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Rattus norvegicus integrin alpha FG-GAP repeat containing 1 (Itfg1), mRNA

NCBI Reference Sequence: NM_133557.2

FASTA Graphics 

LOCUS       NM_133557               3407 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus integrin alpha FG-GAP repeat containing 1
            (Itfg1), mRNA.
ACCESSION   NM_133557 XM_346518
VERSION     NM_133557.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3407)
  AUTHORS   Principe,S., Jones,E.E., Kim,Y., Sinha,A., Nyalwidhe,J.O.,
            Brooks,J., Semmes,O.J., Troyer,D.A., Lance,R.S., Kislinger,T. and
            Drake,R.R.
  TITLE     In-depth proteomic analyses of exosomes isolated from expressed
            prostatic secretions in urine
  JOURNAL   Proteomics 13 (10-11), 1667-1671 (2013)
   PUBMED   23533145
REFERENCE   2  (bases 1 to 3407)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   3  (bases 1 to 3407)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085706.1.
            
            On May 23, 2007 this sequence version replaced NM_133557.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085706.1, AF480856.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3407
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p11"
     gene            1..3407
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="integrin alpha FG-GAP repeat containing 1"
                     /db_xref="GeneID:171083"
                     /db_xref="RGD:619898"
     exon            1..348
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    48..50
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="upstream in-frame stop codon"
     CDS             144..1976
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="CDA08-like protein; linkin; integrin-alpha FG-GAP
                     repeat-containing protein 1; T-cell immunomodulatory
                     protein; hypothetical protein CDA08"
                     /codon_start=1
                     /product="T-cell immunomodulatory protein precursor"
                     /protein_id="NP_598241.2"
                     /db_xref="GeneID:171083"
                     /db_xref="RGD:619898"
                     /translation="MAAGLLPSARAVLALLFLGLALLSVGPAPAQALHNVTAELFGGE
                     AWGTLAAFGDLNSDKQTDLFVLRERNDLIVFLADQSAPYFKPKVKVSLKNFSALVTSV
                     VPGDYDGDSQMDVLLTYFPQNHSNNELGAVIFWGQNQTLDPKNMTILNRTFHDQPLIM
                     DFNGDLIPDVFAITNESSQPQILLGGDLSWHPALTTKSKMRDPHSHAFIDLTEDFTAD
                     LFLTTLSASNTFQFEIWENLGGNFSIRSVFEKPKNLVVVGQSAFADFDGDGHMDHLLP
                     GCEDKDCQKSAIYLMRSGTGQWAPVLQDFSNKGTLWGFVPFVHEERPTAIPVPLTLHI
                     GDYNMDGYPDALAILKNTSGSNQQAFLLENVPCNNASCEEVHRMFKVYWDLAGLNLIK
                     DAMVATFFDIYEDGILDIIVLSKGYTKSDVAIHTLKNNFEADAYFVKVIVLSGLCSSD
                     CPRKITPFGVNQPGPYIMYTTVDANGYLKNGSAGQLSQSAHLALQLPYNVLGLGRSAN
                     FLDHLFVGIPRPSGEKSIRKQEWTAIIPNSQLIVIPYPHSVPRSWSAKLYLTPSNIVL
                     LTAVALTGVCVFILAIIAILHWQEKKADDREKRQEAHRFHFDAM"
     sig_peptide     144..239
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
     mat_peptide     240..1973
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /product="T-cell immunomodulatory protein.
                     /id=PRO_0000034356"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8R4E1.1)"
     misc_feature    246..248
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    423..425
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    435..548
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8R4E1.1);
                     Region: FG-GAP 1, atypical"
     misc_feature    510..512
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    555..557
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    576..578
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    591..593
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    600..692
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8R4E1.1);
                     Region: FG-GAP 2, atypical"
     misc_feature    666..668
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    864..866
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    909..1016
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8R4E1.1);
                     Region: FG-GAP 3, atypical"
     misc_feature    1194..1196
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    1248..1250
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    1581..1583
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0007744|PubMed:24090084; propagated from
                     UniProtKB/Swiss-Prot (Q8R4E1.1); glycosylation site"
     misc_feature    1833..1895
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8R4E1.1);
                     transmembrane region"
     exon            349..421
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            422..567
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            568..625
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            626..700
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            701..795
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            796..857
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            858..939
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1034
