PMC Links for Gene (Select 363578) - PMC

Select item 76953771.

Tim-3 deteriorates neuroinflammatory and neurocyte apoptosis after subarachnoid hemorrhage through the Nrf2/HMGB1 signaling pathway in rats

Shenquan Guo, Yuanzhi Li, Boyang Wei, Wenchao Liu, Ran Li, Wenping Cheng, Xin Zhang, Xuying He, Xifeng Li, Chuanzhi Duan

Aging (Albany NY) 2020 Nov 15; 12(21): 21161–21185. Published online 2020 Nov 7. doi: 10.18632/aging.103796

PMCID:: PMC7695377

Abstract Article PDF–3.0M

Select item 42133192.

Tim-3 cell signaling and iNOS are involved in the protective effects of ischemic postconditioning against focal ischemia in rats

Dingtai Wei, Xiaoxing Xiong, Heng Zhao

Metab Brain Dis. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Metab Brain Dis. 2015 Apr; 30(2): 483–490. Published online 2014 Apr 29. doi: 10.1007/s11011-014-9543-2

PMCID:: PMC4213319

Abstract Article PDF–1.2M

Select item 65157093.

Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral hemorrhage in rats

Zhou‐Qing Chen, Hao Yu, Hai‐Ying Li, Hai‐Tao Shen, Xiang Li, Ju‐Yi Zhang, Zhu‐Wei Zhang, Zhong Wang, Gang Chen

CNS Neurosci Ther. 2019 Jun; 25(6): 674–684. Published online 2019 Jan 24. doi: 10.1111/cns.13100

PMCID:: PMC6515709

Abstract Article PDF–1.9M

Select item 42064314.

Tim-3 Negatively Mediates Natural Killer Cell Function in LPS-Induced Endotoxic Shock

Hongyan Hou, Weiyong Liu, Shiji Wu, Yanjun Lu, Jing Peng, Yaowu Zhu, Yanfang Lu, Feng Wang, Ziyong Sun

PLoS One. 2014; 9(10): e110585. Published online 2014 Oct 22. doi: 10.1371/journal.pone.0110585

PMCID:: PMC4206431

Abstract Article PDF–3.1M

Select item 39656395.

Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection

Jacob V. Gorman, Gabriel Starbeck-Miller, Nhat-Long L. Pham, Geri L. Traver, Paul B. Rothman, John T. Harty, John D. Colgan

J Immunol. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: J Immunol. 2014 Apr 1; 192(7): 3133–3142. Published online 2014 Feb 24. doi: 10.4049/jimmunol.1302290

PMCID:: PMC3965639

Abstract Article PDF–2.5M

Select item 21186086.

Th2-driven, allergen-induced airway inflammation is reduced after treatment with anti–Tim-3 antibody in vivo

Jennifer Kearley, Sarah J. McMillan, Clare M. Lloyd

J Exp Med. 2007 Jun 11; 204(6): 1289–1294. doi: 10.1084/jem.20062093

PMCID:: PMC2118608

Abstract Article PDF–1.2M

Select item 46196107.

TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway

Brian Tomkowicz, Eileen Walsh, Adam Cotty, Raluca Verona, Nina Sabins, Fred Kaplan, Sandy Santulli-Marotto, Chen-Ni Chin, Jill Mooney, Russell B. Lingham, Michael Naso, Timothy McCabe

PLoS One. 2015; 10(10): e0140694. Published online 2015 Oct 22. doi: 10.1371/journal.pone.0140694

PMCID:: PMC4619610

Abstract Article PDF–1.7M

Select item 42149298.

T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) is recruited to the immune synapse, disrupts stable synapse formation and associates with receptor phosphatases

Kiera L. Clayton, Matthew S. Haaland, Matthew B. Douglas-Vail, Shariq Mujib, Glen M. Chew, Lishomwa C. Ndhlovu, Mario A. Ostrowski

J Immunol. Author manuscript; available in PMC 2015 Jan 15.

Published in final edited form as: J Immunol. 2014 Jan 15; 192(2): 782–791. Published online 2013 Dec 13. doi: 10.4049/jimmunol.1302663

PMCID:: PMC4214929

Abstract Article PDF–1.5M

Select item 50419729.

