LOCUS NM_213565 1849 bp mRNA linear ROD 03-APR-2024
DEFINITION Rattus norvegicus zinc finger protein 57 (Zfp57), mRNA.
ACCESSION NM_213565 XM_342079
VERSION NM_213565.4
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 1849)
AUTHORS Takahashi,N., Coluccio,A., Thorball,C.W., Planet,E., Shi,H.,
Offner,S., Turelli,P., Imbeault,M., Ferguson-Smith,A.C. and
Trono,D.
TITLE ZNF445 is a primary regulator of genomic imprinting
JOURNAL Genes Dev 33 (1-2), 49-54 (2019)
PUBMED 30602440
REFERENCE 2 (bases 1 to 1849)
AUTHORS Buck-Koehntop,B.A. and Defossez,P.A.
TITLE On how mammalian transcription factors recognize methylated DNA
JOURNAL Epigenetics 8 (2), 131-137 (2013)
PUBMED 23324617
REMARK Review article
REFERENCE 3 (bases 1 to 1849)
AUTHORS Gehrig,S.M., van der Poel,C., Sayer,T.A., Schertzer,J.D.,
Henstridge,D.C., Church,J.E., Lamon,S., Russell,A.P., Davies,K.E.,
Febbraio,M.A. and Lynch,G.S.
TITLE Hsp72 preserves muscle function and slows progression of severe
muscular dystrophy
JOURNAL Nature 484 (7394), 394-398 (2012)
PUBMED 22495301
REMARK Publication Status: Online-Only
REFERENCE 4 (bases 1 to 1849)
AUTHORS Li,X., Ito,M., Zhou,F., Youngson,N., Zuo,X., Leder,P. and
Ferguson-Smith,A.C.
TITLE A maternal-zygotic effect gene, Zfp57, maintains both maternal and
paternal imprints
JOURNAL Dev Cell 15 (4), 547-557 (2008)
PUBMED 18854139
REFERENCE 5 (bases 1 to 1849)
AUTHORS Mackay,D.J., Callaway,J.L., Marks,S.M., White,H.E., Acerini,C.L.,
Boonen,S.E., Dayanikli,P., Firth,H.V., Goodship,J.A., Haemers,A.P.,
Hahnemann,J.M., Kordonouri,O., Masoud,A.F., Oestergaard,E.,
Storr,J., Ellard,S., Hattersley,A.T., Robinson,D.O. and Temple,I.K.
TITLE Hypomethylation of multiple imprinted loci in individuals with
transient neonatal diabetes is associated with mutations in ZFP57
JOURNAL Nat Genet 40 (8), 949-951 (2008)
PUBMED 18622393
REFERENCE 6 (bases 1 to 1849)
AUTHORS Alonso,M.B., Zoidl,G., Taveggia,C., Bosse,F., Zoidl,C., Rahman,M.,
Parmantier,E., Dean,C.H., Harris,B.S., Wrabetz,L., Muller,H.W.,
Jessen,K.R. and Mirsky,R.
TITLE Identification and characterization of ZFP-57, a novel zinc finger
transcription factor in the mammalian peripheral nervous system
JOURNAL J Biol Chem 279 (24), 25653-25664 (2004)
PUBMED 15070898
REFERENCE 7 (bases 1 to 1849)
AUTHORS Okazaki,S., Tanase,S., Choudhury,B.K., Setoyama,K., Miura,R.,
Ogawa,M. and Setoyama,C.
TITLE A novel nuclear protein with zinc fingers down-regulated during
early mammalian cell differentiation
JOURNAL J Biol Chem 269 (9), 6900-6907 (1994)
PUBMED 8120052
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CA511208.1 and BC127468.1.
On Oct 17, 2009 this sequence version replaced NM_213565.3.
##Evidence-Data-START##
Transcript exon combination :: CA511208.1, DY312591.1 [ECO:0000332]
RNAseq introns :: mixed sample support SAMD00132261,
SAMD00132262 [ECO:0006172]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on conservation, expression,
longest protein
##RefSeq-Attributes-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-9 CA511208.1 1-9
10-182 CA511208.1 11-183
183-1849 BC127468.1 1-1667
FEATURES Location/Qualifiers
source 1..1849
/organism="Rattus norvegicus"
/mol_type="mRNA"
/strain="Sprague-Dawley"
/db_xref="taxon:10116"
/chromosome="20"
/map="20p12"
gene 1..1849
/gene="Zfp57"
/note="zinc finger protein 57"
/db_xref="GeneID:361783"
/db_xref="RGD:1302981"
exon 1..146
/gene="Zfp57"
/inference="alignment:Splign:2.1.0"
exon 147..175
/gene="Zfp57"
/inference="alignment:Splign:2.1.0"
exon 176..282
/gene="Zfp57"
/inference="alignment:Splign:2.1.0"
misc_feature 208..210
/gene="Zfp57"
/note="upstream in-frame stop codon"
CDS 265..1485
/gene="Zfp57"
/note="zfp-57"
/codon_start=1
/product="zinc finger protein 57"
/protein_id="NP_998730.2"
/db_xref="GeneID:361783"
/db_xref="RGD:1302981"
/translation="MAAKKQSKSAKALRTTVRYEDVAVSFTQEEWEYLTSTQKTLYQK
VMSETFKNLTFVESKKKPQEPNPNLKDKDDDKSSTCTGVFKGGPFFFCLTCGKCFKKN
TFLFNHQFPVRSRRLAVTKPQSRKALGHKPQHRGDRPFFCNLCGKTYRDASGLSRHRR
AHVGYRPRSCPECGKCFRDQSEVNRHLKVHQNKKPVAGSHVKVHQNKPVASNQKQKGR
VPPTTRESPAPALRHLKVIQGPVARAKARSSRASSLEVRSTSVTVARPREKVYCPYCR
ITFTMRTCLLNHLKIHFRRQPNQHFCCKESHSSNTLRMQKIYNCPVCDSSFRGKESLL
NHLCSRRPIRLSKCWEILGHLLGYLREPLGNIFKVRESRKRRRKRISSDSSETEGPSG
SDEVMEVDTDSDLS"
misc_feature 433..495
/gene="Zfp57"
/note="propagated from UniProtKB/Swiss-Prot (A0JPK3.1);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 796..798
/gene="Zfp57"
/note="Crucial for 5-methylcytosine recognition.
