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NCBI Reference Sequence: NM_001107321.3
FASTA Graphics
LOCUS NM_001107321 2256 bp mRNA linear ROD 31-MAR-2024 DEFINITION Rattus norvegicus HtrA serine peptidase 4 (Htra4), mRNA. ACCESSION NM_001107321 XM_001071971 XM_224963 VERSION NM_001107321.3 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (bases 1 to 2256) AUTHORS Ketteler,R., Sun,Z., Kovacs,K.F., He,W.W. and Seed,B. TITLE A pathway sensor for genome-wide screens of intracellular proteolytic cleavage JOURNAL Genome Biol 9 (4), R64 (2008) PUBMED 18387192 REMARK Publication Status: Online-Only COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAXUCZ010000016.1. On Mar 31, 2024 this sequence version replaced NM_001107321.2. ##Evidence-Data-START## Transcript exon combination :: SRR26643299.59325.1, SRR26643288.56100.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA5760393, SAMN06621351 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-616 JAXUCZ010000016.1 73704255-73704870 617-716 JAXUCZ010000016.1 73705251-73705350 717-921 JAXUCZ010000016.1 73706084-73706288 922-1116 JAXUCZ010000016.1 73709154-73709348 1117-1149 JAXUCZ010000016.1 73709755-73709787 1150-1264 JAXUCZ010000016.1 73711910-73712024 1265-1322 JAXUCZ010000016.1 73712367-73712424 1323-1418 JAXUCZ010000016.1 73712767-73712862 1419-2256 JAXUCZ010000016.1 73716885-73717722 FEATURES Location/Qualifiers source 1..2256 /organism="Rattus norvegicus" /mol_type="mRNA" /strain="BN" /db_xref="taxon:10116" /chromosome="16" /map="16q12.4" gene 1..2256 /gene="Htra4" /gene_synonym="RGD1306242" /note="HtrA serine peptidase 4" /db_xref="GeneID:306564" /db_xref="RGD:1306242" exon 1..616 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" misc_feature 94..96 /gene="Htra4" /gene_synonym="RGD1306242" /note="upstream in-frame stop codon" CDS 118..1584 /gene="Htra4" /gene_synonym="RGD1306242" /note="probable serine protease HTRA4; high-temperature requirement factor A4; serine protease HTR4" /codon_start=1 /product="serine protease HTR4 precursor" /protein_id="NP_001100791.1" /db_xref="GeneID:306564" /db_xref="RGD:1306242" /translation="MSRSKMSSQRLWAVRAQFLLLWLLLWAAPVPWAEARRSRVSLPC PDACDPTRCPPLPSCSAGSALVPDRCGCCQVCAAVEGQECGGARGRPCVPGLRCGAPF SREPSGRAWLGTCGCAEGAEGAAVCGSDGRTYPSLCALRKENRAARQRGALPAVPVQK GACGDSGTTRAGRLRTKYNFIAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIV SEDGLIVTNAHVLTNQQKIQVELQNGAQYEATVKDIDHKLDLALIKIEPDTDLPVLLL GRSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGKELGLKDSDIDYIQTDAIINH GNSGGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQFLADYHERQLKGKAPLQKKYL GLRMLPLTLNLLQEMKRQDPDFPDVSSGVFVYEVIQGSAAASSGLRDHDVIVSINGQP VTTTTDVIEAVKDNAFLSIIVLRGSQTLFLTVTPEIIN" sig_peptide 118..222 /gene="Htra4" /gene_synonym="RGD1306242" /inference="COORDINATES: ab initio prediction:SignalP:6.0" mat_peptide 223..1581 /gene="Htra4" /gene_synonym="RGD1306242" /product="Serine protease HTR4. /id=PRO_0000417601" /note="propagated from UniProtKB/Swiss-Prot (D3ZKF5.1)" misc_feature 754..1236 /gene="Htra4" /gene_synonym="RGD1306242" /note="propagated from UniProtKB/Swiss-Prot (D3ZKF5.1); Region: Serine protease. /evidence=ECO:0000250" exon 617..716 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 