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Items: 1 to 20 of 474

1.
CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer
Xueying Yuan, Xiaoxin Hao, Hilda L. Chan, Na Zhao, Diego A. Pedroza, Fengshuo Liu, Kang Le, Alex J. Smith, Sebastian J. Calderon, Nadia Lieu, Michael J. Soth, Philip Jones, Xiang H.F. Zhang, Jeffrey M. Rosen
JCI Insight. 2024 Oct 22; 9(20): e182621. Published online 2024 Sep 17. doi: 10.1172/jci.insight.182621
PMCID:
PMC11533985
AbstractArticlePDF–3.3M
2.
AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer
Sumaira Sardar, Christopher M. McNair, Lakshmi Ravindranath, Saswati N. Chand, Wei Yuan, Denisa Bogdan, Jon Welti, Adam Sharp, Natalie K. Ryan, Liam A. Knudsen, Matthew J. Schiewer, Elise G. DeArment, Thomas Janas, Xiaofeng A. Su, Lisa M. Butler, Johann S. de Bono, Kris Frese, Nigel Brooks, Neil Pegg, Karen E. Knudsen, Ayesha A. Shafi
Oncogene. 2024; 43(43): 3197–3213. Published online 2024 Sep 13. doi: 10.1038/s41388-024-03148-4
PMCID:
PMC11493679
AbstractArticlePDF–8.7M
3.
Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2024 Sep; 20(9): 1025–1048. Published online 2024 Jul 15. doi: 10.1038/s44320-024-00055-4
PMCID:
PMC11369174
AbstractArticlePDF–2.7M
4.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
5.
Nemo‐like kinase suppresses a wide range of transcription factors, including nuclear factor‐kB
Jun Yasuda, Hideki Yokoo, Tesshi Yamada, Issay Kitabayashi, Takao Sekiya, Hitoshi Ichikawa
Cancer Sci. 2004 Jan; 95(1): 52–57. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb03170.x
PMCID:
PMC11158368
AbstractArticlePDF–509K
6.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
7.
CREBBP and p300 lysine acetyl transferases in the DNA damage response
Ilaria Dutto, Claudia Scalera, Ennio Prosperi
Cell Mol Life Sci. 2018 Apr; 75(8): 1325–1338. Published online 2017 Nov 23. doi: 10.1007/s00018-017-2717-4
PMCID:
PMC11105205
AbstractArticlePDF–1015K
8.
BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion
Azadeh Ebrahimi, Andreas Waha, Jens Schittenhelm, Georg Gohla, Martin U Schuhmann, Torsten Pietsch
Acta Neuropathol Commun. 2024; 12: 60. Published online 2024 Apr 18. doi: 10.1186/s40478-024-01780-5
PMCID:
PMC11025138
AbstractArticlePDF–6.3M
9.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
10.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4
PMCID:
PMC10869800
AbstractArticlePDF–9.3M
11.
NOTCH1 and CREBBP co‐mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR‐mutated NSCLC: translational research of phase III IMPACT study
Satoshi Ikeda, Masahiro Tsuboi, Kazuko Sakai, Toshihiro Misumi, Hiroaki Akamatsu, Hiroyasu Shoda, Noriaki Sakakura, Atsushi Nakamura, Yasuhisa Ohde, Hidetoshi Hayashi, Kyoichi Okishio, Morihito Okada, Ichiro Yoshino, Jiro Okami, Kazuhisa Takahashi, Norihiko Ikeda, Masayuki Tanahashi, Yuichi Tambo, Haruhiro Saito, Shinichi Toyooka, Hidetoshi Inokawa, Toyofumi Chen‐Yoshikawa, Toshihide Yokoyama, Tatsuro Okamoto, Noriko Yanagitani, Masahide Oki, Makoto Takahama, Kenji Sawa, Hirohito Tada, Kazuhiko Nakagawa, Tetsuya Mitsudomi, Kazuto Nishio
Mol Oncol. 2024 Feb; 18(2): 305–316. Published online 2023 Oct 28. doi: 10.1002/1878-0261.13542
PMCID:
PMC10850799
AbstractArticlePDF–1.1M
12.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
13.
The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels
Monika Krošel, Marcel Gabathuler, Larissa Moser, Malgorzata Maciukiewicz, Thomas Züllig, Tanja Seifritz, Matija Tomšič, Oliver Distler, Caroline Ospelt, Kerstin Klein
Sci Rep. 2023; 13: 17112. Published online 2023 Oct 10. doi: 10.1038/s41598-023-44412-z
PMCID:
PMC10564874
AbstractArticlePDF–2.4M
14.
β-catenin/CBP activation of mTORC1 signaling promotes partial epithelial-mesenchymal states in head and neck cancer
Eric R. Reed, Stacy A. Jankowski, Anthony J. Spinella, Vikki Noonan, Robert Haddad, Kenichi Nomoto, Junji Matsui, Manish V. Bais, Xaralabos Varelas, Maria A. Kukuruzinska, Stefano Monti
Transl Res. Author manuscript; available in PMC 2024 Oct 1.
Published in final edited form as: Transl Res. 2023 Oct; 260: 46–60. Published online 2023 Jun 21. doi: 10.1016/j.trsl.2023.05.007
PMCID:
PMC10527608
AbstractArticlePDF–2.5M
15.
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4
Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang
Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5
PMCID:
PMC10460732
AbstractArticlePDF–5.6M
16.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
17.
Inhibition of USP7 induces p53-independent tumor growth suppression in triple-negative breast cancers by destabilizing FOXM1
Jingjie Yi, Huan Li, Bo Chu, Ning Kon, Xiaoping Hu, Jianping Hu, Yan Xiong, H. Umit Kaniskan, Jian Jin, Wei Gu
Cell Death Differ. 2023 Jul; 30(7): 1799–1810. Published online 2023 Jun 8. doi: 10.1038/s41418-023-01180-7
PMCID:
PMC10307817
AbstractArticlePDF–2.5M
18.
Regulation of RB1CC1/FIP200 stability and autophagy function by CREBBP-mediated acetylation in an intrinsically disordered region
Fei Yi, Chunmiao Cai, Banzhan Ruan, Mingang Hao, Syn Kok Yeo, Michael Haas, Fuchun Yang, Xiaoting Zhang, Jun-Lin Guan
Autophagy. 2023; 19(6): 1662–1677. Published online 2022 Nov 27. doi: 10.1080/15548627.2022.2148432
PMCID:
PMC10262773
AbstractArticlePDF–2.7M
19.
Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt
J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706
PMCID:
PMC10243116
AbstractArticlePDF–13M
20.
Hypermethylation at CREBBP Is Associated with Cognitive Impairment in a Mexican American Cohort
Ann Abraham Daniel, Talisa Silzer, Jie Sun, Zhengyang Zhou, Courtney Hall, Nicole Phillips, Robert Barber
J Alzheimers Dis. 2023; 92(4): 1229–1239. Prepublished online 2023 Mar 3. Published online 2023 Apr 18. doi: 10.3233/JAD-221031
PMCID:
PMC10200223
AbstractArticlePDF–293K

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