A type of anemia caused by premature destruction of red blood cells (hemolysis).

Epistaxis, or nosebleed, refers to a hemorrhage localized in the nose.

A reduction in the number of circulating thrombocytes.

Prolongation of the time taken for a standardized skin cut of fixed depth and length to stop bleeding.

An elevation in the number of reticulocytes (immature erythrocytes) in the peripheral blood circulation.

Red blood cell distribution width (RDW) is a simple parameter of the standard full blood count and a measure of heterogeneity in the size of circulating erythrocytes. It is provided by automated hematology analyzers and it reflects the range of the red cell size. It is calculated by dividing the standard deviation of erythrocyte volume by the mean corpuscular volume (MCV) and multiplied by 100 to convert to a percentage.

Average platelet volume above the upper limit of the normal reference interval.

A reduced number of platelet alpha granules.

Abnormal increased size of the spleen.

Petechiae are pinpoint-sized reddish/purple spots, resembling a rash, that appear just under the skin or a mucous membrane when capillaries have ruptured and some superficial bleeding into the skin has happened. This term refers to an abnormally increased susceptibility to developing petechiae.

An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels. This term refers to an abnormally increased susceptibility to bruising. The corresponding phenotypic abnormality is generally elicited on medical history as a report of frequent ecchymoses or bruising without adequate trauma.