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Rat MC3 receptor (Melanocortin receptors)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at rat MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at rat MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity at rat MC3R
Concentration of compound at 50% maximum cAMP accumulation at rat melanocortin-3 receptor
Functional activity as concentration at 50% maximum cAMP accumulation in rat Melanocortin-3 receptor (rMC3R)
Effective concentration for maximum agonist response towards rat melanocortin 3 receptor (MC3R); No activity up to 10e-5 M
Maximal agonist response at rat melanocortin 3 receptor (MC3R)
Assay data:12 Active, 4 Activity ≤ 1 nM, 12 Activity ≤ 1 µM, 13 Tested
Percentage of cAMP accumulation at 10 uM relative to alpha-MSH at rat Melanocortin-3 receptor
Evaluated for binding affinity against rat Melanocortin-3 receptor (rMC3R) by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cells
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