PMC Links for Gene (Select 100362347) - PMC

Select item 33615841.

Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development

Heon Park, Karen Staehling, Mark Tsang, Mark W. Appleby, Mary E. Brunkow, Daciana Margineantu, David M. Hockenbery, Tania Habib, H. Denny Liggitt, George Carlson, Brian M. Iritani

Immunity. Author manuscript; available in PMC 2013 May 25.

Published in final edited form as: Immunity. 2012 May 25; 36(5): 769–781. Published online 2012 May 17. doi: 10.1016/j.immuni.2012.02.019

PMCID:: PMC3361584

Abstract Article PDF–4.5M

Select item 60809352.

GATOR1-dependent recruitment of FLCN–FNIP to lysosomes coordinates Rag GTPase heterodimer nucleotide status in response to amino acids

Jin Meng, Shawn M. Ferguson

J Cell Biol. 2018 Aug 6; 217(8): 2765–2776. doi: 10.1083/jcb.201712177

PMCID:: PMC6080935

Abstract Article PDF–2.6M

Select item 50673003.

Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot

Deborah C.I. Goberdhan, Clive Wilson, Adrian L. Harris

Cell Metab. 2016 Apr 12; 23(4): 580–589. doi: 10.1016/j.cmet.2016.03.013

PMCID:: PMC5067300

Abstract Article PDF–2.2M

Select item 34385384.

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

Ravi K. Nookala, Lars Langemeyer, Angela Pacitto, Bernardo Ochoa-Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazan, Tom L. Blundell

Open Biol. 2012 Aug; 2(8): 120071. doi: 10.1098/rsob.120071

PMCID:: PMC3438538

Abstract Article PDF–1.2M

Select item 43863365.

Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn

Hisashi Hasumi, Masaya Baba, Yukiko Hasumi, Martin Lang, Ying Huang, HyoungBin F. Oh, Masayuki Matsuo, Maria J. Merino, Masahiro Yao, Yusuke Ito, Mitsuko Furuya, Yasuhiro Iribe, Tatsuhiko Kodama, Eileen Southon, Lino Tessarollo, Kunio Nagashima, Diana C. Haines, W. Marston Linehan, Laura S. Schmidt

Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13): E1624–E1631. Published online 2015 Mar 16. doi: 10.1073/pnas.1419502112

PMCID:: PMC4386336

Abstract Article PDF–1.9M

Select item 34187206.

The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development

Masaya Baba, Jonathan R. Keller, Hong-Wei Sun, Wolfgang Resch, Stefan Kuchen, Hyung Chan Suh, Hisashi Hasumi, Yukiko Hasumi, Kyong-Rim Kieffer-Kwon, Carme Gallego Gonzalez, Robert M. Hughes, Mara E. Klein, Hyoungbin F. Oh, Paul Bible, Eileen Southon, Lino Tessarollo, Laura S. Schmidt, W. Marston Linehan, Rafael Casellas

Blood. 2012 Aug 9; 120(6): 1254–1261. Prepublished online 2012 Jun 18. doi: 10.1182/blood-2012-02-410407

PMCID:: PMC3418720

Abstract Article

Select item 63703197.

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90

Rebecca A. Sager, Mark R. Woodford, Sarah J. Backe, Alan M. Makedon, Alexander J. Baker-Williams, Bryanna T. DiGregorio, David R. Loiselle, Timothy A. Haystead, Natasha E. Zachara, Chrisostomos Prodromou, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour

Cell Rep. Author manuscript; available in PMC 2019 Feb 11.

Published in final edited form as: Cell Rep. 2019 Jan 29; 26(5): 1344–1356.e5. doi: 10.1016/j.celrep.2019.01.018

PMCID:: PMC6370319

Abstract Article PDF–2.3M

Select item 37873828.

Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases

Constance S. Petit, Agnes Roczniak-Ferguson, Shawn M. Ferguson

J Cell Biol. 2013 Sep 30; 202(7): 1107–1122. doi: 10.1083/jcb.201307084

PMCID:: PMC3787382

Abstract Article PDF–4.1M

Select item 30121179.

Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization

Seung-Beom Hong, HyoungBin Oh, Vladimir A. Valera, Masaya Baba, Laura S. Schmidt, W. Marston Linehan

PLoS One. 2010; 5(12): e15793. Published online 2010 Dec 29. doi: 10.1371/journal.pone.0015793

PMCID:: PMC3012117

Abstract Article PDF–3.7M

Select item 159246410.

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

Masaya Baba, Seung-Beom Hong, Nirmala Sharma, Michelle B. Warren, Michael L. Nickerson, Akihiro Iwamatsu, Dominic Esposito, William K. Gillette, Ralph F. Hopkins, III, James L. Hartley, Mutsuo Furihata, Shinya Oishi, Wei Zhen, Terrence R. Burke, Jr., W. Marston Linehan, Laura S. Schmidt, Berton Zbar

Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42): 15552–15557. Published online 2006 Oct 6. doi: 10.1073/pnas.0603781103

PMCID:: PMC1592464

Abstract Article PDF–1003K

Select item 419836011.

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation

Elaine A Dunlop, Sara Seifan, Tijs Claessens, Christian Behrends, Miriam AF Kamps, Ewelina Rozycka, Alain J Kemp, Ravi K Nookala, John Blenis, Barry J Coull, James T Murray, Maurice AM van Steensel, Simon Wilkinson, Andrew R Tee

Autophagy. 2014 Oct 1; 10(10): 1749–1760. Published online 2014 Jul 22. doi: 10.4161/auto.29640

PMCID:: PMC4198360

Abstract Article PDF–5.2M

Select item 493134412.

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

Mark R. Woodford, Diana M. Dunn, Adam R. Blanden, Dante Capriotti, David Loiselle, Chrisostomos Prodromou, Barry Panaretou, Philip F. Hughes, Aaron Smith, Wendi Ackerman, Timothy A. Haystead, Stewart N. Loh, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour

Nat Commun. 2016; 7: 12037. Published online 2016 Jun 29. doi: 10.1038/ncomms12037

PMCID:: PMC4931344

Abstract Article PDF–5.6M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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