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Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cells
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of rat brain farnesyltransferase in 5 mM potassium phosphate and 50 mM HEPES buffer
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Inhibition of rat brain farnesyltransferase in 50 mM HEPES buffer
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
Inhibition of rat brain farnesyltransferase in 30 mM potassium phosphate buffer
Inhibitory concentration against rat brain farnesyltransferase
Assay data:37 Active, 25 Activity ≤ 1 µM, 42 Tested
Inhibition of Farnesyltransferase from rat brain
Assay data:10 Active, 9 Activity ≤ 1 µM, 11 Tested
Inhibition of Farnesyltransferase in competitive manner with respect to FPP (farnesyl diphosphate) at 0.6 uM FPP and 3.6 uM Ras peptide.
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Farnesyltransferase in competitive manner with respect to FPP (farnesyl diphosphate) at 0.6 uM FPP and 0.36 uM Ras peptide
Inhibition of Farnesyltransferase in cells, evaluated in a radiotracer assay for farnesyltransferase inhibition (CRAFTI), in cultured H-ras-transformed Rat cells
Assay data:25 Active, 14 Activity ≤ 1 nM, 25 Activity ≤ 1 µM, 25 Tested
Inhibition of Farnesyltransferase in H-ras-transformed Rat cells by radiotracer assay (CRAFTI)
Inhibition of Farnesyltransferase
Assay data:5 Active, 5 Activity ≤ 1 µM, 9 Tested
Inhibition of FTase in competitive manner with respect to FPP (farnesyl diphosphate) at 6.0 uM FPP and 0.36 uM Ras peptide.
In vitro inhibitory activity against Farnesyltransferase (FTase)
Assay data:27 Active, 18 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 27 Tested
In vitro inhibition of Farnesyltransferase (FT) by using FT [3H]-SPA kit.
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
In vitro inhibition of rat farnesyltransferase.
Assay data:18 Active, 17 Activity ≤ 1 µM, 18 Tested
Activity against rat brain Farnesyltransferase
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Activity against rat Farnesyltransferase
Assay data:4 Active, 3 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
In vitro ability to displace radiolabeled FTI from farnesyltransferase in cultured Ha-ras transformed RAT1 cells
Assay data:23 Active, 23 Activity ≤ 1 µM, 24 Tested
Tested for inhibitory activity against rat brain p21ras Ras Farnesyltransferase (FTase)
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
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