717..921 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 922..1116 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 1117..1149 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 1150..1264 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 1265..1322 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 1323..1418 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" exon 1419..2256 /gene="Htra4" /gene_synonym="RGD1306242" /inference="alignment:Splign:2.1.0" ORIGIN 1 tctgtccttt ataaagtctg gaggccggca gaggcagcat ccaggccagg aaaagaacgt 61 gttgctcatt tcggcccagt tgtgagccca gagtgaactg gaaaagtaga atcaacgatg 121 tcaaggagca agatgagctc ccagcggttg tgggctgtgc gagcacagtt tctcttgctg 181 tggctgctgc tctgggccgc gcctgttccg tgggctgagg ccaggaggtc tagagtctcc 241 ttgccctgcc cggacgcctg cgatcccacg cgctgcccgc ctctgcctag ctgctcggcc 301 ggctcggcgc tagtgccaga tcgctgcggc tgctgccaag tgtgcgccgc ggtcgagggc 361 caggagtgtg gcggggcgcg gggccggccg tgcgtcccgg ggctgcgctg cggcgccccg 421 ttctcccggg agccctcagg gcgcgcgtgg ctgggcacct gcggttgcgc ggagggtgca 481 gagggcgcgg cggtgtgcgg cagcgacggg cgcacttacc ccagcctgtg cgcgctccgc 541 aaggagaacc gagcggctcg ccagcggggt gcgctcccgg ctgtgccagt gcagaaaggt 601 gcctgcggcg actcagggac cacaagagca gggcggctcc ggacaaagta caacttcatc 661 gctgccgtgg tggagaaggt ggcaccgtct gtggttcact tgcagctgtt ccgcagatca 721 cctctcacca accaggaaat cccttcatcc agcggttccg ggttcatagt gtctgaggat 781 ggcctcattg tcaccaatgc ccatgtcctc accaaccagc agaagatcca ggtagagctc 841 cagaacgggg ctcagtatga agccactgtc aaagacatcg accataaact ggaccttgca 901 ctgattaaga tcgagccaga tactgacctt ccagtactgt tgctgggaag atcctctgac 961 ctccgggccg gagagtttgt ggtggctttg ggtagcccat tttccctgca gaacactgtg 1021 actgccggga ttgtcagcac cacacagaga ggcggcaaag agttgggact gaaggactca 1081 gacatagact atatccagac ggacgccatc attaaccacg gaaattctgg gggtccactg 1141 gtgaacttgg atggcgatgt gatcggtata aacaccctga aggtgaccgc agggatctct 1201 tttgcaatcc cctcagatag gatcagacag ttcctggcag actatcatga gcgccagttg 1261 aaaggaaagg ctcccttgca gaagaaatac ctgggtctta gaatgttgcc cctcactctg 1321 aacctccttc aggaaatgaa gaggcaagat cccgatttcc ctgatgtgag ctctggagtt 1381 tttgtatatg aagtgattca aggatcggcc gctgcaagct cggggttgag agaccatgat 1441 gtaattgtca gcataaacgg gcagcctgtc acgaccacaa ccgatgtcat tgaagctgtt 1501 aaggacaatg cctttctctc catcattgtt cttcgaggaa gccaaacctt gtttctgaca 1561 gtcacacctg aaataatcaa ttaagcacct tactttgaga aactgcctag caaaaccagt 1621 tatattacct ggtttctatc gaagacgaac cagagatggc aggttcttct gggtatcaag 1681 aaaagtggat gctttaaatg tataagtaca tgtgtgtgtg atacacacac tcgtgcacat 1741 gtgtacacac gtgtatacac acacacacac acacacacac acacacacac acacacacat 1801 tctcatggat cctgagggat taagcatgct cttctactac aaaaactttc gtgactcaag 1861 tggccgcagc tatggtgatc agagaaaaag taaagacagt aagaatggga aaacaggaga 1921 ctcctaacta aatcttcaca gggtgcttta cttaccgtct atatagccac taactgatat 1981 gtcacacaca tgtacaaaca atctacctac tagatctgaa tctggagtaa agaggcaatc 2041 atgttttaaa taacacccct ctgtatgctg aatttcccgg ggtatatcca ctttgggcca 2101 gggtttgtgg atagaaaggt cgtcaactct aagatagatt acaactgatg acgtcagacc 2161 accacacagg aatatgacca ttttagcggt agaaactatc ctggacctct ggtgtttctg 2221 agaatgtctt ctattaaaac aattttttga accatt //
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