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Binding affinity towards nicotinic acetylcholine receptor (nAChR) using [3H]cytisine as radioligand in rat brain
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -4 M was reported; response was dose related
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -5 M was reported
Assay data:2 Tested
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -6 M was reported
Assay data:6 Tested
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -7 M was reported
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -12- 10 E -5 M was reported
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -8 - 10 E -4 M was reported
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 2.5*10e-9-7.5*10e-5 M was reported
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 2.5*10e-9-2.5*10e-5 M was reported
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -4 M was reported; response was dose related
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -9 - 10 E -6 M was reported
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a particular dose range 5E-9 - 1.5E-8 was reported
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -4 M was reported
Assay data:9 Tested
Binding affinity towards nicotinic acetylcholine receptor (nAChR)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Evaluated for its binding affinity towards Nicotinic acetylcholine receptor in rat brain homogenate
Assay data:13 Active, 6 Activity ≤ 1 µM, 18 Tested
Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)
Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested
Compound was evaluated for functional potency and efficacy at rat Nicotinic acetylcholine receptor in PC12 cells (ganglionic)
Compound was evaluated for functional potency and efficacy at rat Nicotinic acetylcholine receptor subtype DA release
Compound was evaluated for potency and efficacy at rat Nicotinic acetylcholine receptor subtype DA release;
Binding affinity towards neuronal nicotinic receptor using [3H]cytisine as radioligand in rat forebrain homogenates
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