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Cytochrome P450 Family 3 Subfamily A Member 4 (CYP3A4) small molecule antagonists: luciferase reporter qHTS assay
Assay data:1792 Active, 248 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily C Member 9 (CYP2C9) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2931 Active, 3 Activity ≤ 1 nM, 133 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) small molecule antagonists: luciferase reporter qHTS assay
Assay data:3508 Active, 4 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 9667 Tested
Human pregnane X receptor (PXR) small molecule agonists: Summary
Assay data:2076 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Progesterone receptor (PR) small molecule antagonists, qHTS assay: Summary
Assay data:1059 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Human pregnane X receptor (PXR) small molecule agonists, qHTS assay
Assay data:2218 Active, 1 Activity ≤ 1 nM, 106 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
CCRIS mutagenicity studies
Assay data:4929 Active, 8266 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library: Summary
Assay data:309 Active, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library: Summary
Assay data:390 Active, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway in the presence of an antagonist: Summary
Assay data:219 Active, 9667 Tested
qHTS assay to identify small molecule HDAC inhibitors: Summary
Assay data:421 Active, 16 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway in the presence of an antagonist
Assay data:257 Active, 66 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881: Summary
Assay data:1108 Active, 2 Activity ≤ 1 nM, 246 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881
Assay data:1453 Active, 4 Activity ≤ 1 nM, 292 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the thyroid stimulating hormone receptor (TSHR) signaling pathway: Summary
Assay data:415 Active, 34 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the constitutive androstane receptor (CAR) signaling pathway: Summary
Assay data:1090 Active, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library
Assay data:318 Active, 199 Activity ≤ 1 µM, 9667 Tested
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