GSM1296030O_lesional_day15759.8774
GSM1296040S_lesional_day15441.6665
GSM1296036T_lesional_day15266.5956
GSM1296048V_lesional_day15830.4276
GSM1296059A_lesional_day43340.5861
GSM1296066G_lesional_day43555.7669
GSM1296060R_lesional_day43556.8169
GSM1296063U_lesional_day43876.6377
GSM1296064E_lesional_day43470.0867
GSM1296067H_lesional_day43969.1279
GSM1296062M_lesional_day43558.0869
GSM1296068Q_lesional_day43675.973
GSM1296050C_lesional_day431332.3183
GSM1296057D_lesional_day43882.6777
GSM1296052I_lesional_day43744.374
GSM1296054J_lesional_day43436.3465
GSM1296049K_lesional_day431177.1882
GSM1296055W_lesional_day431251.9183
GSM1296053X_lesional_day43584.270
GSM1296058Z_lesional_day43880.9277
GSM1296051F_lesional_day431104.7380
GSM1296056O_lesional_day43802.0876
GSM1296065S_lesional_day43490.2567
GSM1296061T_lesional_day43331.260
GSM1296095A_non-lesional_pre-dose336.0161
GSM1296120B_non-lesional_pre-dose625.0871
GSM1296077C_non-lesional_pre-dose1005.9379
GSM1296093D_non-lesional_pre-dose439.3965
GSM1296104E_non-lesional_pre-dose387.7464
GSM1296079F_non-lesional_pre-dose1142.681
GSM1296108G_non-lesional_pre-dose607.3471
GSM1296110H_non-lesional_pre-dose606.971
GSM1296081I_non-lesional_pre-dose885.5477
GSM1296091J_non-lesional_pre-dose357.7262
GSM1296075K_non-lesional_pre-dose1029.3179
GSM1296112L_non-lesional_pre-dose820.6976
GSM1296100M_non-lesional_pre-dose507.4367
GSM1296087O_non-lesional_pre-dose808.8375
GSM1296118P_non-lesional_pre-dose708.0373
GSM1296114Q_non-lesional_pre-dose688.1373
GSM1296097R_non-lesional_pre-dose536.0669
GSM1296106S_non-lesional_pre-dose690.0173
GSM1296102U_non-lesional_pre-dose484.6266
GSM1296122V_non-lesional_pre-dose1026.0480
GSM1296089W_non-lesional_pre-dose671.4672
GSM1296083X_non-lesional_pre-dose1333.8984
GSM1296116Y_non-lesional_pre-dose648.4672
GSM1296085Z_non-lesional_pre-dose505.9368