PMC Links for GEO Profiles (Select 101043201) - PMC

Select item 59915201.

A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells

Kei Fukuda, Akihiko Okuda, Kosuke Yusa, Yoichi Shinkai

Genome Res. 2018 Jun; 28(6): 846–858. doi: 10.1101/gr.227280.117

PMCID:: PMC5991520

Select item 50813952.

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex

Richard T. Timms, Iva A. Tchasovnikarova, Robin Antrobus, Gordon Dougan, Paul J. Lehner

Cell Rep. 2016 Oct 11; 17(3): 653–659. Published online 2016 Oct 11. doi: 10.1016/j.celrep.2016.09.050

PMCID:: PMC5081395

Abstract Article PDF–2.2M

Select item 49399203.

ATRX binds to atypical chromatin domains at the 3′ exons of zinc finger genes to preserve H3K9me3 enrichment

David Valle-García, Zulekha A. Qadeer, Domhnall S. McHugh, Flávia G. Ghiraldini, Asif H. Chowdhury, Dan Hasson, Michael A. Dyer, Félix Recillas-Targa, Emily Bernstein

Epigenetics. 2016 Jun; 11(6): 398–414. Published online 2016 Mar 30. doi: 10.1080/15592294.2016.1169351

PMCID:: PMC4939920

Abstract Article PDF–2.1M

Select item 40316364.

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

M Rodriguez-Paredes, A Martinez de Paz, L Simó-Riudalbas, S Sayols, C Moutinho, S Moran, A Villanueva, M Vázquez-Cedeira, P A Lazo, F Carneiro, C S Moura, J Vieira, M R Teixeira, M Esteller

Oncogene. 2014 May 22; 33(21): 2807–2813. Published online 2013 Jun 17. doi: 10.1038/onc.2013.239

PMCID:: PMC4031636

Abstract Article PDF–2.1M

Select item 39553485.

Histone methyltransferase SETDB1 is required for prostate cancer cell proliferation, migration and invasion

Yi Sun, Min Wei, Shan-Cheng Ren, Rui Chen, Wei-Dong Xu, Fu-Bo Wang, Ji Lu, Jian Shen, Yong-Wei Yu, Jian-Guo Hou, Chuan-Liang Xu, Jiao-Ti Huang, Ying-Hao Sun

Asian J Androl. 2014 Mar-Apr; 16(2): 319–324. Published online 2014 Feb 18. doi: 10.4103/1008-682X.122812

PMCID:: PMC3955348

Abstract Article PDF–2.3M

Select item 39494166.

A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype

Ryan W Serra, Minggang Fang, Sung Mi Park, Lloyd Hutchinson, Michael R Green

eLife. 2014; 3: e02313. Published online 2014 Mar 12. doi: 10.7554/eLife.02313

PMCID:: PMC3949416

Abstract Article PDF–5.2M

Select item 38610587.

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine

Mol Cell. Author manuscript; available in PMC 2013 Dec 12.

Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006

PMCID:: PMC3861058

Abstract Article PDF–2.1M

Select item 37798918.

Histone Methylation at H3K9; Evidence for a Restrictive Epigenome in Schizophrenia

Kayla A. Chase, David P. Gavin, Alessandro Guidotti, Rajiv P. Sharma

Schizophr Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Schizophr Res. 2013 Sep; 149(0): 15–20. Published online 2013 Jun 28. doi: 10.1016/j.schres.2013.06.021

PMCID:: PMC3779891

Abstract Article PDF–2.0M

Select item 36591889.

Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation and POMC gene expression in β-endorphin-producing POMC neurons of the hypothalamus

Rola A. Bekdash, Changqing Zhang, Dipak K. Sarkar

Alcohol Clin Exp Res. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Alcohol Clin Exp Res. 2013 Jul; 37(7): 1133–1142. Published online 2013 Feb 15. doi: 10.1111/acer.12082

PMCID:: PMC3659188

Abstract Article PDF–1.6M

Select item 352879810.

The Expanding Role of MBD Genes in Autism: Identification of a MECP2 Duplication and Novel Alterations in MBD5, MBD6, and SETDB1

Holly N. Cukier, Joycelyn M. Lee, Deqiong Ma, Juan I. Young, Vera Mayo, Brittany L. Butler, Sandhya S. Ramsook, Joseph A. Rantus, Alexander J. Abrams, Patrice L. Whitehead, Harry H. Wright, Ruth K. Abramson, Jonathan L. Haines, Michael L. Cuccaro, Margaret A. Pericak-Vance, John R. Gilbert

Autism Res. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Autism Res. 2012 Dec; 5(6): 385–397. Published online 2012 Oct 10. doi: 10.1002/aur.1251

PMCID:: PMC3528798

Abstract Article PDF–1.8M

Select item 341085911.

Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength

J. H. Duncan Bassett, Apostolos Gogakos, Jacqueline K. White, Holly Evans, Richard M. Jacques, Anne H. van der Spek, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Edward Ryder, David Sunter, Alan Boyde, Michael J. Campbell, Peter I. Croucher, Graham R. Williams

PLoS Genet. 2012 Aug; 8(8): e1002858. Published online 2012 Aug 2. doi: 10.1371/journal.pgen.1002858

PMCID:: PMC3410859

Abstract Article PDF–837K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302505613.

Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice

Yan Jiang, Anouch Matevossian, Yin Guo, Schahram Akbarian

Neuropharmacology. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Neuropharmacology. 2011 Jun; 60(7-8): 1088–1097. Published online 2010 Sep 30. doi: 10.1016/j.neuropharm.2010.09.020

PMCID:: PMC3025056

Abstract Article PDF–2.2M

Select item 174819514.

ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease

Hoon Ryu, Junghee Lee, Sean W. Hagerty, Byoung Yul Soh, Sara E. McAlpin, Kerry A. Cormier, Karen M. Smith, Robert J. Ferrante

Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50): 19176–19181. Published online 2006 Dec 1. doi: 10.1073/pnas.0606373103

PMCID:: PMC1748195

Abstract Article PDF–1.0M

Select item 35586915.

Histone H3-K9 Methyltransferase ESET Is Essential for Early Development

Jonathan E. Dodge, Yong-Kook Kang, Hideyuki Beppu, Hong Lei, En Li

Mol Cell Biol. 2004 Mar; 24(6): 2478–2486. doi: 10.1128/MCB.24.6.2478-2486.2004

PMCID:: PMC355869

Abstract Article PDF–955K

Select item 15235916.

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

David C. Schultz, Kasirajan Ayyanathan, Dmitri Negorev, Gerd G. Maul, Frank J. Rauscher, III

Genes Dev. 2002 Apr 15; 16(8): 919–932. doi: 10.1101/gad.973302

PMCID:: PMC152359

Abstract Article PDF–547K

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