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Select item 98202181.

TRPC3-Nox2 Protein Complex Formation Increases the Risk of SARS-CoV-2 Spike Protein-Induced Cardiomyocyte Dysfunction through ACE2 Upregulation

Yuri Kato, Kazuhiro Nishiyama, Jae Man Lee, Yuko Ibuki, Yumiko Imai, Takamasa Noda, Noriho Kamiya, Takahiro Kusakabe, Yasunari Kanda, Motohiro Nishida

Int J Mol Sci. 2023 Jan; 24(1): 102. Published online 2022 Dec 21. doi: 10.3390/ijms24010102

PMCID:: PMC9820218

Abstract Article PDF–1.5M

Select item 64866762.

Transient Receptor Potential Canonical 3 and Nuclear Factor of Activated T Cells C3 Signaling Pathway Critically Regulates Myocardial Fibrosis

Youakim Saliba, Victor Jebara, Joelle Hajal, Richard Maroun, Stéphanie Chacar, Viviane Smayra, Joel Abramowitz, Lutz Birnbaumer, Nassim Farès

Antioxid Redox Signal. 2019 Jun 1; 30(16): 1851–1879. Published online 2019 Apr 11. doi: 10.1089/ars.2018.7545

PMCID:: PMC6486676

Abstract Article PDF–3.8M

Select item 58065913.

Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits

Hidehiko Koizumi, Tibin T. John, Justine X. Chia, Mohammad F. Tariq, Ryan S. Phillips, Bryan Mosher, Yonghua Chen, Ryan Thompson, Ruli Zhang, Naohiro Koshiya, Jeffrey C. Smith

eNeuro. 2018 Jan-Feb; 5(1): ENEURO.0332-17.2018. Prepublished online 2018 Jan 31. Published online 2018 Feb 9. doi: 10.1523/ENEURO.0332-17.2018

PMCID:: PMC5806591

Abstract Article PDF–6.3M

Select item 55863014.

Enhanced Mitochondrial Transient Receptor Potential Channel, Canonical Type 3–Mediated Calcium Handling in the Vasculature From Hypertensive Rats

Bin Wang, Shiqiang Xiong, Shaoyang Lin, Weijie Xia, Qiang Li, Zhigang Zhao, Xing Wei, Zongshi Lu, Xiao Wei, Peng Gao, Daoyan Liu, Zhiming Zhu

J Am Heart Assoc. 2017 Jul; 6(7): e005812. Published online 2017 Jul 15. doi: 10.1161/JAHA.117.005812

PMCID:: PMC5586301

Abstract Article PDF–3.0M

Select item 51051345.

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

Naoyuki Kitajima, Takuro Numaga-Tomita, Masahiko Watanabe, Takuya Kuroda, Akiyuki Nishimura, Kei Miyano, Satoshi Yasuda, Koichiro Kuwahara, Yoji Sato, Tomomi Ide, Lutz Birnbaumer, Hideki Sumimoto, Yasuo Mori, Motohiro Nishida

Sci Rep. 2016; 6: 37001. Published online 2016 Nov 11. doi: 10.1038/srep37001

PMCID:: PMC5105134

Abstract Article PDF–2.6M

Select item 45201586.

Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca²⁺ Channel in Renal Fibrosis

Youakim Saliba, Ralph Karam, Viviane Smayra, Georges Aftimos, Joel Abramowitz, Lutz Birnbaumer, Nassim Farès

J Am Soc Nephrol. 2015 Aug; 26(8): 1855–1876. Published online 2014 Dec 5. doi: 10.1681/ASN.2014010065

PMCID:: PMC4520158

Abstract Article

Select item 43972137.

Divergence in Endothelin-1- and Bradykinin-Activated Store-Operated Calcium Entry in Afferent Sensory Neurons

Kalina Szteyn, Ruben Gomez, Kelly A Berg, Nathaniel A Jeske

ASN Neuro. 2015 Mar-Apr; 7(2): 1759091415578714. Published online 2015 Mar 27. doi: 10.1177/1759091415578714

PMCID:: PMC4397213

Abstract Article PDF–929K

Select item 41402908.

