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Select item 107949291.

Bile duct ligation elevates 5-HT levels in cerebral cortex of rats partly due to impairment of brain UGT1A6 expression and activity via ammonia accumulation

Hanyu Yang, Linjun You, Zhongyan Wang, Lu Yang, Xun Wang, Wenhan Wu, Hao Zhi, Guangmei Rong, Yun Sheng, Xiaodong Liu, Li Liu

Redox Biol. 2024 Feb; 69: 103019. Published online 2023 Dec 28. doi: 10.1016/j.redox.2023.103019

PMCID:: PMC10794929

Abstract Article PDF–12M

Select item 59715172.

Correlations between polymorphisms in the uridine diphosphate-glucuronosyltransferase 1A and C-C motif chemokine receptor 5 genes and infection with the hepatitis B virus in three ethnic groups in China

Chan Zhang, Yan He, Ke-Ren Shan, Kui Tan, Ting Zhang, Chan-Juan Wang, Zhi-Zhong Guan

J Int Med Res. 2018 Feb; 46(2): 739–751. Published online 2017 Sep 20. doi: 10.1177/0300060517730174

PMCID:: PMC5971517

Abstract Article PDF–243K

Select item 59627293.

Yinchenhao Decoction Ameliorates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis in Rats by Regulating Phase II Metabolic Enzymes and Transporters

Ya-Xiong Yi, Yue Ding, Yong Zhang, Ning-Hui Ma, Feng Shi, Ping Kang, Zhen-Zhen Cai, Tong Zhang

Front Pharmacol. 2018; 9: 510. Published online 2018 May 15. doi: 10.3389/fphar.2018.00510

PMCID:: PMC5962729

Abstract Article PDF–3.5M

Select item 41743364.

Long-Term Reduction of Jaundice in Gunn Rats by Nonviral Liver-Targeted Delivery of Sleeping Beauty Transposon

Xia Wang, Debi P. Sarkar, Prashant Mani, Clifford J. Steer, Yong Chen, Chandan Guha, Voshavar Chandrasekhar, Arabinda Chaudhuri, Namita Roy-Chowdhury, Betsy T. Kren, Jayanta Roy-Chowdhury

Hepatology. Author manuscript; available in PMC 2014 Sep 24.

Published in final edited form as: Hepatology. 2009 Sep; 50(3): 815–824. doi: 10.1002/hep.23060

PMCID:: PMC4174336

Abstract Article PDF–415K

Select item 40881445.

Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients

Ada Piepoli, Annamaria Gentile, Maria Rosa Valvano, Daniela Barana, Cristina Oliani, Rosa Cotugno, Michele Quitadamo, Angelo Andriulli, Francesco Perri

World J Gastroenterol. 2006 Oct 21; 12(39): 6343–6348. Published online 2006 Oct 21. doi: 10.3748/wjg.v12.i39.6343

PMCID:: PMC4088144

Abstract Article PDF–715K

Select item 40497506.

Association between the low-dose irinotecan regimen-induced occurrence of grade 4 neutropenia and genetic variants of UGT1A1 in patients with gynecological cancers

HIROYUKI MORIYA, KATSUHIKO SAITO, NUALA HELSBY, SHIGEKAZU SUGINO, MICHIAKI YAMAKAGE, TAKERU SAWAGUCHI, MASAHIKO TAKASAKI, HIDENORI KATO, NAHOKO KUROSAWA

Oncol Lett. 2014 Jun; 7(6): 2035–2040. Published online 2014 Apr 8. doi: 10.3892/ol.2014.2046

PMCID:: PMC4049750

Abstract Article PDF–360K

Select item 37090077.

METABOLISM AND DISPOSITION OF ACETAMINOPHEN: RECENT ADVANCES IN RELATION TO HEPATOTOXICITY AND DIAGNOSIS

Mitchell R. McGill, Hartmut Jaeschke

Pharm Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Pharm Res. 2013 Sep; 30(9): 2174–2187. Published online 2013 Mar 6. doi: 10.1007/s11095-013-1007-6

PMCID:: PMC3709007

Abstract Article PDF–2.0M

Select item 35916528.

Enhanced Phase II Detoxification Contributes to Beneficial Effects of Dietary Restriction as Revealed by Multi-platform Metabolomics Studies

He Wen, Hye-ji Yang, Yong Jin An, Joon Mee Kim, Dae Hyun Lee, Xing Jin, Sung-woo Park, Kyung-Jin Min, Sunghyouk Park

Mol Cell Proteomics. 2013 Mar; 12(3): 575–586. Published online 2012 Dec 9. doi: 10.1074/mcp.M112.021352

PMCID:: PMC3591652

Abstract Article PDF–2.2M

Select item 33706769.

Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer

Giulia Bortolussi, Lorena Zentilin, Gabriele Baj, Pablo Giraudi, Cristina Bellarosa, Mauro Giacca, Claudio Tiribelli, Andrés F. Muro

FASEB J. 2012 Mar; 26(3): 1052–1063. doi: 10.1096/fj.11-195461

PMCID:: PMC3370676

Abstract Article

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303679811.

Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer

B Glimelius, H Garmo, Å Berglund, L A Fredriksson, M Berglund, H Kohnke, P Byström, H Sørbye, M Wadelius

Pharmacogenomics J. 2011 Feb; 11(1): 61–71. Published online 2010 Feb 23. doi: 10.1038/tpj.2010.10

PMCID:: PMC3036798

Abstract Article PDF–477K

Select item 282350012.

Modulation of the Human Glucuronosyltransferase UGT1A Pathway by Splice Isoform Polypeptides Is Mediated through Protein-Protein Interactions

Judith Bellemare, Mélanie Rouleau, Mario Harvey, Chantal Guillemette

J Biol Chem. 2010 Feb 5; 285(6): 3600–3607. Published online 2009 Dec 8. doi: 10.1074/jbc.M109.083139

PMCID:: PMC2823500

Abstract Article PDF–1.6M

Select item 253258713.

Disposition of Flavonoids via Enteric Recycling: Enzyme Stability Affects Characterization of Prunetin Glucuronidation across Species, Organs, and UGT Isoforms

Tiby B. Joseph, Stephen W.J. Wang, Xing Liu, Kaustubh H. Kulkarni, Jingrong Wang, Haiyan Xu, Ming Hu

Mol Pharm. Author manuscript; available in PMC 2008 Nov 1.

Published in final edited form as: Mol Pharm. 2007; 4(6): 883–894. doi: 10.1021/mp700135a

PMCID:: PMC2532587

Abstract Article PDF–2.1M

Select item 242380414.

Regulation of the Rat UGT1A6 by Glucocorticoids Involves a Cryptic Glucocorticoid Response Element

K. C. Falkner, J. K. Ritter, R. A. Prough

Drug Metab Dispos. Author manuscript; available in PMC 2008 Nov 1.

Published in final edited form as: Drug Metab Dispos. 2008 Feb; 36(2): 409–417. Published online 2007 Nov 26. doi: 10.1124/dmd.107.018952

PMCID:: PMC2423804

Abstract Article PDF–636K

Select item 158173815.

Hereditary Acholuric Jaundice in the Rat

Charles Kenneth Gunn

Can Med Assoc J. 1944 Mar; 50(3): 230–237.

PMCID:: PMC1581738

Summary Page Browse PDF–1.5M

Select item 140315216.

Expression of UDP-Glucuronosyltransferase Isoform mRNAs during Inflammation and Infection in Mouse Liver and Kidney

Terrilyn A. Richardson, Melanie Sherman, Daniel Kalman, Edward T. Morgan

Drug Metab Dispos. Author manuscript; available in PMC 2007 Mar 1.

Published in final edited form as: Drug Metab Dispos. 2006 Mar; 34(3): 351–353. Published online 2005 Dec 8. doi: 10.1124/dmd.105.007435

PMCID:: PMC1403152

Abstract Article PDF–577K

Select item 137695017.

Splice-site mutations: a novel genetic mechanism of Crigler-Najjar syndrome type 1.

S Gantla, C T Bakker, B Deocharan, N R Thummala, J Zweiner, M Sinaasappel, J Roy Chowdhury, P J Bosma, N Roy Chowdhury

Am J Hum Genet. 1998 Mar; 62(3): 585–592. doi: 10.1086/301756

PMCID:: PMC1376950

Summary PDF–1.7M

Select item 121990818.

Molecular basis of bilirubin UDP-glucuronosyltransferase induction in spontaneously diabetic rats, acetone-treated rats and starved rats.

L Braun, M J Coffey, F Puskás, T Kardon, G Nagy, A A Conley, B Burchell, J Mandl

Biochem J. 1998 Dec 15; 336(Pt 3): 587–592. doi: 10.1042/bj3360587

PMCID:: PMC1219908

Summary PDF–152K

Select item 121859919.

A critical amino acid residue, asp446, in UDP-glucuronosyltransferase.

H Iwano, H Yokota, S Ohgiya, N Yotumoto, A Yuasa

Biochem J. 1997 Aug 1; 325(Pt 3): 587–591. doi: 10.1042/bj3250587

PMCID:: PMC1218599

Summary PDF–437K

Select item 115136720.

Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.

R Wooster, L Sutherland, T Ebner, D Clarke, O Da Cruz e Silva, B Burchell

Biochem J. 1991 Sep 1; 278(Pt 2): 465–469. doi: 10.1042/bj2780465

PMCID:: PMC1151367

Summary Page Browse PDF–1.0M

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