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Select item 112379301.

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 112099352.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111585723.

Curcumin attenuates cytochrome P450 induction in response to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin by ROS‐dependently degrading AhR and ARNT

Hyunsung Choi, Yang‐Sook Chun, Yong Jae Shin, Sang Kyu Ye, Myung‐Suk Kim, Jong‐Wan Park

Cancer Sci. 2008 Dec; 99(12): 2518–2524. Published online 2008 Nov 19. doi: 10.1111/j.1349-7006.2008.00984.x

PMCID:: PMC11158572

Abstract Article PDF–257K

Select item 111481844.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 111155555.

Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression

Wan-Chen Huang, Shu-Ting Chen, Wei-Chiao Chang, Kwang-Yu Chang, Wen-Chang Chang, Ben-Kuen Chen

Cell Mol Life Sci. 2010 Oct; 67(20): 3523–3533. Published online 2010 May 28. doi: 10.1007/s00018-010-0392-9

PMCID:: PMC11115555

Abstract Article PDF–591K

Select item 109332676.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 108698007.

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett

Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4

PMCID:: PMC10869800

Abstract Article PDF–9.3M

Select item 105658768.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 100395119.

Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology

Yanting Su, Yuanyuan Guo, Jieyu Guo, Ting Zeng, Ting Wang, Wu Liu

BMC Genomics. 2023; 24: 146. Published online 2023 Mar 24. doi: 10.1186/s12864-023-09238-z

PMCID:: PMC10039511

Abstract Article PDF–2.0M

Select item 976969810.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 967425311.

Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family

Xiangnan Sun, Linqian Jing, Fengwei Li, Meina Zhang, Xiaotong Diao, Jingjing Zhuang, Fraydoon Rastinejad, Dalei Wu

Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2208804119. Published online 2022 Nov 7. doi: 10.1073/pnas.2208804119

PMCID:: PMC9674253

Abstract Article PDF–2.7M

Select item 965552012.

Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression

Jianmin Tang, Zheng Wu, Xiaohang Wang, Yanli Hou, Yongrui Bai, Ye Tian

Cells. 2022 Nov; 11(21): 3407. Published online 2022 Oct 28. doi: 10.3390/cells11213407

PMCID:: PMC9655520

Abstract Article PDF–1.8M

Select item 934647113.

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2‐mediated degradation

Mi Chen, Shreyas Lingadahalli, Nitin Narwade, Kate Man Kei Lei, Shanshan Liu, Zuxianglan Zhao, Yimin Zheng, Qian Lu, Alexander Hin Ning Tang, Terence Chuen Wai Poon, Edwin Cheung

EMBO Rep. 2022 Aug; 23(8): e53468. Published online 2022 Jul 4. doi: 10.15252/embr.202153468

PMCID:: PMC9346471

Abstract Article PDF–5.2M

Select item 911906514.

Alternative Splicing of the Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Is Regulated by RBFOX2 in Lymphoid Malignancies

Amy M. Cooper, Curtis A. Nutter, Muge N. Kuyumcu-Martinez, Casey W. Wright

Mol Cell Biol. 2022 May; 42(5): e00503-21. Published online 2022 Apr 11. doi: 10.1128/mcb.00503-21

PMCID:: PMC9119065

Abstract Article PDF–667K

Select item 904466815.

Interaction between AhR and HIF-1 signaling pathways mediated by ARNT/HIF-1β

Mengdi Zhang, Yuxia Hu, Fan Yang, Jingwen Zhang, Jianxin Zhang, Wanjia Yu, Minjie Wang, Xiaoli Lv, Jun Li, Tuya Bai, Fuhou Chang

BMC Pharmacol Toxicol. 2022; 23: 26. Published online 2022 Apr 26. doi: 10.1186/s40360-022-00564-8

PMCID:: PMC9044668

Abstract Article PDF–1.6M

Select item 894490016.

AhR promotes phosphorylation of ARNT isoform 1 in human T cell malignancies as a switch for optimal AhR activity

Luke A. Bourner, Israel Muro, Amy M. Cooper, Barun K. Choudhury, Aaron O. Bailey, William K. Russell, Kamil Khanipov, George Golovko, Casey W. Wright

Proc Natl Acad Sci U S A. 2022 Mar 22; 119(12): e2114336119. Published online 2022 Mar 15. doi: 10.1073/pnas.2114336119

PMCID:: PMC8944900

Abstract Article PDF–2.5M

Select item 892403817.

The Contribution of Genetic Variation and Aberrant Methylation of Aryl Hydrocarbon Receptor Signaling Pathway Genes to Rheumatoid Arthritis

Tian-Ping Zhang, Rui Li, Hong-Miao Li, Nan Xiang, Zhen Tan, Guo-Sheng Wang, Xiao-Mei Li

Front Immunol. 2022; 13: 823863. Published online 2022 Mar 2. doi: 10.3389/fimmu.2022.823863

PMCID:: PMC8924038

Abstract Article PDF–645K

Select item 882889518.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 876026519.

HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia

Yongkang Yang, Haiquan Lu, Chelsey Chen, Yajing Lyu, Robert N. Cole, Gregg L. Semenza

Nat Commun. 2022; 13: 316. Published online 2022 Jan 14. doi: 10.1038/s41467-021-27944-8

PMCID:: PMC8760265

Abstract Article PDF–1.9M

Select item 863390220.

Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia‐induced FLT1 gene in placental trophoblasts

Tadashi Sasagawa, Takeshi Nagamatsu, Manami Yanagisawa, Tomoyuki Fujii, Masabumi Shibuya

Mol Hum Reprod. 2021 Dec; 27(12): gaab065. Published online 2021 Oct 19. doi: 10.1093/molehr/gaab065

PMCID:: PMC8633902

Abstract Article PDF–1.0M

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