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Select item 113159291.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104505213.

The peroxidation-derived DNA adduct, 6-oxo-M₁dG, is a strong block to replication by human DNA polymerase η

Robyn Richie-Jannetta, Pradeep Pallan, Philip J. Kingsley, Nikhil Kamdar, Martin Egli, Lawrence J. Marnett

J Biol Chem. 2023 Aug; 299(8): 105067. Published online 2023 Jul 18. doi: 10.1016/j.jbc.2023.105067

PMCID:: PMC10450521

Abstract Article PDF–2.9M

Select item 100118344.

Human DNA polymerase η promotes RNA-templated error-free repair of DNA double-strand breaks

Anirban Chakraborty, Nisha Tapryal, Azharul Islam, Altaf H. Sarker, Kodavati Manohar, Joy Mitra, Muralidhar L. Hegde, Tapas Hazra

J Biol Chem. 2023 Mar; 299(3): 102991. Published online 2023 Feb 8. doi: 10.1016/j.jbc.2023.102991

PMCID:: PMC10011834

Abstract Article PDF–3.7M

Select item 99764655.

Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase η and reduces DNA synthesis fidelity

Caleb Chang, Christie Lee Luo, Sarah Eleraky, Aaron Lin, Grace Zhou, Yang Gao

J Biol Chem. 2023 Mar; 299(3): 102938. Published online 2023 Jan 24. doi: 10.1016/j.jbc.2023.102938

PMCID:: PMC9976465

Abstract Article PDF–3.0M

Select item 98841446.

Incorporation of 5’,8-cyclo-2’deoxyadenosines by DNA repair polymerases via base excision repair

Pawlos S. Tsegay, Daniela Hernandez, Christopher Brache, Chryssostomos Chatgilialoglu, Marios G. Krokidis, Prem Chapagain, Yuan Liu

DNA Repair (Amst) Author manuscript; available in PMC 2023 Jan 28.

Published in final edited form as: DNA Repair (Amst). 2022 Jan; 109: 103258. Published online 2021 Nov 24. doi: 10.1016/j.dnarep.2021.103258

PMCID:: PMC9884144

Abstract Article PDF–2.5M

Select item 97080867.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 96428148.

DNA Polymerases Eta and Kappa Exchange with the Polymerase Delta Holoenzyme to Complete Common Fragile Site Synthesis

Ryan P. Barnes, Suzanne E. Hile, Marietta Y. Lee, Kristin A. Eckert

DNA Repair (Amst) Author manuscript; available in PMC 2022 Nov 8.

Published in final edited form as: DNA Repair (Amst). 2017 Sep; 57: 1–11. Published online 2017 Jun 3. doi: 10.1016/j.dnarep.2017.05.006

PMCID:: PMC9642814

Abstract Article PDF–1.6M

Select item 95403459.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 895585910.

Identification of Frameshift Variants in POLH Gene Causing Xeroderma Pigmentosum in Two Consanguineous Pakistani Families

Ghazala Y. Zamani, Ranjha Khan, Noreen Karim, Zubair M. Ahmed, Muhammad Naeem

Genes (Basel) 2022 Mar; 13(3): 543. Published online 2022 Mar 19. doi: 10.3390/genes13030543

PMCID:: PMC8955859

Abstract Article PDF–1.5M

Select item 882889511.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 876331712.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 874506413.

Manganese Is a Strong Specific Activator of the RNA Synthetic Activity of Human Polη

Eva Balint, Ildiko Unk

Int J Mol Sci. 2022 Jan; 23(1): 230. Published online 2021 Dec 26. doi: 10.3390/ijms23010230

PMCID:: PMC8745064

Abstract Article PDF–3.1M

Select item 864078814.

Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites

Shyam Twayana, Albino Bacolla, Angelica Barreto-Galvez, Ruth B. De-Paula, William C. Drosopoulos, Settapong T. Kosiyatrakul, Eric E. Bouhassira, John A. Tainer, Advaitha Madireddy, Carl L. Schildkraut

Proc Natl Acad Sci U S A. 2021 Nov 30; 118(48): e2106477118. Published online 2021 Nov 23. doi: 10.1073/pnas.2106477118

PMCID:: PMC8640788

Abstract Article PDF–2.6M

Select item 856095315.

Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells

Tonghui Bi, Xiaohong Niu, Chunping Qin, Wei Xiao

Sci Rep. 2021; 11: 21364. Published online 2021 Nov 1. doi: 10.1038/s41598-021-00878-3

PMCID:: PMC8560953

Abstract Article PDF–7.9M

Select item 830719416.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808827418.

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch

Agnieszka T. Kawashima, Cassandra Wong, Gema Lordén, Charles C. King, Pablo Lara-Gonzalez, Arshad Desai, Anne-Claude Gingras, Alexandra C. Newton

Mol Cell Biol. 2021 Mar; 41(3): e00333-20. Prepublished online 2021 Jan 4. Published online 2021 Feb 23. doi: 10.1128/MCB.00333-20

PMCID:: PMC8088274

Abstract Article PDF–3.1M

Select item 805077519.

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner

Lauriane Vélot, Frédéric Lessard, Félix-Antoine Bérubé-Simard, Christophe Tav, Bertrand Neveu, Valentine Teyssier, Imène Boudaoud, Ugo Dionne, Noémie Lavoie, Steve Bilodeau, Frédéric Pouliot, Nicolas Bisson

Mol Cell Proteomics. 2021; 20: 100064. Published online 2021 Feb 26. doi: 10.1016/j.mcpro.2021.100064

PMCID:: PMC8050775

Abstract Article PDF–3.6M

Select item 766962820.

Translesion synthesis of 6-nitrochrysene-derived 2ʹ-deoxyadenosine adduct in human cells

Brent V. Powell, Jan Henric T. Bacurio, Ashis K. Basu

DNA Repair (Amst) Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2020 Nov; 95: 102935. Published online 2020 Jul 18. doi: 10.1016/j.dnarep.2020.102935

PMCID:: PMC7669628

Abstract Article PDF–925K

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