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Items: 1 to 20 of 62

1.
Control of Voltage-Independent Zinc Inhibition of NMDA Receptors by the NR1 Subunit
Stephen F. Traynelis, Michele F. Burgess, Fang Zheng, Polina Lyuboslavsky, Jennifer L. Powers
J Neurosci. 1998 Aug 15; 18(16): 6163–6175. doi: 10.1523/JNEUROSCI.18-16-06163.1998
PMCID:
PMC6793196
AbstractArticlePDF–307K
2.
Functional Change of NMDA Receptors Related to Enhancement of Susceptibility to Neurotoxicity in the Developing Pontine Nucleus
Akira Mitani, Masahiko Watanabe, Kiyoshi Kataoka
J Neurosci. 1998 Oct 1; 18(19): 7941–7952. doi: 10.1523/JNEUROSCI.18-19-07941.1998
PMCID:
PMC6793002
AbstractArticlePDF–1.0M
3.
Neuronal Interleukin-16 (NIL-16): A Dual Function PDZ Domain Protein
Cornelia Kurschner, Michisuke Yuzaki
J Neurosci. 1999 Sep 15; 19(18): 7770–7780. doi: 10.1523/JNEUROSCI.19-18-07770.1999
PMCID:
PMC6782450
AbstractArticlePDF–604K
4.
Differential Expression of Glutamate Receptor Subunits in the Nervous System of Caenorhabditis elegans and Their Regulation by the Homeodomain Protein UNC-42
Penelope J. Brockie, David M. Madsen, Yi Zheng, Jerry Mellem, Andres V. Maricq
J Neurosci. 2001 Mar 1; 21(5): 1510–1522. doi: 10.1523/JNEUROSCI.21-05-01510.2001
PMCID:
PMC6762961
AbstractArticlePDF–1.4M
5.
20-Oxo-5β-Pregnan-3α-yl Sulfate Is a Use-Dependent NMDA Receptor Inhibitor
Milos Petrovic, Miloslav Sedlacek, Martin Horak, Hana Chodounska, Ladislav Vyklický, Jr
J Neurosci. 2005 Sep 14; 25(37): 8439–8450. doi: 10.1523/JNEUROSCI.1407-05.2005
PMCID:
PMC6725663
AbstractArticlePDF–386K
6.
Permeant Ion Effects on External Mg2+ Block of NR1/2D NMDA Receptors
Anqi Qian, Jon W. Johnson
J Neurosci. 2006 Oct 18; 26(42): 10899–10910. doi: 10.1523/JNEUROSCI.3453-06.2006
PMCID:
PMC6674757
AbstractArticlePDF–578K
7.
Isoform-specific Inhibition of N-methyl-D-aspartate Receptors by Bile Salts
Angela Koch, Michele Bonus, Holger Gohlke, Nikolaj Klöcker
Sci Rep. 2019; 9: 10068. Published online 2019 Jul 11. doi: 10.1038/s41598-019-46496-y
PMCID:
PMC6624251
AbstractArticlePDF–5.9M
8.
In the telencephalon, GluN2C NMDA receptor subunit mRNA is predominately expressed in glial cells and GluN2D mRNA in interneurons
Hassan A. Alsaad, Nicholas W. DeKorver, Zhihao Mao, Shashank M. Dravid, Jyothi Arikkath, Daniel T. Monaghan
Neurochem Res. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Neurochem Res. 2019 Jan; 44(1): 61–77. Published online 2018 Apr 12. doi: 10.1007/s11064-018-2526-7
PMCID:
PMC6349034
AbstractArticlePDF–4.7M
9.
Effects of Mg2+ on recovery of NMDA receptors from inhibition by memantine and ketamine reveal properties of a second site
Nathan G. Glasgow, Madeleine R. Wilcox, Jon W. Johnson
Neuropharmacology. Author manuscript; available in PMC 2019 Jul 15.
Published in final edited form as: Neuropharmacology. 2018 Jul 15; 137: 344–358. Published online 2018 May 12. doi: 10.1016/j.neuropharm.2018.05.017
PMCID:
PMC6050087
AbstractArticlePDF–1.6M
10.
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups
Riley Perszyk, Brooke M Katzman, Hirofumi Kusumoto, Steven A Kell, Matthew P Epplin, Yesim A Tahirovic, Rhonda L Moore, David Menaldino, Pieter Burger, Dennis C Liotta, Stephen F Traynelis
eLife. 2018; 7: e34711. Published online 2018 May 24. doi: 10.7554/eLife.34711
PMCID:
PMC5967867
AbstractArticlePDF–4.7M
11.
A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons
Sharon A. Swanger, Katie M. Vance, Timothy M. Acker, Sommer S. Zimmerman, John O. DiRaddo, Scott J. Myers, Christoffer Bundgaard, Cara A. Mosley, Samantha L. Summer, David S. Menaldino, Henrik S. Jensen, Dennis C. Liotta, Stephen F. Traynelis
ACS Chem Neurosci. Author manuscript; available in PMC 2019 Feb 21.
Published in final edited form as: ACS Chem Neurosci. 2018 Feb 21; 9(2): 306–319. Published online 2017 Nov 2. doi: 10.1021/acschemneuro.7b00329
PMCID:
PMC5924706
AbstractArticlePDF–819K
12.
The Structure Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-D-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-D-Aspartate Receptors
Katie L. Strong, Matthew P. Epplin, John Bacsa, Christopher J. Butch, Pieter B. Burger, David S. Menaldino, Stephen F. Traynelis, Dennis C. Liotta
J Med Chem. Author manuscript; available in PMC 2018 Jul 13.