Genetic polymorphisms of immune checkpoint proteins PD-1 and TIM-3 are associated with survival of patients with hepatitis B virus-related hepatocellular carcinoma

Zhu Li, Na Li, Fang Li, Zhihua Zhou, Jiao Sang, Zhao Jin, Huihui Liu, Qunying Han, Yi Lv, Zhengwen Liu

Oncotarget. 2016 May 3; 7(18): 26168–26180. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8435

PMCID:: PMC5041972

Abstract Article PDF–4.2M

Select item 471167710.

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal–fetal interface in early pregnancy

Yan-Hong Li, Wen-Hui Zhou, Yu Tao, Song-Cun Wang, Yun-Lan Jiang, Di Zhang, Hai-Lan Piao, Qiang Fu, Da-Jin Li, Mei-Rong Du

Cell Mol Immunol. 2016 Jan; 13(1): 73–81. Published online 2015 Jan 12. doi: 10.1038/cmi.2014.126

PMCID:: PMC4711677

Abstract Article PDF–1.8M

Select item 296458011.

Tim3 binding to galectin-9 stimulates antimicrobial immunity

Pushpa Jayaraman, Isabel Sada-Ovalle, Sarah Beladi, Ana C. Anderson, Valerie Dardalhon, Chie Hotta, Vijay K. Kuchroo, Samuel M. Behar

J Exp Med. 2010 Oct 25; 207(11): 2343–2354. doi: 10.1084/jem.20100687

PMCID:: PMC2964580

Abstract Article PDF–1.8M

Select item 429751912.

CEACAM1 regulates TIM–3–mediated tolerance and exhaustion

Yu-Hwa Huang, Chen Zhu, Yasuyuki Kondo, Ana C. Anderson, Amit Gandhi, Andrew Russell, Stephanie K. Dougan, Britt-Sabina Petersen, Espen Melum, Thomas Pertel, Kiera L. Clayton, Monika Raab, Qiang Chen, Nicole Beauchemin, Paul J. Yazaki, Michal Pyzik, Mario A. Ostrowski, Jonathan N. Glickman, Christopher E. Rudd, Hidde L. Ploegh, Andre Franke, Gregory A. Petsko, Vijay K. Kuchroo, Richard S. Blumberg

Nature. Author manuscript; available in PMC 2015 Jan 17.

Published in final edited form as: Nature. 2015 Jan 15; 517(7534): 386–390. Published online 2014 Oct 26. doi: 10.1038/nature13848

Correction in:: Nature. 2016 Aug 18; 536(7616): 359.

PMCID:: PMC4297519

Abstract Article PDF–4.9M

Select item 362245313.

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

Shigeki Chiba, Muhammad Baghdadi, Hisaya Akiba, Hironori Yoshiyama, Ichiro Kinoshita, Hirotoshi Dosaka-Akita, Yoichiro Fujioka, Yusuke Ohba, Jacob V Gorman, John D Colgan, Mitsuomi Hirashima, Toshimitsu Uede, Akinori Takaoka, Hideo Yagita, Masahisa Jinushi

Nat Immunol. Author manuscript; available in PMC 2013 Apr 10.

Published in final edited form as: Nat Immunol. 2012 Sep; 13(9): 832–842. Published online 2012 Jul 29. doi: 10.1038/ni.2376

PMCID:: PMC3622453

Abstract Article PDF–4.2M

Select item 421932314.

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

Chuan Wu, Theresa Thalhamer, Rafael F. Franca, Sheng Xiao, Chao Wang, Chie Hotta, Chen Zhu, Mitsuomi Hirashima, Ana C. Anderson, Vijay K. Kuchroo

Immunity. Author manuscript; available in PMC 2015 Aug 21.

Published in final edited form as: Immunity. 2014 Aug 21; 41(2): 270–282. Published online 2014 Jul 24. doi: 10.1016/j.immuni.2014.06.011

PMCID:: PMC4219323

Abstract Article PDF–2.4M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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