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Rat mRNA for membrane-associated intestinal alkaline phosphatase

GenBank: X17611.1

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LOCUS       X17611                  2225 bp    mRNA    linear   ROD 18-APR-2005
DEFINITION  Rat mRNA for membrane-associated intestinal alkaline phosphatase.
ACCESSION   X17611 S51096
VERSION     X17611.1
KEYWORDS    alkaline phosphatase; membrane-associated protein; phosphatase.
SOURCE      Rattus sp.
  ORGANISM  Rattus sp.
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Lowe,M., Strauss,A.W., Alpers,R., Seetharam,S. and Alpers,D.H.
  TITLE     Molecular cloning and expression of a cDNA encoding the
            membrane-associated rat intestinal alkaline phosphatase
  JOURNAL   Biochim. Biophys. Acta 1037 (2), 170-177 (1990)
   PUBMED   2155025
REFERENCE   2
  AUTHORS   Engle,M.J. and Alpers,D.H.
  TITLE     The two mRNAs encoding rat intestinal alkaline phosphatase
            represent two distinct nucleotide sequences
  JOURNAL   Clin. Chem. 38 (12), 2506-2509 (1992)
   PUBMED   1458592
REFERENCE   3  (bases 1 to 2225)
  AUTHORS   Lowe,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-1989) Lowe E., Washington University School of
            Medicine, Box 8231, St Louis MO 63103, U S A
COMMENT     On May 13, 2005 this sequence version replaced S51096.1.
            Data kindly reviewed (17-APR-1990) by Lowe M.E.
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Rattus sp."
                     /mol_type="mRNA"
                     /db_xref="taxon:10118"
                     /tissue_type="duodenum"
                     /clone_lib="lambda gt11"
                     /dev_stage="adult"
     CDS             45..1667
                     /codon_start=1
                     /product="precursor polypeptide (AA -20 to 520)"
                     /protein_id="CAA35613.1"
                     /db_xref="GOA:P15693"
                     /db_xref="InterPro:IPR001952"
                     /db_xref="InterPro:IPR017849"
                     /db_xref="InterPro:IPR017850"
                     /db_xref="InterPro:IPR018299"
                     /db_xref="UniProtKB/Swiss-Prot:P15693"
                     /translation="MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAK
                     KLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKT
                     YNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAG
                     KSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDV
                     ILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQA
                     SQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGR
                     IDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGT
                     SIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSE
                     THGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTP
                     VQNSAITMNNVLLSLQLLVSMLLLVGTALVVS"
     sig_peptide     45..104
                     /note="signal peptide (AA -20 to -1)"
     mat_peptide     105..1664
                     /product="alkaline phosphatase (AA 1 to 520)"
     misc_feature    2205..2211
                     /note="polyA signal"
     polyA_site      2225
                     /note="polyA site"
ORIGIN      
        1 cgataccttg ttccccagct gggcgtccat caatagcccc aaccatgcag ggagactggg
       61 tgctgctgct gcttttgggt ctcaggatac atctgtcctt tggtgtcatc ccagtggagg
      121 aggagaaccc agtcttctgg aatcaaaagg cgaaggaggc cctggatgtt gccaaaaagc
      181 tgcagcccat tcagacatcg gccaagaacc tcatcctctt cctgggagat gggatggggg
      241 tgcccacagt gacagccacc aggatactaa agggacaact gggtggtcat ctaggacctg
      301 agacacccct ggccatggac cacttcccat tcacggctct gtccaagaca tacaacgtgg
      361 acagacaggt cccagacagt gcaggcacag ccaccgccta tctctgtggg gtcaaagcca
      421 actacaagac catcggtgtg agcgcggctg ctcgattcaa ccagtgcaac agcacatttg
      481 gcaacgaggt cttctcagtg atgcaccgtg caaagaaagc agggaagtct gtgggcgtgg
      541 tgaccacgac cagagtgcag catgcctctc cagccggcac ctacgcgcac acggttaacc
      601 gagactggta ctcggatgca gacatgcctt cctccgccct gcaggagggc tgcaaggaca
      661 tcgccacaca gctcatttcc aacatggaca ttgatgtgat ccttggtgga ggccgaaagt
      721 tcatgtttcc caaggggaca ccagaccctg aatacccagg tgactctgac cagtctggag
      781 tcaggctgga tagtcggaac ttggtggagg agtggctggc aaaataccag gggacccggt
      841 atgtttggaa tcgagagcag ctcatgcagg cctctcagga cccagcagtg actcgcctca
      901 tgggcctctt tgagccaaca gaaatgaaat atgatgtcaa ccgaaacgcc tcagcagacc
      961 cctccctggc agagatgaca gaggtggccg tgcgcctgct gagcaggaat ccacaaggct
     1021 tctacctctt tgtagaagga ggtcgtattg accaaggcca ccatgcgggc acggcttacc
     1081 tggcactgac tgaggctgtc atgttcgact ccgccatcga aaaggccagc cagcttacca
     1141 atgagaagga cacgctaacg ctcatcactg cggaccactc ccatgtcttt gcttttggtg
     1201 gctatacact tagggggacc tccatctttg gtctggcccc actcaatgcc caggatggca
     1261 aatcctacac ctccattctc tatggcaacg gcccaggtta tgtgcttaat tcaggcaacc
     1321 ggcccaatgt cactgatgcc gagagtggtg atgtcaacta caagcagcag gcagcagtac
     1381 ccctgtcgtc agagacccac ggtggggagg acgtggccat attcgcgcgt ggcccacagg
     1441 cgcacctggt gcacggagtg caggaacaga actacatcgc gcacgtcatg gccttcgcag
     1501 gctgcctgga gccctacacc gactgcggtc tggcgccccc tgcagacgag aacagaccaa
     1561 ccaccccggt ccagaacagt gccatcacta tgaacaatgt ccttctgtcc ctgcagctcc
     1621 tggtcagcat gctgctgcta gtcgggacag ccttggtggt gtcctgatgg tcaggtcccc
     1681 cactgggctc ctccctctgc tggttgctcc ccacgacccc ccatagattc ctgtgccctg
     1741 tcagtcctga gttcatcatt ctctacccaa gggtctcaac gctggccttt gcaccccaac
     1801 ttggttgttc tcttatccag atgctgaaac attatcccgg cccacagttc taagggccac
     1861 ctctgggaat atactctgag atttgcttta taactctggg cttccgcttc tcaactgcag
     1921 tgggaggtac cgaacggtat ccagaaagct acagtttgtg gctgtcccag actccccttc
     1981 aatccatcac ccttcacagg gaccaagtaa ctcacatttt caggccttag cttgttccta
     2041 tgaaaggaaa tctcaaaagt ccaggagact gtgggttctc aagcaagcag cgcagagcag
     2101 ccttgggccc ccacccctgg tccatctcag gctgcatata gaaaccggac aaagaatatt
     2161 accgactctt gtccccagtc cttgaagaga cacaatgaca acaaaattaa atgcttatat
     2221 aaggt
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the Alpi gene (NM_022665.3).

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