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Rattus norvegicus zinc finger protein 57 (Zfp57), mRNA

NCBI Reference Sequence: NM_213565.4

FASTA Graphics 

LOCUS       NM_213565               1849 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus zinc finger protein 57 (Zfp57), mRNA.
ACCESSION   NM_213565 XM_342079
VERSION     NM_213565.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1849)
  AUTHORS   Takahashi,N., Coluccio,A., Thorball,C.W., Planet,E., Shi,H.,
            Offner,S., Turelli,P., Imbeault,M., Ferguson-Smith,A.C. and
            Trono,D.
  TITLE     ZNF445 is a primary regulator of genomic imprinting
  JOURNAL   Genes Dev 33 (1-2), 49-54 (2019)
   PUBMED   30602440
REFERENCE   2  (bases 1 to 1849)
  AUTHORS   Buck-Koehntop,B.A. and Defossez,P.A.
  TITLE     On how mammalian transcription factors recognize methylated DNA
  JOURNAL   Epigenetics 8 (2), 131-137 (2013)
   PUBMED   23324617
  REMARK    Review article
REFERENCE   3  (bases 1 to 1849)
  AUTHORS   Gehrig,S.M., van der Poel,C., Sayer,T.A., Schertzer,J.D.,
            Henstridge,D.C., Church,J.E., Lamon,S., Russell,A.P., Davies,K.E.,
            Febbraio,M.A. and Lynch,G.S.
  TITLE     Hsp72 preserves muscle function and slows progression of severe
            muscular dystrophy
  JOURNAL   Nature 484 (7394), 394-398 (2012)
   PUBMED   22495301
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1849)
  AUTHORS   Li,X., Ito,M., Zhou,F., Youngson,N., Zuo,X., Leder,P. and
            Ferguson-Smith,A.C.
  TITLE     A maternal-zygotic effect gene, Zfp57, maintains both maternal and
            paternal imprints
  JOURNAL   Dev Cell 15 (4), 547-557 (2008)
   PUBMED   18854139
REFERENCE   5  (bases 1 to 1849)
  AUTHORS   Mackay,D.J., Callaway,J.L., Marks,S.M., White,H.E., Acerini,C.L.,
            Boonen,S.E., Dayanikli,P., Firth,H.V., Goodship,J.A., Haemers,A.P.,
            Hahnemann,J.M., Kordonouri,O., Masoud,A.F., Oestergaard,E.,
            Storr,J., Ellard,S., Hattersley,A.T., Robinson,D.O. and Temple,I.K.
  TITLE     Hypomethylation of multiple imprinted loci in individuals with
            transient neonatal diabetes is associated with mutations in ZFP57
  JOURNAL   Nat Genet 40 (8), 949-951 (2008)
   PUBMED   18622393
REFERENCE   6  (bases 1 to 1849)
  AUTHORS   Alonso,M.B., Zoidl,G., Taveggia,C., Bosse,F., Zoidl,C., Rahman,M.,
            Parmantier,E., Dean,C.H., Harris,B.S., Wrabetz,L., Muller,H.W.,
            Jessen,K.R. and Mirsky,R.
  TITLE     Identification and characterization of ZFP-57, a novel zinc finger
            transcription factor in the mammalian peripheral nervous system
  JOURNAL   J Biol Chem 279 (24), 25653-25664 (2004)
   PUBMED   15070898
REFERENCE   7  (bases 1 to 1849)
  AUTHORS   Okazaki,S., Tanase,S., Choudhury,B.K., Setoyama,K., Miura,R.,
            Ogawa,M. and Setoyama,C.
  TITLE     A novel nuclear protein with zinc fingers down-regulated during
            early mammalian cell differentiation
  JOURNAL   J Biol Chem 269 (9), 6900-6907 (1994)
   PUBMED   8120052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA511208.1 and BC127468.1.
            
