PMC Links for GEO Profiles (Select 106146549) - PMC

Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang

Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558

PMCID:: PMC10240998

Abstract Article PDF–4.4M

Select item 95332354.

Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage

Jingyue Jia, Fulong Wang, Zambarlal Bhujabal, Ryan Peters, Michal Mudd, Thabata Duque, Lee Allers, Ruheena Javed, Michelle Salemi, Christian Behrends, Brett Phinney, Terje Johansen, Vojo Deretic

J Cell Biol. 2022 Nov 7; 221(11): e202207091. Published online 2022 Sep 30. doi: 10.1083/jcb.202207091

PMCID:: PMC9533235

Abstract Article PDF–9.7M

Select item 94735545.

Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation

Rachel M. Jansen, Roberta Peruzzo, Simon A. Fromm, Adam L. Yokom, Roberto Zoncu, James H. Hurley

Sci Adv. 2022 Sep; 8(37): eadd2926. Published online 2022 Sep 14. doi: 10.1126/sciadv.add2926

PMCID:: PMC9473554

Abstract Article PDF–3.2M

Select item 91197366.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90147117.

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach

Cell Rep. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030

PMCID:: PMC9014711

Abstract Article PDF–2.2M

Select item 89082728.

HBXIP is a novel regulator of the unfolded protein response that sustains tamoxifen resistance in ER+ breast cancer

Shenghong Zhang, Ranran Wang, Xinyue Wang, Xueling Guo, Yanyan Du, Xin Guo, Xinlan Zong, Changhui Zhu, Xiaolei Zhou

J Biol Chem. 2022 Mar; 298(3): 101644. Published online 2022 Jan 28. doi: 10.1016/j.jbc.2022.101644

PMCID:: PMC8908272

Abstract Article PDF–3.3M

Select item 87919679.

The modulation of PD-L1 induced by the oncogenic HBXIP for breast cancer growth

Fei-fei Xu, Hui-min Sun, Run-ping Fang, Lu Zhang, Hui Shi, Xue Wang, Xue-li Fu, Xian-meng Li, Xu-he Shi, Yue Wu, Kai Ye, Wei-ying Zhang, Li-hong Ye

Acta Pharmacol Sin. 2022 Feb; 43(2): 429–445. Published online 2021 Apr 6. doi: 10.1038/s41401-021-00631-6

PMCID:: PMC8791967

Abstract Article PDF–7.3M

Select item 855290710.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 787717312.

Oncoprotein HBXIP promotes tumorigenesis through MAPK/ERK pathway activation in non-small cell lung cancer

Jun Zhang, Bei Sun, Xianhui Ruan, Xiukun Hou, Jingtai Zhi, Xiangrui Meng, Xiangqian Zheng, Ming Gao

Cancer Biol Med. 2021 Feb 15; 18(1): 105–119. Published online 2021 Feb 15. doi: 10.20892/j.issn.2095-3941.2020.0098

PMCID:: PMC7877173

Abstract Article PDF–1.8M

Select item 780357713.

HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification

Zhi Yang, Xiaodi Jiang, Deming Li, Xiaofeng Jiang

Aging (Albany NY) 2020 Dec 31; 12(24): 24967–24982. Published online 2020 Oct 13. doi: 10.18632/aging.103767

PMCID:: PMC7803577

Abstract Article PDF–2.5M

Select item 756688114.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 722982415.

The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth

Yue Wu, Xue Wang, Feifei Xu, Lu Zhang, Tianjiao Wang, Xueli Fu, Tianzhi Jin, Weiying Zhang, Lihong Ye

Nucleic Acids Res. 2020 May 21; 48(9): 4858–4876. Published online 2020 Apr 20. doi: 10.1093/nar/gkaa232

PMCID:: PMC7229824

Abstract Article PDF–14M

Select item 717640316.

Structural basis for the docking of mTORC1 on the lysosomal surface

Kacper B. Rogala, Xin Gu, Jibril F. Kedir, Monther Abu-Remaileh, Laura F. Bianchi, Alexia M. S. Bottino, Rikke Dueholm, Anna Niehaus, Daan Overwijn, Ange-Célia Priso Fils, Sherry X. Zhou, Daniel Leary, Nouf N. Laqtom, Edward J. Brignole, David M. Sabatini

Science. Author manuscript; available in PMC 2020 Apr 22.

Published in final edited form as: Science. 2019 Oct 25; 366(6464): 468–475. Published online 2019 Oct 10. doi: 10.1126/science.aay0166

PMCID:: PMC7176403

Abstract Article PDF–2.8M

Select item 716998317.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 679415818.

LZTR1 is a regulator of RAS ubiquitination and signaling

Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga

Science. Author manuscript; available in PMC 2019 Oct 15.

Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210

PMCID:: PMC6794158

Abstract Article PDF–1.9M

Select item 664311319.

Increased Expression of LAMTOR5 Predicts Poor Prognosis and Is Associated with Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma

Qi-Chao Yang, Cong- Cong Wu, Ling-Yun Cao, Yao Xiao, Hao Li, Bing Liu, Zhi-Jun Sun

Int J Med Sci. 2019; 16(6): 783–792. Published online 2019 Jun 2. doi: 10.7150/ijms.33415

PMCID:: PMC6643113

Abstract Article PDF–2.6M

Select item 646201620.

Oncoprotein HBXIP induces PKM2 via transcription factor E2F1 to promote cell proliferation in ER-positive breast cancer

Bo-wen Liu, Tian-jiao Wang, Lei-lei Li, Lu Zhang, Yun-xia Liu, Jin-yan Feng, Yue Wu, Fei-fei Xu, Quan-sheng Zhang, Ming-zhu Bao, Wei-ying Zhang, Li-hong Ye

Acta Pharmacol Sin. 2019 Apr; 40(4): 530–538. Published online 2018 Jun 20. doi: 10.1038/s41401-018-0015-9

PMCID:: PMC6462016

Abstract Article PDF–4.6M

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