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Select item 98519731.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 94486392.

Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression

Avishai Shemesh, Yapeng Su, Daniel R. Calabrese, Daniel Chen, Janice Arakawa-Hoyt, Kole T. Roybal, James R. Heath, John R. Greenland, Lewis L. Lanier

J Exp Med. 2022 Nov 7; 219(11): e20220551. Published online 2022 Sep 6. doi: 10.1084/jem.20220551

PMCID:: PMC9448639

Abstract Article PDF–7.0M

Select item 87909133.

The role of SPI1-TYROBP-FCER1G network in oncogenesis and prognosis of osteosarcoma, and its association with immune infiltration

Jiahua Li, Hui Shi, Zhanyuan Yuan, Zhiheng Wu, Haohao Li, Yuelong Liu, Ming Lu, Ming Lu

BMC Cancer. 2022; 22: 108. Published online 2022 Jan 25. doi: 10.1186/s12885-022-09216-w

PMCID:: PMC8790913

Abstract Article PDF–8.7M

Select item 83429874.

TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity

Xueer Wang, Honghai Zhang, Zhugui Shao, Wanxin Zhuang, Chao Sui, Feng Liu, Xiaorong Chen, Jinxiu Hou, Lingli Kong, Hansen Liu, Yi Zheng, Bingyu Liu, Tian Chen, Lei Zhang, Xinming Jia, Chengjiang Gao

Signal Transduct Target Ther. 2021; 6: 298. Published online 2021 Aug 6. doi: 10.1038/s41392-021-00711-3

PMCID:: PMC8342987

Abstract Article PDF–6.2M

Select item 75267225.

Phosphorylated tau interactome in the human Alzheimer’s disease brain

Eleanor Drummond, Geoffrey Pires, Claire MacMurray, Manor Askenazi, Shruti Nayak, Marie Bourdon, Jiri Safar, Beatrix Ueberheide, Thomas Wisniewski

Brain. 2020 Sep; 143(9): 2803–2817. Published online 2020 Aug 19. doi: 10.1093/brain/awaa223

PMCID:: PMC7526722

Abstract Article PDF–1.1M

Select item 73220676.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69084688.

Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C

Kyung Hwan Kim, Hee Tae Yu, Ilwoong Hwang, Sungha Park, Su-Hyung Park, Sungjin Kim, Eui-Cheol Shin

Front Immunol. 2019; 10: 2865. Published online 2019 Dec 6. doi: 10.3389/fimmu.2019.02865

PMCID:: PMC6908468

Abstract Article PDF–1.9M

Select item 64855079.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand

Blood. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269

PMCID:: PMC6485507

Abstract Article PDF–4.4M

Select item 571552010.

Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma

Liang Chen, Lushun Yuan, Yongzhi Wang, Gang Wang, Yuan Zhu, Rui Cao, Guofeng Qian, Conghua Xie, Xuefeng Liu, Yu Xiao, Xinghuan Wang

Int J Biol Sci. 2017; 13(11): 1361–1372. Published online 2017 Nov 1. doi: 10.7150/ijbs.21657

PMCID:: PMC5715520

Abstract Article PDF–2.6M

Select item 551476011.

Transmembrane features governing Fc receptor CD16A assembly with CD16A signaling adaptor molecules

Alfonso Blázquez-Moreno, Soohyung Park, Wonpil Im, Melissa J. Call, Matthew E. Call, Hugh T. Reyburn

Proc Natl Acad Sci U S A. 2017 Jul 11; 114(28): E5645–E5654. Published online 2017 Jun 26. doi: 10.1073/pnas.1706483114

PMCID:: PMC5514760

Abstract Article PDF–1.8M

Select item 523590712.

Regulation of FcRγ function by site-specific serine phosphorylation

Spandan Shah, Andrew W. Gibson, Chuanyi Ji, Eric Darrington, James Mobley, Kyoko Kojima, Jeffrey C. Edberg, Robert P. Kimberly

J Leukoc Biol. 2017 Feb; 101(2): 421–428. Published online 2016 Sep 14. doi: 10.1189/jlb.2AB0516-228R

PMCID:: PMC5235907

Abstract Article

Select item 511000013.

FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes

Ellen B. Duffy, Sivakumar Periasamy, Danielle Hunt, James R. Drake, Jonathan A. Harton

J Leukoc Biol. 2016 Dec; 100(6): 1335–1347. Published online 2016 Jun 30. doi: 10.1189/jlb.2A1215-555RR

PMCID:: PMC5110000

Abstract Article

Select item 459599614.

TARM1 is a novel LRC-encoded ITAM receptor that co-stimulates pro-inflammatory cytokine secretion by macrophages and neutrophils

Valeria Radjabova, Piero Mastroeni, Karsten Skjødt, Paola Zaccone, Bernard de Bono, Jane C Goodall, Edwin R Chilvers, Jatinder K Juss, Des C Jones, John Trowsdale, Alexander David Barrow

J Immunol. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: J Immunol. 2015 Oct 1; 195(7): 3149–3159. Published online 2015 Aug 26. doi: 10.4049/jimmunol.1401847

PMCID:: PMC4595996

Abstract Article PDF–3.1M

Select item 433746015.

Characteristics of TCRζ, ZAP-70, and FcɛRIγ Gene Expression in Patients with T- and NK/T-Cell Lymphoma

Ziwei Liao, Lingling Zhou, Chunyan Wang, Zhifeng He, Xu Wang, Xiaodan Luo, Shaohua Chen, Lijian Yang, Huo Tan, Yangqiu Li

DNA Cell Biol. 2015 Mar 1; 34(3): 201–207. doi: 10.1089/dna.2014.2693

PMCID:: PMC4337460

Abstract Article PDF–815K

Select item 400459816.

Systematic identification of pathological lamin A interactors

Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli

Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733

PMCID:: PMC4004598

Abstract Article PDF–3.5M

Select item 370996617.

HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

Carlos A. Barrero, Prasun K. Datta, Satarupa Sen, Satish Deshmane, Shohreh Amini, Kamel Khalili, Salim Merali

PLoS One. 2013; 8(7): e68376. Published online 2013 Jul 12. doi: 10.1371/journal.pone.0068376

PMCID:: PMC3709966

Abstract Article PDF–1.3M

Select item 366535218.

CD2AP/SHIP1 Complex Positively Regulates Plasmacytoid Dendritic Cell Receptor Signaling by Inhibiting the E3 Ubiquitin Ligase Cbl

Musheng Bao, Shino Hanabuchi, Valeria Facchinetti, Qiumei Du, Laura Bover, Joel Plumas, Laurence Chaperot, Wei Cao, Jun Qin, Shao-Cong Sun, Yong-Jun Liu

J Immunol. Author manuscript; available in PMC 2013 Jul 15.

Published in final edited form as: J Immunol. 2012 Jul 15; 189(2): 786–792. Published online 2012 Jun 15. doi: 10.4049/jimmunol.1200887

PMCID:: PMC3665352

Abstract Article PDF–3.9M

Select item 354463019.

Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia

Xianfeng Zha, Xiaojuan Yan, Qi Shen, Yuping Zhang, Xiuli Wu, Shaohua Chen, Bo Li, Lijian Yang, Suxia Geng, Jianyu Weng, Xin Du, Yangqiu Li

J Hematol Oncol. 2012; 5: 74. Published online 2012 Dec 10. doi: 10.1186/1756-8722-5-74

PMCID:: PMC3544630

Abstract Article PDF–1.9M

Select item 335923920.

Altered expression of the TCR signaling related genes CD3 and FcεRIγ in patients with aplastic anemia

Bo Li, Sichu Liu, Yuzhe Niu, Su Fang, Xiuli Wu, Zhi Yu, Shaohua Chen, Lijian Yang, Yangqiu Li

J Hematol Oncol. 2012; 5: 6. Published online 2012 Mar 8. doi: 10.1186/1756-8722-5-6

PMCID:: PMC3359239

Abstract Article PDF–374K

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