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Clofibrate
A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Year introduced: 1972(1969)
Anticholesteremic Agents
Substances used to lower plasma CHOLESTEROL levels.
Year introduced: 1966(1964)
Hypolipidemic Agents
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
Year introduced: 2010(1966)
Hydrocarbons, Aromatic
Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.
Year introduced: 1998
Acids, Acyclic
Carboxylic acids that have open-chain molecular structures as opposed to ring-shaped structures.
Benzene Derivatives
Organic compounds derived from BENZENE.
Year introduced: 1968
Butyrates
Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure.
Year introduced: 1963
Carboxylic Acids
Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.
Year introduced: 1973(1971)
Clofibric Acid
An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
Year introduced: 1991(1980)
Ethers
Organic compounds having two alkyl or aryl groups bonded to an oxygen atom, as in the formula R1–O–R2.
Hydrocarbons
Organic compounds that primarily contain carbon and hydrogen atoms with the carbon atoms forming a linear or circular structure.
Isobutyrates
Aliphatic acids that contain four carbons in a branched-chain configuration. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the 2-carboxypropane structure.
Year introduced: 2011
Hydrocarbons, Cyclic
Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.
Organic Chemicals
A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.
Phenols
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
Phenyl Ethers
Ethers that are linked to a benzene ring structure.
Year introduced: 1974
Fibric Acids
Compounds that either share the structure of fibric acid in their molecular arrangement or are considered variants of the fibric acid structure.
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Year introduced: 1999
Pharmacologic Actions
A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.
Year introduced: 2004(1999)
Molecular Mechanisms of Pharmacological Action
Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY.
Year introduced: 2008(2004)