Brain-derived Neurotrophic Factor (BDNF) Induces Sustained Intracellular Ca²⁺ Elevation through the Up-regulation of Surface Transient Receptor Potential 3 (TRPC3) Channels in Rodent Microglia

Yoshito Mizoguchi, Takahiro A. Kato, Yoshihiro Seki, Masahiro Ohgidani, Noriaki Sagata, Hideki Horikawa, Yusuke Yamauchi, Mina Sato-Kasai, Kohei Hayakawa, Ryuji Inoue, Shigenobu Kanba, Akira Monji

J Biol Chem. 2014 Jun 27; 289(26): 18549–18555. Published online 2014 May 8. doi: 10.1074/jbc.M114.555334

PMCID:: PMC4140290

Abstract Article PDF–686K

Select item 41183159.

Contribution of TRPC3 to store-operated calcium entry and inflammatory transductions in primary nociceptors

Hazim Alkhani, Ariel R Ase, Rebecca Grant, Dajan O’Donnell, Klaus Groschner, Philippe Séguéla

Mol Pain. 2014; 10: 43. Published online 2014 Jun 26. doi: 10.1186/1744-8069-10-43

PMCID:: PMC4118315

Abstract Article PDF–706K

Select item 382297310.

Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling

Wenfeng Chu, Lin Wan, Dan Zhao, Xuefeng Qu, Fulai Cai, Rong Huo, Ning Wang, Jiuxin Zhu, Chun Zhang, Fangfang Zheng, Ruijun Cai, Deli Dong, Yanjie Lu, Baofeng Yang

J Cell Mol Med. 2012 Sep; 16(9): 2022–2034. Published online 2012 Aug 23. doi: 10.1111/j.1582-4934.2011.01497.x

PMCID:: PMC3822973

Abstract Article PDF–1.2M

Select item 370401011.

Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake

Shengjie Feng, Hongyu Li, Yilin Tai, Junbo Huang, Yujuan Su, Joel Abramowitz, Michael X. Zhu, Lutz Birnbaumer, Yizheng Wang

Proc Natl Acad Sci U S A. 2013 Jul 2; 110(27): 11011–11016. Published online 2013 Jun 17. doi: 10.1073/pnas.1309531110

PMCID:: PMC3704010

Abstract Article PDF–1.3M

Select item 363226412.

An Elevation in Physical Coupling of Type 1 IP₃ Receptors to TRPC3 Channels Constricts Mesenteric Arteries in Genetic Hypertension

Adebowale Adebiyi, Candice M. Thomas-Gatewood, M. Dennis Leo, Michael W. Kidd, Zachary P. Neeb, Jonathan H. Jaggar

Hypertension. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Hypertension. 2012 Nov; 60(5): 1213–1219. Published online 2012 Oct 8. doi: 10.1161/HYPERTENSIONAHA.112.198820

PMCID:: PMC3632264

Abstract Article PDF–2.5M

Select item 343722913.

Transient Receptor Potential Canonical 3 (TRPC3) Is Required for IgG Immune Complex-Induced Excitation of the Rat Dorsal Root Ganglion Neurons

Lintao Qu, Yumei Li, Xinghua Pan, Pu Zhang, Robert H. LaMotte, Chao Ma

J Neurosci. 2012 Jul 11; 32(28): 9554–9562. doi: 10.1523/JNEUROSCI.6355-11.2012

PMCID:: PMC3437229

Abstract Article PDF–1.1M

Select item 342207914.

Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity

Sevvandi Senadheera, Youngsoo Kim, T. Hilton Grayson, Sianne Toemoe, Mikhail Y. Kochukov, Joel Abramowitz, Gary D. Housley, Rebecca L. Bertrand, Preet S. Chadha, Paul P. Bertrand, Timothy V. Murphy, Marianne Tare, Lutz Birnbaumer, Sean P. Marrelli, Shaun L. Sandow

Cardiovasc Res. 2012 Sep 1; 95(4): 439–447. Published online 2012 Jun 21. doi: 10.1093/cvr/cvs208