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Select item 111314521.

Cathepsin X-mediated β₂ integrin activation results in nanotube outgrowth

N. Obermajer, Z. Jevnikar, B. Doljak, A. M. Sadaghiani, M. Bogyo, J. Kos

Cell Mol Life Sci. 2009 Mar; 66(6): 1126–1134. Published online 2009 Feb 6. doi: 10.1007/s00018-009-8829-8

PMCID:: PMC11131452

Abstract Article PDF–5.0M

Select item 110694862.

Cathepsin K deficiency prevented stress-related thrombosis in a mouse FeCl₃ model

Xueying Jin, Xueling Yue, Zhe Huang, Xiangkun Meng, Shengnan Xu, Yuna Wu, Ying Wan, Aiko Inoue, Megumi Narisawa, Lina Hu, Guo-Ping Shi, Hiroyuki Umegaki, Toyoaki Murohara, Yanna Lei, Masafumi Kuzuya, Xian Wu Cheng

Cell Mol Life Sci. 2024 Dec; 81(1): 205. Published online 2024 May 4. doi: 10.1007/s00018-024-05240-0

PMCID:: PMC11069486

Abstract Article PDF–5.1M

Select item 107004453.

mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy

Anna Caliò, Stefano Marletta, Giulio Settanni, Mimma Rizzo, Stefano Gobbo, Serena Pedron, Lavinia Stefanizzi, Enrico Munari, Matteo Brunelli, Lisa Marcolini, Anna Pesci, Stefano Fratoni, Francesco Pierconti, Maria Rosaria Raspollini, Antonio Marchetti, Claudio Doglioni, Mahul B. Amin, Camillo Porta, Guido Martignoni

Virchows Arch. 2023; 483(6): 821–833. Published online 2023 Nov 8. doi: 10.1007/s00428-023-03688-2

PMCID:: PMC10700445

Abstract Article PDF–1.9M

Select item 102095404.

Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation

Chengming Zhang, Zhiyi Liu, Xiaotian Wang, Bin Zhang, Licheng Cui, Qinghe Hu, Bin Hu, Kuan Cao, Wengang Shan, Hengliang Shi, Renhao Wang

iScience. 2023 Jun 16; 26(6): 106852. Published online 2023 May 9. doi: 10.1016/j.isci.2023.106852

PMCID:: PMC10209540

Abstract Article PDF–5.8M

Select item 98774375.

Lung macrophages utilize unique cathepsin K–dependent phagosomal machinery to degrade intracellular collagen

Ivo Fabrik, Orsolya Bilkei-Gorzo, Maria Öberg, Daniela Fabrikova, Johannes Fuchs, Carina Sihlbom, Melker Göransson, Anetta Härtlova

Life Sci Alliance. 2023 Apr; 6(4): e202201535. Published online 2023 Jan 25. doi: 10.26508/lsa.202201535

PMCID:: PMC9877437

Abstract Article PDF–1.8M

Select item 94999366.

Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer

Ning Wu, YouZhi Wang, KeKe Wang, BoQiang Zhong, YiHao Liao, JiaMing Liang, Ning Jiang

Cell Death Dis. 2022 Sep; 13(9): 813. Published online 2022 Sep 22. doi: 10.1038/s41419-022-05215-8

PMCID:: PMC9499936

Abstract Article PDF–4.9M

Select item 91063037.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 90346718.

Clinical and genetic characterization of three Russian patients with pycnodysostosis due to pathogenic variants in the CTSK gene

Tatiana Vladimirovna Markova, Vladimir Kenis, Evgeniy Melchenko, Darya Guseva, Darya Osipova, Nailya Galeeva, Tatiana Nagornova, Elena Leonidovna Dadali

Mol Genet Genomic Med. 2022 May; 10(5): e1904. Published online 2022 Mar 21. doi: 10.1002/mgg3.1904

PMCID:: PMC9034671

Abstract Article PDF–1.9M

Select item 86163809.

Cathepsin K Regulates Intraocular Pressure by Modulating Extracellular Matrix Remodeling and Actin-Bundling in the Trabecular Meshwork Outflow Pathway

Avinash Soundararajan, Sachin Anil Ghag, Sai Supriya Vuda, Ting Wang, Padmanabhan Paranji Pattabiraman

Cells. 2021 Nov; 10(11): 2864. Published online 2021 Oct 24. doi: 10.3390/cells10112864

PMCID:: PMC8616380

Abstract Article PDF–4.3M

Select item 858686210.

活化的Mir-30a-wnt/β-catenin信号轴通过上调组织蛋白酶K的表达促进牙周膜干细胞向成牙骨质细胞分化

刘芬, 周志斐, 薛洋, 朱斌, 吴补领, 陈发明

Nan Fang Yi Ke Da Xue Xue Bao. 2021 Oct 20; 41(10): 1439–1447. Chinese. doi: 10.12122/j.issn.1673-4254.2021.10.01

PMCID:: PMC8586862

Abstract Article PDF–1.4M

Select item 853554911.

