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Induction of CYP2B6 activity in human HepaRG cells at 5 to 10 uM incubated for 96 hrs by liquid chromatography with tandem mass spectrometry-based substrate cocktail assay
Assay data:1 Tested
SummaryRelated BioAssays by Target
Induction of CYP2B6 activity in human HepaRG cells at 10 uM incubated for 96 hrs by liquid chromatography with tandem mass spectrometry-based substrate cocktail assay
Induction of CYP2B6 activity in human HepaRG cells at 0.5 uM incubated for 96 hrs by liquid chromatography with tandem mass spectrometry-based substrate cocktail assay
Inhibition of CYP2B6 (unknown origin)
Assay data:2 Tested
Inhibition of CYP2B6 in human liver microsomes upto 30 uM
Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate in presence of NADPH by LC-MS/MS analysis
Inhibition of CYP2B6 in human liver microsomes in presence of NADPH incubated for 15 mins by LC-MS analysis
Inhibition of CYP450 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of CYP450 in human liver microsomes
Assay data:1 Active, 2 Tested
Reversible inhibition of CYP2B6 in human liver microsomes in presence of NADPH by LC-MS/MS analysis
Time/NADPH-dependent inhibition of CYP2B6 in human liver microsomes
Reversible inhibition of CYP2B6 in human liver microsomes
Assay data:1 Active, 1 Tested
Inhibition of CYP2B6 in human liver microsomes preincubated for 5 mins in presence of substrate followed by NADPH addition and measured after 10 mins by LC/MS analysis
Assay data:1 Active, 7 Tested
Inhibition of CYP2B6 in human liver microsomes using amfebutamone HCL as substrate pretreated for 5 mins followed by substrate addition and measured after 10 mins in presence of NADPH by LC-MS/MS analysis
Inhibition of CYP2B6 in human liver microsomes using Bupropion as substrate incubated for 30 mins in presence of NADPH by LC-MS/MS analysis
Induction of CYP2B6 (unknown origin)
Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate incubated for 10 mins in presence of NADPH by LC-MS analysis
Inhibition of CYP2B6 in human liver microsomes preincubated for 5 mins followed by NADPH addition by LC-MS/MS analysis
Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate by LC-MS/MS analysis
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