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Items: 1 to 20 of 22

1.
PTB domain and leucine zipper motif 1 (APPL1) inhibits myocardial ischemia/hypoxia-reperfusion injury via inactivation of apoptotic protease activating factor-1 (APAF-1)/Caspase9 signaling pathway
Lina Bai, Junhua Yang, Hong Zhang, Wei Liao, Yunguang Cen
Bioengineered. 2021; 12(1): 4385–4396. Published online 2021 Jul 24. doi: 10.1080/21655979.2021.1954841
PMCID:
PMC8806591
AbstractArticlePDF–2.4M
2.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
3.
APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain
Jie Song, Yabing Mu, Chunyan Li, Anders Bergh, Marta Miaczynska, Carl-Henrik Heldin, Marene Landström
Oncotarget. 2016 Jan 5; 7(1): 279–292. Published online 2015 Nov 18. doi: 10.18632/oncotarget.6346
PMCID:
PMC4807998
AbstractArticlePDF–1.3M
4.
Appl1 and Appl2 are Expendable for Mouse Development but are Essential for HGF-induced Akt Activation and Migration in Mouse Embryonic Fibroblasts
Yinfei Tan, Xiaoban Xin, Francis J. Coffey, David L. Wiest, Lily Q. Dong, Joseph R. Testa
J Cell Physiol. Author manuscript; available in PMC 2016 Nov 1.
Published in final edited form as: J Cell Physiol. 2016 May; 231(5): 1142–1150. Published online 2015 Oct 21. doi: 10.1002/jcp.25211
PMCID:
PMC4728037
AbstractArticlePDF–1.6M
5.
Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus
Sabrina Prudente, Prapaporn Jungtrakoon, Antonella Marucci, Ornella Ludovico, Patinut Buranasupkajorn, Tommaso Mazza, Timothy Hastings, Teresa Milano, Eleonora Morini, Luana Mercuri, Diego Bailetti, Christine Mendonca, Federica Alberico, Giorgio Basile, Marta Romani, Elide Miccinilli, Antonio Pizzuti, Massimo Carella, Fabrizio Barbetti, Stefano Pascarella, Piero Marchetti, Vincenzo Trischitta, Rosa Di Paola, Alessandro Doria
Am J Hum Genet. 2015 Jul 2; 97(1): 177–185. doi: 10.1016/j.ajhg.2015.05.011
PMCID:
PMC4571002
AbstractArticlePDF–983K
6.
Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages
Jeremy C. Yeo, Adam A. Wall, Lin Luo, Jennifer L. Stow
Mol Biol Cell. 2015 Mar 1; 26(5): 952–965. doi: 10.1091/mbc.E14-10-1457
PMCID:
PMC4342030
AbstractArticlePDF–7.3M
7.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
8.
Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway
Liufeng Mao, Wanhua Lin, Tao Nie, Xiaoyan Hui, Xuefei Gao, Kuai Li, Mengxiao Ding, Xiaofeng Tang, Peng Li, Yu Wang, Aimin Xu, Pentao Liu, Donghai Wu
Cell Biosci. 2014; 4: 60. Published online 2014 Oct 2. doi: 10.1186/2045-3701-4-60
PMCID:
PMC4201708
AbstractArticlePDF–2.5M
9.
AdipoR1/APPL1 Potentiates the Protective Effects of Globular Adiponectin on Angiotensin II-Induced Cardiac Hypertrophy and Fibrosis in Neonatal Rat Atrial Myocytes and Fibroblasts
Tengwei Cao, Zhen Gao, Lingyun Gu, Minglong Chen, Bing Yang, Kejiang Cao, He Huang, Mingfang Li
PLoS One. 2014; 9(8): e103793. Published online 2014 Aug 6. doi: 10.1371/journal.pone.0103793
PMCID:
PMC4123880
AbstractArticlePDF–1.4M
10.
Membrane Targeting by APPL1 and APPL2: Dynamic Scaffolds that Oligomerize and Bind Phosphoinositides
Heidi J. Chial, Ruping Wu, Carolyn V. Ustach, Linda C. McPhail, William C. Mobley, Yong Q. Chen
Traffic. Author manuscript; available in PMC 2013 Oct 28.
Published in final edited form as: Traffic. 2008 Feb; 9(2): 215–229. Published online 2007 Dec 18. doi: 10.1111/j.1600-0854.2007.00680.x
Correction in:
volume 9 on page 623
PMCID:
PMC3810297
AbstractArticlePDF–1.7M
11.
Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats
Peter M Schmid, Markus Resch, Christian Schach, Christoph Birner, Guenter A Riegger, Andreas Luchner, Dierk H Endemann
Cardiovasc Diabetol. 2013; 12: 46. Published online 2013 Mar 18. doi: 10.1186/1475-2840-12-46
PMCID:
PMC3606629
AbstractArticlePDF–597K
12.
Biochemical Characterization of APPL Endosomes: The Role of Annexin A2 in APPL Membrane Recruitment
Anna Urbanska, Lukasz Sadowski, Yannis Kalaidzidis, Marta Miaczynska
Traffic. 2011 Sep; 12(9): 1227–1241. Published online 2011 Jul 3. doi: 10.1111/j.1600-0854.2011.01226.x
PMCID:
PMC3380557
AbstractArticlePDF–28M
13.
Retrolinkin cooperates with endophilin A1 to mediate BDNF–TrkB early endocytic trafficking and signaling from early endosomes
Xiuping Fu, Yanrui Yang, Chenchang Xu, Yang Niu, Tielin Chen, Qin Zhou, Jia-Jia Liu
Mol Biol Cell. 2011 Oct 1; 22(19): 3684–3698. doi: 10.1091/mbc.E11-04-0308
PMCID:
PMC3183022
AbstractArticlePDF–8.7M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes
Rajendra Kedlaya, Gokul Kandala, Tie Fu Liu, Nityanand Maddodi, Sulochana Devi, Vijayasaradhi Setaluri
Arch Biochem Biophys. Author manuscript; available in PMC 2011 Aug 4.
Published in final edited form as: Arch Biochem Biophys. 2011 Apr 15; 508(2): 227–233. Published online 2011 Feb 1. doi: 10.1016/j.abb.2011.01.021
PMCID:
PMC3149828
AbstractArticlePDF–1.0M
16.
The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway
M E Cleasby, Q Lau, E Polkinghorne, S A Patel, S J Leslie, N Turner, G J Cooney, A Xu, E W Kraegen
J Endocrinol. 2011 Jul; 210(1): 81–92. Prepublished online 2011 May 4. doi: 10.1530/JOE-11-0039
PMCID:
PMC3114475
AbstractArticlePDF–307K
17.
Globular Adiponectin, Acting via AdipoR1/APPL1, Protects H9c2 Cells from Hypoxia/Reoxygenation-Induced Apoptosis
Min Park, ByungSoo Youn, Xi-long Zheng, Donghai Wu, Aimin Xu, Gary Sweeney
PLoS One. 2011; 6(4): e19143. Published online 2011 Apr 28. doi: 10.1371/journal.pone.0019143
PMCID:
PMC3084258
AbstractArticlePDF–844K
18.
An APPL1/Akt Signaling Complex Regulates Dendritic Spine and Synapse Formation in Hippocampal Neurons
Devi Majumdar, Caroline A. Nebhan, Lan Hu, Bridget Anderson, Donna J. Webb
Mol Cell Neurosci. Author manuscript; available in PMC 2012 Mar 1.
Published in final edited form as: Mol Cell Neurosci. 2011 Mar; 46(3): 633–644. Published online 2011 Jan 12. doi: 10.1016/j.mcn.2011.01.003
PMCID:
PMC3046229
AbstractArticlePDF–2.8M
19.
Yin-Yang Regulation of Adiponectin Signaling by APPL Isoforms in Muscle Cells
Changhua Wang, Xiaoban Xin, Ruihua Xiang, Fresnida J. Ramos, Meilian Liu, Hak Joo Lee, Hongzhi Chen, Xuming Mao, Chintan K. Kikani, Feng Liu, Lily Q. Dong
J Biol Chem. 2009 Nov 13; 284(46): 31608–31615. Published online 2009 Aug 6. doi: 10.1074/jbc.M109.010355
PMCID:
PMC2797231
AbstractArticlePDF–2.8M
20.
Endosomal Adaptor Proteins APPL1 and APPL2 Are Novel Activators of β-Catenin/TCF-mediated Transcription
Sajid Rashid, Iwona Pilecka, Anna Torun, Marta Olchowik, Beata Bielinska, Marta Miaczynska
J Biol Chem. 2009 Jul 3; 284(27): 18115–18128. Published online 2009 May 11. doi: 10.1074/jbc.M109.007237
PMCID:
PMC2709337
AbstractArticlePDF–4.2M

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