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HIV Enzyme Data
Assay data:46810 Tested
Summary
HIV Cellular Data
Assay data:126857 Tested
High-throughput screening primary assay to identify small molecule activators of human guanylyl cyclase B (GC-B) receptor activity
Assay data:399 Active, 370620 Tested
SummaryCompounds, Active
Inhibition of recombinant PKM2 (unknown origin) Gly128, Lys207, Hie78, Asn75, Ile51, Lys367, Gly79 residues
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assay
Assay data:5 Active, 5 Tested
Selectivity index, log ratio of Inhibition of CYP450 in human liver microsomes assessed as inhibition of EpETrE formation in presence of arachidonic acid to Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid
Assay data:31 Tested
SummaryPubMed Citation
Inhibition of CYP450 in human liver microsomes assessed as inhibition of EpETrE formation at 10 uM in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation at 10 uM in presence of arachidonic acid and NADPH by multi-enzyme assay based LC-MS/MS analysis relative to control
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
DPP III Enzyme Activity Assay from Article 10.1111/cbdd.12887: "Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach."
Assay data:15 Tested
Inhibition Assay from Article 10.1080/14756360109162353: "Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer."
Assay data:5 Active, 14 Tested
NCI human tumor cell line growth inhibition assay. Data for the KM12 Non-Small Cell Lung cell line, single concentration
Assay data:3444 Active, 76734 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Non-Small Cell Lung cell line, single concentration
Assay data:3073 Active, 74254 Tested
NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Non-Small Cell Lung cell line, single concentration
Assay data:5131 Active, 77082 Tested
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell Lung cell line, single concentration
Assay data:4318 Active, 77515 Tested
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Non-Small Cell Lung cell line, single concentration
Assay data:3653 Active, 76840 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Non-Small Cell Lung cell line, single concentration
Assay data:5608 Active, 76570 Tested
NCI human tumor cell line growth inhibition assay. Data for the T-47D Non-Small Cell Lung cell line, single concentration
Assay data:3353 Active, 74196 Tested
NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Non-Small Cell Lung cell line, single concentration
Assay data:3002 Active, 76488 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Non-Small Cell Lung cell line, single concentration
Assay data:3404 Active, 76205 Tested
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