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Select item 78706781.

Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis

Sha Xu, Hui Tao, Wei Cao, Li Cao, Yan Lin, Shi-Min Zhao, Wei Xu, Jing Cao, Jian-Yuan Zhao

Signal Transduct Target Ther. 2021; 6: 54. Published online 2021 Feb 9. doi: 10.1038/s41392-020-00411-4

PMCID:: PMC7870678

Abstract Article PDF–3.3M

Select item 69552392.

Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7

Qi Chen, Yu Liu, Xueyan Ding, Qinfeng Li, Fuyu Qiu, Meihui Wang, Zhida Shen, Hao Zheng, Guosheng Fu

Mol Cell Biochem. 2020; 465(1): 103–114. Published online 2019 Dec 19. doi: 10.1007/s11010-019-03671-z

PMCID:: PMC6955239

Abstract Article PDF–3.8M

Select item 68124843.

A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7

Wesley Wei Wang, Maria Angulo-Ibanez, Jie Lyu, Yadagiri Kurra, Zhen Tong, Bo Wu, Ling Zhang, Vangmayee Sharma, Jennifer Zhou, Hening Lin, Yi Qin Gao, Wei Li, Katrin F. Chua, Wenshe Ray Liu

J Am Chem Soc. Author manuscript; available in PMC 2019 Oct 24.

Published in final edited form as: J Am Chem Soc. 2019 Feb 13; 141(6): 2462–2473. Published online 2019 Feb 4. doi: 10.1021/jacs.8b12083

PMCID:: PMC6812484

Abstract Article PDF–2.2M

Select item 56369754.

Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway

Erman E M Chen, Wei Zhang, Chenyi C Y Ye, Xiang Gao, Liangjun L J Jiang, Tengfei T F Zhao, Zhijun Z J Pan, Deting D T Xue

Cell Death Dis. 2017 Sep; 8(9): e3042. Published online 2017 Sep 7. doi: 10.1038/cddis.2017.429

PMCID:: PMC5636975

Abstract Article PDF–4.6M

Select item 49617945.

SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability

Lei Li, Lan Shi, Shangda Yang, Ruorong Yan, Di Zhang, Jianguo Yang, Lin He, Wanjin Li, Xia Yi, Luyang Sun, Jing Liang, Zhongyi Cheng, Lei Shi, Yongfeng Shang, Wenhua Yu

Nat Commun. 2016; 7: 12235. Published online 2016 Jul 20. doi: 10.1038/ncomms12235

PMCID:: PMC4961794

Abstract Article PDF–3.2M

Select item 48507366.

SIRT7 is activated by DNA and deacetylates histone H3 in the chromatin context

Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin

ACS Chem Biol. Author manuscript; available in PMC 2017 Mar 18.

Published in final edited form as: ACS Chem Biol. 2016 Mar 18; 11(3): 742–747. Published online 2016 Mar 3. doi: 10.1021/acschembio.5b01084

PMCID:: PMC4850736

Abstract Article PDF–480K

Select item 67358647.

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

Berta N Vazquez, Joshua K Thackray, Nicolas G Simonet, Sanjay Chahar, Noriko Kane-Goldsmith, Simon J Newkirk, Suman Lee, Jinchuan Xing, Michael P Verzi, Wenfeng An, Alejandro Vaquero, Jay A Tischfield, Lourdes Serrano

Nucleic Acids Res. 2019 Sep 5; 47(15): 7870–7885. Published online 2019 Jun 21. doi: 10.1093/nar/gkz519

PMCID:: PMC6735864

Abstract Article PDF–2.2M

Select item 64369268.

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

Ming Tang, Zhiming Li, Chaohua Zhang, Xiaopeng Lu, Bo Tu, Ziyang Cao, Yinglu Li, Yongcan Chen, Lu Jiang, Hui Wang, Lina Wang, Jiadong Wang, Baohua Liu, Xingzhi Xu, Haiying Wang, Wei-Guo Zhu

Sci Adv. 2019 Mar; 5(3): eaav1118. Published online 2019 Mar 27. doi: 10.1126/sciadv.aav1118

PMCID:: PMC6436926

Abstract Article PDF–4.6M

Select item 54594269.

Enhanced expression and phosphorylation of Sirt7 activates smad2 and ERK signaling and promotes the cardiac fibrosis differentiation upon angiotensin-II stimulation

Haichen Wang, Shengwu Liu, Shengqiang Liu, Wei Wei, Xiaolong Zhou, Fang Lin, Juanjuan Wang, Jinye Chen, Guodong Zhang, Yongbing Pang

PLoS One. 2017; 12(6): e0178530. Published online 2017 Jun 5. doi: 10.1371/journal.pone.0178530

PMCID:: PMC5459426

Abstract Article PDF–19M

Select item 488421110.