Published in final edited form as: J Med Chem. 2017 Jul 13; 60(13): 5556–5585. Published online 2017 Jun 26. doi: 10.1021/acs.jmedchem.7b00239
PMCID:
PMC5916808
AbstractArticlePDF–1.3M
13.
Augmentation of anti-cancer drug efficacy in murine hepatocellular carcinoma cellsby aperipherally acting competitive N-methyl-D-aspartate (NMDA) receptor antagonist
Mikko Gynther, Ilaria Proietti Silvestri, Jacob C. Hansen, Kasper B. Hansen, Tarja Malm, Yevheniia Ishchenko, Younes Larsen, Liwei Han, Silke Kayser, Seppo Auriola, Aleksanteri Petsalo, Birgitte Nielsen, Darryl S. Pickering, Lennart Bunch
J Med Chem. Author manuscript; available in PMC 2018 Dec 14.
Published in final edited form as: J Med Chem. 2017 Dec 14; 60(23): 9885–9904. Published online 2017 Dec 5. doi: 10.1021/acs.jmedchem.7b01624
PMCID:
PMC5788303
AbstractArticlePDF–1.1M
14.
The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor
Thomas M. Kaiser, Steven A. Kell, Hirofumi Kusumoto, Gil Shaulsky, Subhrajit Bhattacharya, Matthew P. Epplin, Katie L. Strong, Eric J. Miller, Bryan D. Cox, David S. Menaldino, Dennis C. Liotta, Stephen F. Traynelis, Pieter B. Burger
Mol Pharmacol. 2018 Feb; 93(2): 141–156. Published online 2018 Feb. doi: 10.1124/mol.117.110940
PMCID:
PMC5767683
AbstractArticlePDF–2.5M
15.
Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits
Genevieve E. Lind, Tung-Chung Mou, Lucia Tamborini, Martin G. Pomper, Carlo De Micheli, Paola Conti, Andrea Pinto, Kasper B. Hansen
Proc Natl Acad Sci U S A. 2017 Aug 15; 114(33): E6942–E6951. Published online 2017 Jul 31. doi: 10.1073/pnas.1707752114
PMCID:
PMC5565460
AbstractArticlePDF–2.4M
16.
Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites
Alex R. Maolanon, Rune Risgaard, Shuang-Yan Wang, Yoran Snoep, Athanasios Papangelis, Feng Yi, David Holley, Anne F. Barslund, Niels Svenstrup, Kasper B. Hansen, Rasmus P. Clausen
ACS Chem Neurosci. Author manuscript; available in PMC 2018 Aug 16.
Published in final edited form as: ACS Chem Neurosci. 2017 Aug 16; 8(8): 1681–1687. Published online 2017 May 30. doi: 10.1021/acschemneuro.7b00117
PMCID:
PMC5559341
AbstractArticlePDF–2.0M
17.
Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site
Maja Jessen, Kristen Frederiksen, Feng Yi, Rasmus P. Clausen, Kasper B. Hansen, Hans Bräuner-Osborne, Paul Kilburn, Anders Damholt
Mol Pharmacol. 2017 Aug; 92(2): 151–161. Published online 2017 Aug. doi: 10.1124/mol.117.108944
Correction in:
Mol Pharmacol. 2018 Oct; 94(4): 1101–1102.
PMCID:
PMC5508192
AbstractArticlePDF–1.5M
18.
Development of Radiolabeled Ligands Targeting the Glutamate Binding Site of the N-Methyl-d-aspartate Receptor as Potential Imaging Agents for Brain
Lucia Tamborini, Ying Chen, Catherine A. Foss, Andrea Pinto, Andrew G. Horti, Stephen F. Traynelis, Carlo De Micheli, Ronnie C. Mease, Kasper B. Hansen, Paola Conti, Martin G. Pomper
J Med Chem. Author manuscript; available in PMC 2017 Dec 22.
Published in final edited form as: J Med Chem. 2016 Dec 22; 59(24): 11110–11119. Published online 2016 Dec 6. doi: 10.1021/acs.jmedchem.6b01344
PMCID:
PMC5484777
AbstractArticlePDF–606K
19.
Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology
Kevin K. Ogden, Wenjuan Chen, Sharon A. Swanger, Miranda J. McDaniel, Linlin Z. Fan, Chun Hu, Anel Tankovic, Hirofumi Kusumoto, Gabrielle J. Kosobucki, Anthony J. Schulien, Zhuocheng Su, Joseph Pecha, Subhrajit Bhattacharya, Slavé Petrovski, Adam E. Cohen, Elias Aizenman, Stephen F. Traynelis, Hongjie Yuan
PLoS Genet. 2017 Jan; 13(1): e1006536. Published online 2017 Jan 17. doi: 10.1371/journal.pgen.1006536
PMCID:
PMC5240934
AbstractArticlePDF–8.8M
20.
GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity
Riley E. Perszyk, John O. DiRaddo, Katie L. Strong, Chian-Ming Low, Kevin K. Ogden, Alpa Khatri, Geoffrey A. Vargish, Kenneth A. Pelkey, Ludovic Tricoire, Dennis C. Liotta, Yoland Smith, Chris J. McBain, Stephen F. Traynelis
Mol Pharmacol. 2016 Dec; 90(6): 689–702. Published online 2016 Dec. doi: 10.1124/mol.116.105130
PMCID:
PMC5118640
AbstractArticlePDF–2.1M

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