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Activation of rat CAR expressed in rat hepatocytes coexpressing CYP2B1 at 100 uM after 24 hrs by dual luciferase reporter gene assay relative to phenobarbital
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of rat CAR expressed in rat hepatocytes coexpressing CYP2B1 at 60 uM after 24 hrs by dual luciferase reporter gene assay relative to phenobarbital
Activation of rat CAR expressed in rat hepatocytes coexpressing CYP2B1 at 30 uM after 24 hrs by dual luciferase reporter gene assay relative to phenobarbital
Activation of rat CAR expressed in rat hepatocytes coexpressing CYP2B1 at 0.1 to 10 uM after 24 hrs by dual luciferase reporter gene assay
Activation of rat CAR expressed in rat hepatocytes coexpressing CYP2B1 at 1 uM after 24 hrs by dual luciferase reporter gene assay
Activation of rat CAR expressed in rat hepatocytes coexpressing CYP2B1 at 100 uM after 24 hrs by dual luciferase reporter gene assay relative to control
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of CAR in rat hepatocytes assessed as increase in CYP2B-mediated benzyloxyresorufin O-dealkylation at 100 uM after 24 hrs by spectrofluorometric analysis relative to control
Activation of CAR in rat hepatocytes assessed as increase in CYP2B-mediated benzyloxyresorufin O-dealkylation at 30 uM after 24 hrs by spectrofluorometric analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as increase in CYP2B-mediated benzyloxyresorufin O-dealkylation at 10 uM after 24 hrs by spectrofluorometric analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as increase in CYP2B-mediated benzyloxyresorufin O-dealkylation at 3 uM after 24 hrs by spectrofluorometric analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as increase in CYP2B-mediated benzyloxyresorufin O-dealkylation at 1 uM after 24 hrs by spectrofluorometric analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as upregulation of CYP2B1 mRNA expression at 100 uM after 24 hrs by RT-PCR analysis relative to control
Activation of CAR in rat hepatocytes assessed as upregulation of CYP2B1 mRNA expression at 30 uM after 24 hrs by RT-PCR analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as upregulation of CYP2B1 mRNA expression at 10 uM after 24 hrs by RT-PCR analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as upregulation of CYP2B1 mRNA expression at 3 uM after 24 hrs by RT-PCR analysis relative to phenobarbital
Activation of CAR in rat hepatocytes assessed as effect on CYP2B1 mRNA expression at 1 uM after 24 hrs by RT-PCR analysis
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