Genetic and Molecular Evaluation: Reporting Three Novel Mutations and Creating Awareness of Pycnodysostosis Disease

Khalda Sayed Amr, Hala T. El-Bassyouni, Sawsan Abdel Hady, Mostafa I. Mostafa, Mennat I. Mehrez, Domenico Coviello, Ghada Y. El-Kamah

Genes (Basel) 2021 Oct; 12(10): 1552. Published online 2021 Sep 29. doi: 10.3390/genes12101552

PMCID:: PMC8535549

Abstract Article PDF–2.2M

Select item 848801512.

The CD200-CD200R axis promotes squamous cell carcinoma metastasis via regulation of cathepsin K

Iasha Z. Khan, Christina A. Del Guzzo, Anqi Shao, Jiyoon Cho, Rong Du, Adrienne O. Cohen, David M. Owens

Cancer Res. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Cancer Res. 2021 Oct 1; 81(19): 5021–5032. Published online 2021 Jun 28. doi: 10.1158/0008-5472.CAN-20-3251

PMCID:: PMC8488015

Abstract Article PDF–1.5M

Select item 818759313.

Regulatory properties of vitronectin and its glycosylation in collagen fibril formation and collagen-degrading enzyme cathepsin K activity

Kimie Date, Hiromi Sakagami, Kei Yura

Sci Rep. 2021; 11: 12023. Published online 2021 Jun 8. doi: 10.1038/s41598-021-91353-6

PMCID:: PMC8187593

Abstract Article PDF–3.6M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 813852315.

Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V

Keval Bollavaram, Tiffanie H. Leeman, Maggie W. Lee, Akhil Kulkarni, Sophia G. Upshaw, Jiabei Yang, Hannah Song, Manu O. Platt

Protein Sci. 2021 Jun; 30(6): 1131–1143. Published online 2021 Apr 15. doi: 10.1002/pro.4073

PMCID:: PMC8138523

Abstract Article PDF–6.0M

Select item 782820016.

Elevated Expression of Cathepsin K in Periodontal Ligament Fibroblast by Inflammatory Cytokines Accelerates Osteoclastogenesis via Paracrine Mechanism in Periodontal Disease

Soon Chul Heo, Yu Na Kim, YunJeong Choi, Ji-Young Joo, Jae Joon Hwang, Moon-Kyoung Bae, Hyung Joon Kim

Int J Mol Sci. 2021 Jan; 22(2): 695. Published online 2021 Jan 12. doi: 10.3390/ijms22020695

PMCID:: PMC7828200

Abstract Article PDF–3.3M

Select item 747836217.

Cathepsin K Is a Potent Disaggregase of α-Synuclein Fibrils

Ryan P. McGlinchey, Shannon M. Lacy, Robert L. Walker, III, Jennifer C. Lee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Sep 3.

Published in final edited form as: Biochem Biophys Res Commun. 2020 Sep 3; 529(4): 1106–1111. Published online 2020 Jul 31. doi: 10.1016/j.bbrc.2020.06.155

PMCID:: PMC7478362

Abstract Article PDF–1.1M

Select item 703121118.

Associations of Serum Cathepsin K and Polymorphisms in CTSK Gene With Bone Mineral Density and Bone Metabolism Markers in Postmenopausal Chinese Women

Li-hong Gao, Shan-shan Li, Hua Yue, Zhen-lin Zhang

Front Endocrinol (Lausanne) 2020; 11: 48. Published online 2020 Feb 13. doi: 10.3389/fendo.2020.00048

PMCID:: PMC7031211

Abstract Article PDF–345K

Select item 644378919.

Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis

Akia N. Parks, Juhi Nahata, Naomi-Eliana Edouard, Johnna S. Temenoff, Manu O. Platt

Sci Rep. 2019; 9: 5399. Published online 2019 Apr 1. doi: 10.1038/s41598-019-41782-1

PMCID:: PMC6443789

Abstract Article PDF–1.6M

Select item 634916020.

Endogenous reduction of miR‐185 accelerates cardiac function recovery in mice following myocardial infarction via targeting of cathepsin K

Chuan‐Chang Li, Xue‐Ting Qiu, Quan Sun, Ji‐Peng Zhou, Hui‐Jun Yang, Wan‐Zhou Wu, Ling‐Fang He, Can‐E Tang, Guo‐Gang Zhang, Yong‐Ping Bai

J Cell Mol Med. 2019 Feb; 23(2): 1164–1173. Published online 2018 Nov 18. doi: 10.1111/jcmm.14016

PMCID:: PMC6349160

Abstract Article PDF–3.8M

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