ProfileGDS5420 / 235650_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 44% 37% 47% 37% 29% 47% 44% 41% 32% 38% 39% 48% 42% 38% 44% 41% 45% 47% 43% 41% 45% 39% 38% 39% 44% 44% 45% 44% 42% 43% 45% 42% 43% 41% 38% 32% 49% 47% 41% 35% 42% 44% 40% 31% 49% 37% 43% 47% 31% 48% 42% 45% 22% 35% 44% 41% 42% 45% 45% 34% 48% 33% 47% 41% 46% 52% 35% 54% 50% 50% 54% 40% 44% 47% 46% 34% 44% 44% 48% 27% 45% 44% 55% 44% 23% 46% 52% 38% 46% 46% 37% 48% 39% 35% 45% 47% 48% 49% 49% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose120.3344
GSM1296119B_lesional_pre-dose82.8237
GSM1296076C_lesional_pre-dose128.6847
GSM1296092D_lesional_pre-dose64.0737
GSM1296103E_lesional_pre-dose43.0829
GSM1296078F_lesional_pre-dose127.8947
GSM1296107G_lesional_pre-dose125.7144
GSM1296109H_lesional_pre-dose105.9641
GSM1296080I_lesional_pre-dose49.9932
GSM1296090J_lesional_pre-dose73.0838
GSM1296074K_lesional_pre-dose74.6139
GSM1296111L_lesional_pre-dose168.0648
GSM1296099M_lesional_pre-dose105.0342
GSM1296086O_lesional_pre-dose73.8238
GSM1296117P_lesional_pre-dose131.8644
GSM1296113Q_lesional_pre-dose118.3541
GSM1296096R_lesional_pre-dose123.0245
GSM1296105S_lesional_pre-dose152.1747
GSM1296098T_lesional_pre-dose119.8743
GSM1296101U_lesional_pre-dose100.0341
GSM1296121V_lesional_pre-dose128.7345
GSM1296088W_lesional_pre-dose83.539
GSM1296082X_lesional_pre-dose71.3638
GSM1296115Y_lesional_pre-dose92.3439
GSM1296084Z_lesional_pre-dose121.3344
GSM1296072B_lesional_day8130.644
GSM1296069L_lesional_day8145.6445
GSM1296071P_lesional_day8143.244
GSM1296070Y_lesional_day8126.7342
GSM1296073V_lesional_day8112.0443
GSM1296034A_lesional_day15139.445
GSM1296041G_lesional_day15113.442
GSM1296035R_lesional_day15107.3343
GSM1296038U_lesional_day1599.3641
GSM1296047B_lesional_day1595.0538
GSM1296039E_lesional_day1554.8132
GSM1296042H_lesional_day15173.0649
GSM1296043L_lesional_day15159.7847
GSM1296037M_lesional_day15104.5341
GSM1296046P_lesional_day1580.8135
GSM1296044Q_lesional_day15124.0942
GSM1296045Y_lesional_day15137.6744
GSM1296025C_lesional_day1587.7740
GSM1296033D_lesional_day1549.8531
GSM1296027I_lesional_day15147.8549
GSM1296032J_lesional_day1576.1937
GSM1296024K_lesional_day15104.9443
GSM1296031W_lesional_day15151.4747
GSM1296028X_lesional_day1548.7331
GSM1296029Z_lesional_day15154.6648
GSM1296026F_lesional_day1599.942
GSM1296030O_lesional_day15105.9645
GSM1296040S_lesional_day1528.5622
GSM1296036T_lesional_day1572.3835
GSM1296048V_lesional_day15128.8744
GSM1296059A_lesional_day4392.341
GSM1296066G_lesional_day43116.6942
GSM1296060R_lesional_day43125.545
GSM1296063U_lesional_day43129.9745
GSM1296064E_lesional_day4360.4634
GSM1296067H_lesional_day43169.2648
GSM1296062M_lesional_day4357.1633
GSM1296068Q_lesional_day43171.8447
GSM1296050C_lesional_day43100.3941
GSM1296057D_lesional_day43138.1446
GSM1296052I_lesional_day43185.1152
GSM1296054J_lesional_day4370.1135
GSM1296049K_lesional_day43213.6554
GSM1296055W_lesional_day43179.0550
GSM1296053X_lesional_day43169.1750
GSM1296058Z_lesional_day43221.3854
GSM1296051F_lesional_day4386.4840
GSM1296056O_lesional_day43109.9444
GSM1296065S_lesional_day43151.1647
GSM1296061T_lesional_day43140.6746
GSM1296095A_non-lesional_pre-dose58.5434
GSM1296120B_non-lesional_pre-dose134.1844
GSM1296077C_non-lesional_pre-dose114.0844
GSM1296093D_non-lesional_pre-dose159.5648
GSM1296104E_non-lesional_pre-dose38.927
GSM1296079F_non-lesional_pre-dose118.0645
GSM1296108G_non-lesional_pre-dose130.6144
GSM1296110H_non-lesional_pre-dose260.2355
GSM1296081I_non-lesional_pre-dose110.8544
GSM1296091J_non-lesional_pre-dose27.0923
GSM1296075K_non-lesional_pre-dose125.5846
GSM1296112L_non-lesional_pre-dose226.2652
GSM1296100M_non-lesional_pre-dose82.2238
GSM1296087O_non-lesional_pre-dose112.6646
GSM1296118P_non-lesional_pre-dose153.8646
GSM1296114Q_non-lesional_pre-dose94.0437
GSM1296097R_non-lesional_pre-dose153.148
GSM1296106S_non-lesional_pre-dose92.3539
GSM1296102U_non-lesional_pre-dose69.6335
GSM1296122V_non-lesional_pre-dose140.8245
GSM1296089W_non-lesional_pre-dose148.6847
GSM1296083X_non-lesional_pre-dose155.1648
GSM1296116Y_non-lesional_pre-dose190.749
GSM1296085Z_non-lesional_pre-dose161.6449