Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of human aromatase using ASD as substrate pre-incubated for 5 mins followed by substrate addition and measured after 16 hrs by UV/vis-spectrophotometry
Assay data:606 Active, 35 Activity ≤ 1 nM, 379 Activity ≤ 1 µM, 701 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant PKM2 (unknown origin) Ile335, Lys367, Lys207, Thr129, Lys206, Lys207, Asn75, Hie78 residues
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assay
Assay data:5 Active, 5 Tested
Inhibition of recombinant CYP19A1 (unknown origin) using dibenzylfluorescein as substrate incubated for 30 mins in presence of NADPH by fluorescence assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition Assay from Article 10.1080/14756360109162353: "Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer."
Assay data:5 Active, 14 Tested
Inhibition of human CYP1B1 expressed in Escherichia coli DH5alpha coexpressing human NADPH P450 reductase using 7-ethoxyresorufin as substrate in presence of NADP+ by spectrofluorometeric analysis
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate at 20 uM incubated for 15 mins by HPLC method
Assay data:25 Active, 25 Tested
Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubated for 15 mins by HPLC method
Assay data:3 Active, 6 Tested
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.
Assay data:9273 Active, 641570 Tested
Binding affinity to unilamellar vesicles of DPPC in D2O at 1:5 drug to lipid molar ratio at 323 K by [13C]-NMR spectroscopic analysis
Assay data:6 Active, 6 Tested
SummaryCompounds, ActivePubMed Citation
Binding affinity to unilamellar vesicles of DPPC in D2O at 1:5 drug to lipid molar ratio at 323 K by [1H]-NMR spectroscopic analysis
Luminescence-based cell-based high throughput confirmation assay to identify agonists of the DAF-12 from the parasite H. glycines (hgDAF-12).
Assay data:2664 Active, 3347 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the DAF-12 from the parasite H. glycines (hgDAF-12).
Assay data:6840 Active, 370276 Tested
Inhibition of transmembrane tumor-associated human carbonic anhydrase 12 preincubated for 12 hrs by stopped flow CO2 hydration assay
Assay data:4 Active, 4 Tested
Inhibition of transmembrane tumor-associated human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay
Assay data:7 Active, 7 Tested
Inhibition of transmembrane tumor-associated human carbonic anhydrase 9 preincubated for 12 hrs by stopped flow CO2 hydration assay
Inhibition of transmembrane tumor-associated human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assay
Inhibition of cytosolic human carbonic anhydrase 2 preincubated for 12 hrs by stopped flow CO2 hydration assay
Inhibition of cytosolic human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay
Assay data:21 Active, 1 Activity ≤ 1 µM, 24 Tested
Inhibition of cytosolic human carbonic anhydrase 1 preincubated for 12 hrs by stopped flow CO2 hydration assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on