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Select item 65630501.

Involvement of TREK-1 Channel in Cell Viability of H9c2 Rat Cardiomyoblasts Affected by Bupivacaine and Lipid Emulsion

Jun Ho Yang, Adrian S. Siregar, Eun-Jin Kim, Marie Merci Nyiramana, Eui-Jung Shin, Jaehee Han, Ju-Tae Sohn, Jong Woo Kim, Dawon Kang

Cells. 2019 May; 8(5): 454. Published online 2019 May 14. doi: 10.3390/cells8050454

PMCID:: PMC6563050

Abstract Article PDF–3.2M

Select item 64953932.

The Role of the Two‐Pore Domain Potassium Channel TREK‐1 in the Therapeutic Effects of Escitalopram in a Rat Model of Poststroke Depression

Dai‐Hua Lin, Xiang‐Rong Zhang, Dong‐Qing Ye, Guang‐Jun Xi, Jiao‐Jie Hui, Shan‐Shan Liu, Lin‐Jiang Li, Zhi‐Jun Zhang

CNS Neurosci Ther. 2015 Jun; 21(6): 504–512. Published online 2015 Feb 10. doi: 10.1111/cns.12384

PMCID:: PMC6495393

Abstract Article PDF–1.2M

Select item 58276303.

Increased Expression of TREK-1 K⁺ Channel in the Dorsal Root Ganglion of Rats with Detrusor Overactivity After Partial Bladder Outlet Obstruction

Junlong Zhang, Mingxin Cao, Yu Chen, Zi Wan, Hua Wang, Huanyi Lin, Weijie Liang, Yueyou Liang

Med Sci Monit. 2018; 24: 1064–1071. Published online 2018 Feb 20. doi: 10.12659/MSM.908792

PMCID:: PMC5827630

Abstract Article PDF–6.7M

Select item 42106674.

Systems approach to the study of stretch and arrhythmias in right ventricular failure induced in rats by monocrotaline

David Benoist, Rachel Stones, Alan P. Benson, Ewan D. Fowler, Mark J. Drinkhill, Matthew E.L. Hardy, David A. Saint, Olivier Cazorla, Olivier Bernus, Ed White

Prog Biophys Mol Biol. 2014 Aug; 115(2-3): 162–172. doi: 10.1016/j.pbiomolbio.2014.06.008

PMCID:: PMC4210667

Abstract Article

Select item 33836685.

Optical control of endogenous proteins with a photo-switchable conditional subunit reveals a role for TREK1 in GABAB signaling

Guillaume Sandoz, Joshua Levitz, Richard H. Kramer, Ehud Y. Isacoff

Neuron. Author manuscript; available in PMC 2013 Jun 21.

Published in final edited form as: Neuron. 2012 Jun 21; 74(6): 1005–1014. doi: 10.1016/j.neuron.2012.04.026

PMCID:: PMC3383668

Abstract Article PDF–1.4M

Select item 33348316.

Leak K⁺ channel mRNAs in dorsal root ganglia: Relation to inflammation and spontaneous pain behaviour

Barnaby Marsh, Cristian Acosta, Laiche Djouhri, Sally N. Lawson

Mol Cell Neurosci. 2012 Mar; 49-531(3): 375–386. doi: 10.1016/j.mcn.2012.01.002

PMCID:: PMC3334831

Abstract Article PDF–1020K

Select item 98438737.

Axonal membrane stretch suppresses neuronal excitability by activating mechanosensitive K2P channels at the node of Ranvier

Hirosato Kanda, Koichi Noguchi, Yi Dai

Mol Brain. 2023; 16: 8. Published online 2023 Jan 17. doi: 10.1186/s13041-023-01000-6

PMCID:: PMC9843873

Abstract Article PDF–1.0M

Select item 73653168.

Trek1 contributes to maintaining nasal epithelial barrier integrity

Jing Jiang, Jiang-Qi Liu, Jing Li, Meng Li, Hong-Bin Chen, Hao Yan, Li-Hua Mo, Shu-Qi Qiu, Zhi-Gang Liu, Ping-Chang Yang

Sci Rep. 2015; 5: 9191. Published online 2015 Mar 17. doi: 10.1038/srep09191

PMCID:: PMC7365316

Abstract Article PDF–924K

Select item 68954259.

TREK-1 and TRAAK are principal K⁺ channels at the nodes of Ranvier for rapid action potential conduction on mammalian myelinated afferent nerves

Hirosato Kanda, Jennifer Ling, Sotatsu Tonomura, Koichi Noguchi, Sadis Matalon, Jianguo G. Gu

Neuron. Author manuscript; available in PMC 2020 Dec 4.

Published in final edited form as: Neuron. 2019 Dec 4; 104(5): 960–971.e7. Published online 2019 Oct 17. doi: 10.1016/j.neuron.2019.08.042

PMCID:: PMC6895425

Abstract Article PDF–2.0M

Select item 406229710.

