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Select item 56413351.

Improved Progression-Free Survival in Irinotecan-Treated Metastatic Colorectal Cancer Patients Carrying the HNF1A Coding Variant p.I27L

Adrien Labriet, Elena De Mattia, Erika Cecchin, Éric Lévesque, Derek Jonker, Félix Couture, Angela Buonadonna, Mario D’Andrea, Lyne Villeneuve, Giuseppe Toffoli, Chantal Guillemette

Front Pharmacol. 2017; 8: 712. Published online 2017 Oct 10. doi: 10.3389/fphar.2017.00712

PMCID:: PMC5641335

Abstract Article PDF–2.3M

Select item 41514852.

A Polymorphism in Hepatocyte Nuclear Factor 1 Alpha, rs7310409, Is Associated with Left Main Coronary Artery Disease

Rui Liu, Hanning Liu, Haiyong Gu, Xiao Teng, Yu Nie, Zhou Zhou, Yan Zhao, Shengshou Hu, Zhe Zheng

Biochem Res Int. 2014; 2014: 924105. Published online 2014 Aug 18. doi: 10.1155/2014/924105

PMCID:: PMC4151485

Abstract Article PDF–669K

Select item 28403993.

HNF1 AND HYPERTENSIVE NEPHROPATHY

Renata I. Dmitrieva, Cruz A. Hinojos, Eric Boerwinkle, Michael C. Braun, Myriam Fornage, Peter A. Doris

Hypertension. Author manuscript; available in PMC 2010 Mar 17.

Published in final edited form as: Hypertension. 2008 Jun; 51(6): 1583–1589. Published online 2008 Apr 28. doi: 10.1161/HYPERTENSIONAHA.108.110163

PMCID:: PMC2840399

Abstract Article PDF–1.0M

Select item 12238944.

Decreased expression levels of rat liver glutathione S-transferase A2 and albumin during the acute phase response are mediated by HNF1 (hepatic nuclear factor 1) and IL6DEX-NP.

Richard Whalen, Susan H Voss, Thomas D Boyer

Biochem J. 2004 Feb 1; 377(Pt 3): 763–768. doi: 10.1042/BJ20031256

PMCID:: PMC1223894

Summary PDF–153K

Select item 4133995.

The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding.

T A Ceska, M Lamers, P Monaci, A Nicosia, R Cortese, D Suck

EMBO J. 1993 May; 12(5): 1805–1810. doi: 10.2210/pdb1lfb/pdb

PMCID:: PMC413399

Summary Page Browse PDF–1.7M

Select item 4133986.

The three-dimensional NMR-solution structure of the polypeptide fragment 195-286 of the LFB1/HNF1 transcription factor from rat liver comprises a nonclassical homeodomain.

B Leiting, R De Francesco, L Tomei, R Cortese, G Otting, K Wüthrich

EMBO J. 1993 May; 12(5): 1797–1803. doi: 10.1002/j.1460-2075.1993.tb05827.x

PMCID:: PMC413398

Summary Page Browse PDF–1.4M

Select item 3323257.

A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain.

T Chouard, M Blumenfeld, I Bach, J Vandekerckhove, S Cereghini, M Yaniv

Nucleic Acids Res. 1990 Oct 11; 18(19): 5853–5863. doi: 10.1093/nar/18.19.5853

PMCID:: PMC332325

Summary Page Browse PDF–2.3M

Select item 3319448.

LFB1/HNF1 acts as a repressor of its own transcription.

G Piaggio, L Tomei, C Toniatti, R De Francesco, J Gerstner, R Cortese

Nucleic Acids Res. 1994 Oct 11; 22(20): 4284–4290. doi: 10.1093/nar/22.20.4284

PMCID:: PMC331944

Summary Page Browse PDF–1.6M

Select item 66811399.

Association of the HNF1A polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke

Yi‐Jiang Zhou, Rui‐Xing Yin, Shao‐Cai Hong, Qian Yang, Xiao‐Li Cao, Wu‐Xian Chen

J Gene Med. 2017 Jan-Feb; 19(1-2): e2941. Published online 2017 Feb 1. doi: 10.1002/jgm.2941

PMCID:: PMC6681139

Abstract Article PDF–201K

Select item 302279710.

HNF1A G319S variant, active cigarette smoking and incident type 2 diabetes in Aboriginal Canadians: a population-based epidemiological study

Sylvia H Ley, Robert A Hegele, Stewart B Harris, Mary Mamakeesick, Henian Cao, Philip W Connelly, Joel Gittelsohn, Ravi Retnakaran, Bernard Zinman, Anthony J Hanley

BMC Med Genet. 2011; 12: 1. Published online 2011 Jan 5. doi: 10.1186/1471-2350-12-1

PMCID:: PMC3022797

Abstract Article PDF–194K

Select item 292921911.

Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

Sylvia H Ley, Robert A Hegele, Philip W Connelly, Stewart B Harris, Mary Mamakeesick, Henian Cao, Joel Gittelsohn, Ravi Retnakaran, Bernard Zinman, Anthony J Hanley

Cardiovasc Diabetol. 2010; 9: 39. Published online 2010 Aug 18. doi: 10.1186/1475-2840-9-39

PMCID:: PMC2929219

Abstract Article PDF–256K

Select item 271931712.

Mitochondrial Dysfunction Contributes to Impaired Insulin Secretion in INS-1 Cells with Dominant-negative Mutations of HNF-1α and in HNF-1α-deficient Islets

Rebecca L. Pongratz, Richard G. Kibbey, Clare L. Kirkpatrick, Xiaojian Zhao, Marco Pontoglio, Moshe Yaniv, Claes B. Wollheim, Gerald I. Shulman, Gary W. Cline

J Biol Chem. 2009 Jun 19; 284(25): 16808–16821. Published online 2009 Apr 17. doi: 10.1074/jbc.M807723200

PMCID:: PMC2719317

Abstract Article PDF–1.0M

Select item 219353113.

Hepatocyte Nuclear Factor 1α Controls the Expression of Terminal Complement Genes

Marco Pontoglio, Mario Pausa, Antonia Doyen, Benoit Viollet, Moshe Yaniv, Francesco Tedesco

J Exp Med. 2001 Dec 3; 194(11): 1683–1690. doi: 10.1084/jem.194.11.1683

PMCID:: PMC2193531

Abstract Article PDF–167K

Select item 50880914.

Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.

M Pontoglio, S Sreenan, M Roe, W Pugh, D Ostrega, A Doyen, A J Pick, A Baldwin, G Velho, P Froguel, M Levisetti, S Bonner-Weir, G I Bell, M Yaniv, K S Polonsky

J Clin Invest. 1998 May 15; 101(10): 2215–2222. doi: 10.1172/JCI2548

PMCID:: PMC508809

Summary PDF–423K

Select item 33412615.

Structure of the gene encoding hepatocyte nuclear factor 1 (HNF1).

I Bach, M Pontoglio, M Yaniv

Nucleic Acids Res. 1992 Aug 25; 20(16): 4199–4204. doi: 10.1093/nar/20.16.4199

PMCID:: PMC334126

Summary Page Browse PDF–1011K

Select item 30202916.

Molecular targets of a human HNF1α mutation responsible for pancreatic β-cell dysfunction

Haiyan Wang, Peter A. Antinozzi, Kerstin A. Hagenfeldt, Pierre Maechler, Claes B. Wollheim

EMBO J. 2000 Aug 15; 19(16): 4257–4264. doi: 10.1093/emboj/19.16.4257

PMCID:: PMC302029

Abstract Article PDF–404K

Select item 11068417.

Laron Dwarfism and Non-Insulin-Dependent Diabetes Mellitus in the Hnf-1α Knockout Mouse

Ying-Hue Lee, Brian Sauer, Frank J. Gonzalez

Mol Cell Biol. 1998 May; 18(5): 3059–3068. doi: 10.1128/mcb.18.5.3059

PMCID:: PMC110684

Abstract Article PDF–3.3M

Select item 609650018.

Hepatocyte nuclear factors as possible C-reactive protein transcriptional inducer in the liver and white adipose tissue of rats with experimental chronic renal failure

Elzbieta Sucajtys-Szulc, Alicja Debska-Slizien, Boleslaw Rutkowski, Ryszard Milczarek, Iwona Pelikant-Malecka, Tomasz Sledzinski, Julian Swierczynski, Marek Szolkiewicz

Mol Cell Biochem. 2018; 446(1): 11–23. Published online 2018 Jan 12. doi: 10.1007/s11010-018-3268-1

PMCID:: PMC6096500

Abstract Article PDF–1.1M

Select item 313832519.

Bone Morphogenetic Protein 3 Controls Insulin Gene Expression and Is Down-regulated in INS-1 Cells Inducibly Expressing a Hepatocyte Nuclear Factor 1A–Maturity-onset Diabetes of the Young Mutation

Caroline Bonner, Angela M. Farrelly, Caoimhín G. Concannon, Heiko Dussmann, Mathurin Baquié, Isabelle Virard, Hella Wobser, Donat Kögel, Claes B. Wollheim, Marjan Rupnik, Maria M. Byrne, Hans-Georg König, Jochen H. M. Prehn

J Biol Chem. 2011 Jul 22; 286(29): 25719–25728. Published online 2011 May 31. doi: 10.1074/jbc.M110.215525