/evidence=ECO:0000250; propagated from
UniProtKB/Swiss-Prot (A0JPK3.1); other site"
misc_feature 844..942
/gene="Zfp57"
/note="propagated from UniProtKB/Swiss-Prot (A0JPK3.1);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1378..1482
/gene="Zfp57"
/note="propagated from UniProtKB/Swiss-Prot (A0JPK3.1);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
exon 283..433
/gene="Zfp57"
/inference="alignment:Splign:2.1.0"
exon 434..1840
/gene="Zfp57"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 ccccttcctg ggttcacgcc gctgccttct ggtctgggct ggaacgcgcc caaccctttg
61 tggggctgtg gtctgaggca acggctcaga agacgagcac cggggacggc ggggctgccg
121 agccccgagt agggctgtcg aacgcgggct tcctggacca gaaaagaaca atcagatttc
181 tagaagtggg caccaacaaa tagtggctag aagcagtctg gagtagaagt caaacaccta
241 ggaccagcct ggcattccca aacaatggca gctaagaaac agtctaagtc tgccaaggcg
301 ttaaggacaa cagtcagata tgaggacgtg gcagtgtctt tcacccagga agaatgggaa
361 tatctgactt ctacacagaa gaccctttac caaaaagtga tgtcagaaac cttcaagaac
421 ctgacatttg tggaaagcaa gaagaaacct caagaaccta acccaaatct gaaagataag
481 gatgatgata agtcctccac ttgcacaggg gtattcaaag gtggaccatt ctttttctgt
541 ctcacctgtg gcaaatgttt caaaaagaac accttcctct ttaatcacca gtttcctgtg
601 aggtcccgga ggctggcggt cacaaagccg caaagccgca aagccctcgg tcataagccc
661 cagcatcgcg gagacaggcc tttcttttgc aatctctgtg gcaagactta tcgtgatgct
721 tctggactga gccgtcaccg acgtgctcac gtaggttata ggccccgttc ctgccctgag
781 tgtggaaagt gcttccggga tcagtctgag gtcaaccgcc acctgaaggt acaccaaaac
841 aagaaaccag tggctggcag ccacgtgaaa gtacaccaaa acaagccagt ggctagcaac
901 cagaagcaga agggtagggt tccacctaca acacgtgaat ccccagcgcc agccctcagg
961 catctgaaag tgatccaggg accagtggcc agggctaagg cacggagcag cagagcttca
1021 tccctggagg tcagatccac ctcagttaca gtggcccgcc caagagaaaa ggtctattgt
1081 ccctattgcc ggatcacttt taccatgaga acctgtctct tgaaccacct caagatccac
1141 ttccggcgtc aacccaacca gcacttctgt tgcaaagagt cccactcgtc caacacactc
1201 aggatgcaaa agatctacaa ttgccccgtc tgcgacagct cctttagggg gaaggagagc
1261 ctgctgaatc acttgtgctc ccgaagacca atcaggctca gtaaatgctg ggaaatcctg
1321 ggtcatctgc ttggctatct tcgtgaaccc ttgggaaata tttttaaagt aagggaatcc
1381 aggaagagaa gacggaaacg cataagcagt gatagttctg aaacagaagg cccgtctggg
1441 agtgatgagg tgatggaggt tgacaccgac tctgacctct cctgagtttg aaccctgaga
1501 cccctgtggc agaaggaaaa acctaattct tggcttcaca catgcccgtg cacgaccccc
1561 tctccccacc tcacagcata aatacaattt ttaaaactaa aagaagtgag ggtggggtct
1621 aactgaggtc ttgtatttgg tttttcctga agatcgacct ctggcatcag gaggcttgag
1681 caaggagaag agtggatgat gaaggaaaga gacaaggaaa gaaagagaag tgtgcacaaa
1741 gaaacttgta ttattattaa ttagcaccta gcttgtttgt gtctgataca ccaccaagta
1801 gtaattgttg aaaaaacgaa gaagaaaaaa aaaaaaaaaa aaaaaaaaa
//