            On Oct 17, 2009 this sequence version replaced NM_213565.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA511208.1, DY312591.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 CA511208.1         1-9
            10-182              CA511208.1         11-183
            183-1849            BC127468.1         1-1667
FEATURES             Location/Qualifiers
     source          1..1849
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1849
                     /gene="Zfp57"
                     /note="zinc finger protein 57"
                     /db_xref="GeneID:361783"
                     /db_xref="RGD:1302981"
     exon            1..146
                     /gene="Zfp57"
                     /inference="alignment:Splign:2.1.0"
     exon            147..175
                     /gene="Zfp57"
                     /inference="alignment:Splign:2.1.0"
     exon            176..282
                     /gene="Zfp57"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    208..210
                     /gene="Zfp57"
                     /note="upstream in-frame stop codon"
     CDS             265..1485
                     /gene="Zfp57"
                     /note="zfp-57"
                     /codon_start=1
                     /product="zinc finger protein 57"
                     /protein_id="NP_998730.2"
                     /db_xref="GeneID:361783"
                     /db_xref="RGD:1302981"
                     /translation="MAAKKQSKSAKALRTTVRYEDVAVSFTQEEWEYLTSTQKTLYQK
                     VMSETFKNLTFVESKKKPQEPNPNLKDKDDDKSSTCTGVFKGGPFFFCLTCGKCFKKN
                     TFLFNHQFPVRSRRLAVTKPQSRKALGHKPQHRGDRPFFCNLCGKTYRDASGLSRHRR
                     AHVGYRPRSCPECGKCFRDQSEVNRHLKVHQNKKPVAGSHVKVHQNKPVASNQKQKGR
                     VPPTTRESPAPALRHLKVIQGPVARAKARSSRASSLEVRSTSVTVARPREKVYCPYCR
                     ITFTMRTCLLNHLKIHFRRQPNQHFCCKESHSSNTLRMQKIYNCPVCDSSFRGKESLL
                     NHLCSRRPIRLSKCWEILGHLLGYLREPLGNIFKVRESRKRRRKRISSDSSETEGPSG
                     SDEVMEVDTDSDLS"
     misc_feature    433..495
                     /gene="Zfp57"
                     /note="propagated from UniProtKB/Swiss-Prot (A0JPK3.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    796..798
                     /gene="Zfp57"
                     /note="Crucial for 5-methylcytosine recognition.
                     /evidence=ECO:0000250; propagated from
                     UniProtKB/Swiss-Prot (A0JPK3.1); other site"
     misc_feature    844..942
                     /gene="Zfp57"
                     /note="propagated from UniProtKB/Swiss-Prot (A0JPK3.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1378..1482
                     /gene="Zfp57"
                     /note="propagated from UniProtKB/Swiss-Prot (A0JPK3.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            283..433
                     /gene="Zfp57"
                     /inference="alignment:Splign:2.1.0"
     exon            434..1840
                     /gene="Zfp57"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccccttcctg ggttcacgcc gctgccttct ggtctgggct ggaacgcgcc caaccctttg
       61 tggggctgtg gtctgaggca acggctcaga agacgagcac cggggacggc ggggctgccg
      121 agccccgagt agggctgtcg aacgcgggct tcctggacca gaaaagaaca atcagatttc
      181 tagaagtggg caccaacaaa tagtggctag aagcagtctg gagtagaagt caaacaccta
      241 ggaccagcct ggcattccca aacaatggca gctaagaaac agtctaagtc tgccaaggcg
      301 ttaaggacaa cagtcagata tgaggacgtg gcagtgtctt tcacccagga agaatgggaa
      361 tatctgactt ctacacagaa gaccctttac caaaaagtga tgtcagaaac cttcaagaac
      421 ctgacatttg tggaaagcaa gaagaaacct caagaaccta acccaaatct gaaagataag
      481 gatgatgata agtcctccac ttgcacaggg gtattcaaag gtggaccatt ctttttctgt
      541 ctcacctgtg gcaaatgttt caaaaagaac accttcctct ttaatcacca gtttcctgtg
      601 aggtcccgga ggctggcggt cacaaagccg caaagccgca aagccctcgg tcataagccc
      661 cagcatcgcg gagacaggcc tttcttttgc aatctctgtg gcaagactta tcgtgatgct
      721 tctggactga gccgtcaccg acgtgctcac gtaggttata ggccccgttc ctgccctgag
      781 tgtggaaagt gcttccggga tcagtctgag gtcaaccgcc acctgaaggt acaccaaaac
      841 aagaaaccag tggctggcag ccacgtgaaa gtacaccaaa acaagccagt ggctagcaac
      901 cagaagcaga agggtagggt tccacctaca acacgtgaat ccccagcgcc agccctcagg
      961 catctgaaag tgatccaggg accagtggcc agggctaagg cacggagcag cagagcttca
     1021 tccctggagg tcagatccac ctcagttaca gtggcccgcc caagagaaaa ggtctattgt
     1081 ccctattgcc ggatcacttt taccatgaga acctgtctct tgaaccacct caagatccac
     1141 ttccggcgtc aacccaacca gcacttctgt tgcaaagagt cccactcgtc caacacactc
     1201 aggatgcaaa agatctacaa ttgccccgtc tgcgacagct cctttagggg gaaggagagc
     1261 ctgctgaatc acttgtgctc ccgaagacca atcaggctca gtaaatgctg ggaaatcctg
     1321 ggtcatctgc ttggctatct tcgtgaaccc ttgggaaata tttttaaagt aagggaatcc
     1381 aggaagagaa gacggaaacg cataagcagt gatagttctg aaacagaagg cccgtctggg
     1441 agtgatgagg tgatggaggt tgacaccgac tctgacctct cctgagtttg aaccctgaga
     1501 cccctgtggc agaaggaaaa acctaattct tggcttcaca catgcccgtg cacgaccccc
     1561 tctccccacc tcacagcata aatacaattt ttaaaactaa aagaagtgag ggtggggtct
     1621 aactgaggtc ttgtatttgg tttttcctga agatcgacct ctggcatcag gaggcttgag
     1681 caaggagaag agtggatgat gaaggaaaga gacaaggaaa gaaagagaag tgtgcacaaa
     1741 gaaacttgta ttattattaa ttagcaccta gcttgtttgt gtctgataca ccaccaagta
     1801 gtaattgttg aaaaaacgaa gaagaaaaaa aaaaaaaaaa aaaaaaaaa
//
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