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Agonist activity at rat FFA3 receptor
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY11 co-expressing chimeric Gpa1/Galpha12 at 0.5 mM to 50 mM incubated for 48 hrs by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY11 co-expressing chimeric Gpa1/Galpha13 at 0.5 mM to 50 mM incubated for 48 hrs by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay
Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY11 co-expressing chimeric Gpa1/Ga0 at 0.5 mM to 50 mM incubated for 48 hrs by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay
Agonist activity at GPR41 in rat primary adipocytes assessed as inhibition of isoprenaline-induced cAMP accumulation at 0.01 M to 0.1 M incubated for 10 mins at 37 degC by ELISA
Agonist activity at rat GPR41 expressed in HEK293T cell membranes co-expressing Go1alpha protein assessed as stimulation of [35S]GTPgammaS binding at 0.1 microM to 0.1 M incubated for 30 mins by scintillation counting method
Assay data:3 Active, 3 Tested
Agonist activity at GPR41 in rat primary adipocytes assessed as inhibition of isoprenaline-induced lipolysis by measuring glycerol level after 2 hrs
Assay data:1 Active, 4 Tested
Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay
Assay data:8 Active, 57 Tested
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