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

Berta N Vazquez, Joshua K Thackray, Nicolas G Simonet, Noriko Kane‐Goldsmith, Paloma Martinez‐Redondo, Trang Nguyen, Samuel Bunting, Alejandro Vaquero, Jay A Tischfield, Lourdes Serrano

EMBO J. 2016 Jul 15; 35(14): 1488–1503. Published online 2016 May 25. doi: 10.15252/embj.201593499

PMCID:: PMC4884211

Abstract Article PDF–2.8M

Select item 271443311.

Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis

Alice Grob, Pascal Roussel, Jane E. Wright, Brian McStay, Danièle Hernandez-Verdun, Valentina Sirri

J Cell Sci. 2009 Feb 15; 122(4): 489–498. Published online 2009 Jan 27. doi: 10.1242/jcs.042382

PMCID:: PMC2714433

Abstract Article

Select item 628078812.

Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis

Wei‐Wei Yan, Yun‐Liu Liang, Qi‐Xiang Zhang, Di Wang, Ming‐Zhu Lei, Jia Qu, Xiang‐Huo He, Qun‐Ying Lei, Yi‐Ping Wang

EMBO Rep. 2018 Dec; 19(12): e46377. Published online 2018 Nov 12. doi: 10.15252/embr.201846377

PMCID:: PMC6280788

Abstract Article PDF–2.9M

Select item 538953813.

SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription

Maximilian F. Blank, Sifan Chen, Fabian Poetz, Martina Schnölzer, Renate Voit, Ingrid Grummt

Nucleic Acids Res. 2017 Mar 17; 45(5): 2675–2686. Published online 2017 Jan 30. doi: 10.1093/nar/gkx053

PMCID:: PMC5389538

Abstract Article PDF–2.2M

Select item 341214314.

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

Matthew F. Barber, Eriko Michishita-Kioi, Yuanxin Xi, Luisa Tasselli, Mitomu Kioi, Zarmik Moqtaderi, Ruth I. Tennen, Silvana Paredes, Nicolas L. Young, Kaifu Chen, Kevin Struhl, Benjamin A. Garcia, Or Gozani, Wei Li, Katrin F. Chua

Nature. Author manuscript; available in PMC 2013 Jan 5.

Published in final edited form as: Nature. 2012 Jul 5; 487(7405): 114–118. doi: 10.1038/nature11043

PMCID:: PMC3412143

Abstract Article PDF–1.3M

Select item 605336915.

SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix

Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta, Kazuya Yamagata

Nat Commun. 2018; 9: 2833. Published online 2018 Jul 19. doi: 10.1038/s41467-018-05187-4

PMCID:: PMC6053369

Abstract Article PDF–2.0M

Select item 558065716.

SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability

Chenlin Song, Agnes Hotz-Wagenblatt, Renate Voit, Ingrid Grummt

Genes Dev. 2017 Jul 1; 31(13): 1370–1381. doi: 10.1101/gad.300624.117

PMCID:: PMC5580657

Abstract Article PDF–7.3M

Select item 849411017.

SIRT7 promotes chromosome synapsis during prophase I of female meiosis

Berta N. Vazquez, Cecilia S. Blengini, Yurdiana Hernandez, Lourdes Serrano, Karen Schindler

Chromosoma. Author manuscript; available in PMC 2021 Oct 6.

Published in final edited form as: Chromosoma. 2019 Sep; 128(3): 369–383. Published online 2019 Jun 29. doi: 10.1007/s00412-019-00713-9

PMCID:: PMC8494110

Abstract Article PDF–2.5M

Select item 555519018.

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis

Lu Jiang, Jiannan Xiong, Junsi Zhan, Fengjie Yuan, Ming Tang, Chaohua Zhang, Ziyang Cao, Yongcan Chen, Xiaopeng Lu, Yinglu Li, Hui Wang, Lina Wang, Jiadong Wang, Wei-Guo Zhu, Haiying Wang

J Biol Chem. 2017 Aug 11; 292(32): 13296–13311. Published online 2017 Jun 27. doi: 10.1074/jbc.M117.780130

PMCID:: PMC5555190

Abstract Article PDF–4.1M

Select item 123706919.

Evolutionarily Conserved and Nonconserved Cellular Localizations and Functions of Human SIRT Proteins

Eriko Michishita, Jean Y. Park, Jenna M. Burneskis, J. Carl Barrett, Izumi Horikawa

Mol Biol Cell. 2005 Oct; 16(10): 4623–4635. doi: 10.1091/mbc.E05-01-0033

PMCID:: PMC1237069

Abstract Article PDF–901K

Select item 299751620.

Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

Alessia Peserico, Cristiano Simone

J Biomed Biotechnol. 2011; 2011: 371832. Published online 2010 Dec 5. doi: 10.1155/2011/371832

PMCID:: PMC2997516

Abstract Article PDF–827K

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