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1207
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1358
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1467
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..1511
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1590
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1715
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1798
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1916
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
     exon            1917..3385
                     /gene="Itfg1"
                     /gene_synonym="Cda08"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaacagc cccagggcag cgtgagaata caacgagggg ctgcccgtaa gctcgcaccc
       61 cgagtctttt ctcggtcggc cggttgcacg gtgctttgcg gctgccgtca agcgcggcgg
      121 aggccggccg ggccgaaggc gccatggcgg caggcctgct gcctagcgcc agggcggtgc
      181 tggcgctgct gttcttggga ctcgcgctgc tgagcgttgg gcctgctccg gcacaggctc
      241 tacacaatgt cacggccgag ctctttgggg gtgaggcctg gggcaccctg gcggccttcg
      301 gtgacctcaa ctccgacaaa cagacggacc tcttcgtgct gcgggaaaga aatgacttaa
      361 tcgtcttttt ggcagatcag agtgcaccct attttaaacc caaggtaaag gtgtccttga
      421 agaatttcag tgcattggta acaagtgtag tccctggtga ttatgatggg gactcacaaa
      481 tggatgtcct gctcacatat tttccccaaa atcatagcaa caatgaatta ggagctgtta
      541 tcttctgggg acaaaatcaa acattagatc ctaaaaacat gaccatactc aataggactt
      601 ttcatgacca gccactgatt atggacttca acggtgatct aattcctgat gtgtttgcta
      661 tcacaaatga atccagccag ccgcagatac tgttaggagg agatttgtca tggcatcctg
      721 ccttgaccac taagagtaaa atgcgggacc cacattctca tgcatttatt gatctgactg
      781 aagattttac agcagattta ttccttacaa cattgtctgc ctctaatacc ttccagtttg
      841 agatatggga aaatttgggt ggaaacttct ctatccgtag tgtctttgaa aaacctaaaa
      901 atctggtggt ggttggacag tcagcattcg cagactttga tggagatgga cacatggatc
      961 acttgctgcc aggctgtgaa gataaggact gtcagaaaag tgccatttat ttaatgagat
     1021 caggaacagg acagtgggct cctgtgcttc aggattttag caataagggc acactctggg
     1081 gctttgtccc attcgtgcat gaagagcggc caactgcaat tccagttcca ctcacacttc
     1141 acattggaga ctacaacatg gacggctacc ctgatgctct ggccatatta aagaatacat
     1201 ctggaagcaa tcagcaagcc ttcttactgg agaatgtccc gtgcaataat gcgagctgtg
     1261 aggaagtgca ccggatgttc aaagtctact gggacctagc aggcctgaat ctaatcaaag
     1321 acgccatggt tgccaccttt tttgacattt atgaagatgg gatcttggac attatagtcc
     1381 tcagtaaagg atacaccaag agtgatgttg ccatccacac actcaaaaat aactttgaag
     1441 cagatgcgta ttttgttaaa gtcattgttc ttagtggtct atgttctagt gactgtcctc
     1501 gtaagataac accctttgga gtgaatcagc ctggacctta tatcatgtac acaacagtag
     1561 atgcaaatgg gtatctgaaa aatggctcag ctgggcagct tagccagtca gcacacttag
     1621 ctctccagct gccttacaat gtgcttggtt taggccgaag tgccaatttc ctggaccatc
     1681 tttttgttgg cattccccgt ccatctggag agaagtctat aaggaaacaa gagtggacag
     1741 caatcattcc aaattcgcag ctgattgtca tcccataccc tcacagtgtc ccgagaagct
     1801 ggagtgccaa gttgtacctg acaccaagta acattgtcct gctgactgcg gtagccctca
     1861 ccggcgtctg cgtcttcatc ctggcaataa tcgccatttt acactggcag gaaaagaaag
     1921 ctgacgacag ggaaaagcgg caagaagcac atcgcttcca ctttgacgct atgtgattct
     1981 gctttcagtg gtacatcctg gaagtcactt gattagcgaa acactaaact ttgactccta
     2041 gtaaaaaaaa taatggatct gagatattta taaattatgc cttccttgtc aattattgga
     2101 aaatactgaa ataaatatgg cctgcatatc tcataaggtc tgctttaagc actctgtata
     2161 taataaccta gcttctttat tcagtggtac tgagcattct gttcctctgt ggaatgtgtt
     2221 gcatgtgctc tggtatttgt gtttacaatg ttgttagaat tacgatggtg gaaggacatg
     2281 taaataaaaa ctatttaaac aacctggggc caggacattg ttccacctaa attgatcttg
     2341 ctttttatct taaaaatgca cactttctca actatgtggc agataaagtt attcaactaa
     2401 cattcttcac tgcagggcag agctctgagt ggcatggaat gagactaatt agccaggctt
     2461 tggaatctca gtaggacaga ctgccttaga tgcctggttc tacagcttac aactctctga
     2521 atctggctac tgcttagcct ctctgtaagc cgcagtcttg tttatatgat gtggcttata
     2581 tgcctgttca cttgagttat cgtggatgta tactgactga tgcacacagt gatcacttga
     2641 gttatcatgg atgtacactg tctgatgcac atgtgatcac ttgagttatc atgaatgtac
     2701 attgttatat gatgcacatg tgttcacttg agttatcatg gatgtacatt gtctgatgca
     2761 catggtgtac ttagctcagt gcctgagcaa acaggaagtg ttcaccaagc ggaggctgtc
     2821 cttgctcttg ccggtgattt aatctactac tgtatagaat ggatcattat tatagacata
     2881 aggacatact ctttggaaag cttaaattat tggtggtaca tatctcatat aattaatttg
     2941 tttgactagc tatataatac tacccaagag taaatgtatc ctaaaacctg gtacttgaat
     3001 actgatcctt gtacagtgat gtaaatcatt tggtctcttg aaagaaagct gacagaggca
     3061 aactctgggg gtgcaaactg ccgtcacagc tctgctcgca ggacgggaaa gtcagtctca
     3121 gttctcttca gaccacaggg ttcatactat gaactttaca ttgccaaaat tcactttaaa
     3181 attatttaaa ttagagttga ggagagaggt gatattcaga ttactaagac atgctgtggc
     3241 tgtaaactat aaaaattcct ctagaacagt tttgtctgtg ttattttccc cactgcagtt
     3301 cactgaaggg catgtgctcc tttttatttc tatttaagca tgttaatgta tcgtcttaat
     3361 aaatactcct tactgattga aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
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Reference sequence information

  • RefSeq protein product
    See the reference protein sequence for T-cell immunomodulatory protein precursor (NP_598241.2).

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