Activation of K₂P channel–TREK1 mediates the neuroprotection induced by sevoflurane preconditioning

L. Tong, M. Cai, Y. Huang, H. Zhang, B. Su, Z. Li, H. Dong

Br J Anaesth. 2014 Jul; 113(1): 157–167. Published online 2013 Oct 22. doi: 10.1093/bja/aet338

PMCID:: PMC4062297

Abstract Article PDF–843K

Select item 318148411.

The pore structure and gating mechanism of K2P channels

Paula L Piechotta, Markus Rapedius, Phillip J Stansfeld, Murali K Bollepalli, Gunter Erhlich, Isabelle Andres-Enguix, Hariolf Fritzenschaft, Niels Decher, Mark S P Sansom, Stephen J Tucker, Thomas Baukrowitz

EMBO J. 2011 Aug 31; 30(17): 3607–3619. Published online 2011 Aug 5. doi: 10.1038/emboj.2011.268

Correction in:: EMBO J. 2011 Nov 2; 30(21): 4515.

PMCID:: PMC3181484

Abstract Article PDF–1.4M

Select item 293796212.

Dominant Negative Effects of a Non-conducting TREK1 Splice Variant Expressed in Brain

Emma L. Veale, Kathryn A. Rees, Alistair Mathie, Stefan Trapp

J Biol Chem. 2010 Sep 17; 285(38): 29295–29304. Published online 2010 Jul 6. doi: 10.1074/jbc.M110.108423

PMCID:: PMC2937962

Abstract Article PDF–3.8M

Select item 252946613.

Alternative translation initiation in rat brain yields K_2P2.1 potassium channels permeable to sodium

Dierk Thomas, Leigh D. Plant, Christina M. Wilkens, Zoe A. McCrossan, Steve A. N. Goldstein

Neuron. Author manuscript; available in PMC 2009 Jun 26.

Published in final edited form as: Neuron. 2008 Jun 26; 58(6): 859–870. doi: 10.1016/j.neuron.2008.04.016

PMCID:: PMC2529466

Abstract Article PDF–1.3M

Select item 147816714.

TREK-1, a K⁺ channel involved in polymodal pain perception

Abdelkrim Alloui, Katharina Zimmermann, Julien Mamet, Fabrice Duprat, Jacques Noël, Jean Chemin, Nicolas Guy, Nicolas Blondeau, Nicolas Voilley, Catherine Rubat-Coudert, Marc Borsotto, Georges Romey, Catherine Heurteaux, Peter Reeh, Alain Eschalier, Michel Lazdunski

EMBO J. 2006 Jun 7; 25(11): 2368–2376. Published online 2006 May 4. doi: 10.1038/sj.emboj.7601116

PMCID:: PMC1478167

Abstract Article PDF–531K

Select item 700039515.

The transcription factor Foxd3 induces spinal cord ischemia-reperfusion injury by potentiating microRNA-214-dependent inhibition of Kcnk2

Ran Li, Kunchi Zhao, Qing Ruan, Chunyang Meng, Fei Yin

Exp Mol Med. 2020 Jan; 52(1): 118–129. Published online 2020 Jan 21. doi: 10.1038/s12276-019-0370-8

PMCID:: PMC7000395

Abstract Article PDF–1.9M

Select item 666565616.

TWIK-1 and TREK-1 Are Potassium Channels Contributing Significantly to Astrocyte Passive Conductance in Rat Hippocampal Slices

Min Zhou, Guangjin Xu, Minjie Xie, Xuexin Zhang, Gary P. Schools, Liqun Ma, Harold K. Kimelberg, Haijun Chen

J Neurosci. 2009 Jul 1; 29(26): 8551–8564. doi: 10.1523/JNEUROSCI.5784-08.2009

PMCID:: PMC6665656

Abstract Article PDF–6.2M

Select item 603539517.

Characterization of temperature-sensitive leak K⁺ currents and expression of TRAAK, TREK-1, and TREK2 channels in dorsal root ganglion neurons of rats

Viacheslav Viatchenko-Karpinski, Jennifer Ling, Jianguo G. Gu

Mol Brain. 2018; 11: 40. Published online 2018 Jul 6. doi: 10.1186/s13041-018-0384-5

PMCID:: PMC6035395

Abstract Article PDF–1.0M

Select item 271609818.

cGMP does not activate two-pore domain K⁺ channels in cerebrovascular smooth muscle

Eric E. Lloyd, Sean P. Marrelli, Robert M. Bryan, Jr.

Am J Physiol Heart Circ Physiol. 2009 Jun; 296(6): H1774–H1780. Published online 2009 Apr 10. doi: 10.1152/ajpheart.00082.2009

PMCID:: PMC2716098

Abstract Article

Select item 229018819.

Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2

Wenli Gu, Günter Schlichthörl, Jochen R Hirsch, Hartmut Engels, Christine Karschin, Andreas Karschin, Christian Derst, Ortrud K Steinlein, Jürgen Daut

J Physiol. 2002 Mar 15; 539(Pt 3): 657–668. doi: 10.1113/jphysiol.2001.013432